Eating Disorders Flashcards

(51 cards)

1
Q

what is the DSM-5 criteria for anorexia nervosa?

A
  • intense fear of gaining weight or becoming fat
  • significantly low body weight (less than what is ideally expected) in related to age, sex, development and physical health
  • disturbances in the way ones body weight or shape is experienced and denial of the seriousness of the current low body weight
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2
Q

what are the two subtypes of anorexia and how are they different?

A

restricting type: during the last 3 months, the individual has not engaged in recurrent episodes of binge eating or purging behaviour
- weight is accomplished primarily through dieting, fasting, and/or excessive exercise

binge-eating/purging type: during the last 3 months, the individual has engaged in recurrent episodes of binge eating or purging behaviour

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3
Q

how is the severity of anorexia classified?

A

based on BMI

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4
Q

what is the DSM-5 criteria for bulimia nervosa?

A
  • recurrent episodes of binge eating
  • recurrent compensatory behaviour to prevent weight gain
  • binge eating and compensation 1x/week x 3 months
  • self-evaluation is disproportionately influenced by body shape and weight
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5
Q

what are the remission specifications of bulimia?

A

in partial remission: after full criteria for BN were previously met, some but not all, of the criteria have been met for a sustained period of time

in full remission: after full criteria for BN were previously met, none of the criteria have been met for a sustained period of time

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6
Q

how is the severity of bulimia classified?

A

based on the frequency of inappropriate compensatory behaviours per week

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7
Q

T or F
diagnosis for bulimia nervosa includes specific BMI?

A

false
patients with BN are commonly normal to slightly overweight

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8
Q

what BMI is considered underweight?

A

<18.5

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9
Q

what is the diagnostic criteria for binge eating disorder?

A
  • recurrent episodes of binge eating without compensatory behaviour to prevent weight gain
  • eating, in a discrete period of time, an amount of food much larger than most people would eat during the same period of time
  • lack of control over eating during the episode
  • > 3 of the following: eating rapidly; eating until uncomfortably full; eating large amounts when not hungry; eating alone from embarrassment; feeling disgusted, depressed or guilty after eating
  • binge eating 1x/weekly for 3 months
  • causes marked distress
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10
Q

what is the etiology of eating disorders?

A

genetic predisposition

physiologic state: imbalance of NTs and neuropeptides

environmental - complex bio-psychosocial

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11
Q

what is the major appetite and eating control center of the brain?

A

hypothalamus

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12
Q

what is the most common trigger for binge eating?

A

stress

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13
Q

what does suppression of the HPG axis cause?

A

decrease in estradiol, progesterone, and LH production = amenorrhea and decreased libido

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14
Q

what is the average episode duration of AN and BN?

A

AN: 8 months
BN: 2.9 months

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15
Q

what is the mean duration of illness of AN and BN?

A

AN: 9-15 years
BN: 7.7-11.7 years

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16
Q

what is the death rate of AN?

A

10%

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17
Q

which tends to be more fluctuating, AN or BN?

A

BN

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18
Q

what are some common psych co-morbidities of anorexia?

A

anxiety: OCD, social phobia
mood disorders: MDD, dysthymia, bipolar
personality disorders - cluster C: avoidant, obsessive compulsive
substance use disorder

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19
Q

what are some common psych co-morbidities of bulimia?

A

cluster B and C personality disorders: borderline, avoidant, impulsive, narcissistic
substance use
anxiety: OCD, panic, social
mood disorders: MDD, dysthymia, bipolar
impulse control disorder: compulsive buying, kleptomania, self-mutilation

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20
Q

what are the consequences of amenorrhea?

A

increase risk of
- osteoporosis/osteopenia
- decreased growth velocity
- lack of sexual desire/sexual dysfunction
- unexpected pregnancies

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21
Q

what percentage of women have a relapse in their eating disorder during pregnancy?

22
Q

what are the risks to the baby if a women suffers with anorexia during pregnancy?

A

17% newborns failure to thrive
increased risk of child obesity

23
Q

when will periods return after amenorrhea caused by an eating disorder?

A

within 6 months of achieving body weight of about 90% of the average for age and height
- related to serum estrogen, but amount of body fat

24
Q

what the the CV complications associated with anorexia?

A
  • prolonged QT
  • cardiac atrophy
  • myocardial mass
  • sinus bradycardia
  • cardiac arrhythmias
  • decrease HR variability
  • hypotension
25
what is myocardial mass and why does it occur in anorexia?
prolonged starvation leads to wasted cardiac muscle myofibrillar atrophy and destruction secondary to malnutrition +/- due to decreased preload
26
T or F most CV abnormalities normalise with weight restoration
true
27
what cardiac complication is seen with chronic ipecac ingestion?
irreversible myocarditis
28
what is the most common arrhythmia seen in anorexia?
bradycardia
29
what is the treatment of gastroparesis in anorexia?
domperidone avoid metoclopramide as can cause EPS
30
what is the treatment of constipation in anorexia?
bowel retraining: PegLyte, Peg, milk of magnesia bowel taper: sennosides or cascara prn
31
how do eating disorders contribute to osteoporosis?
- decrease nutrition = decrease peak bone mass - decrease body weight = amenorrhea = decrease estrogen levels - decrease serum androgen levels - decrease levels of IGF-1 - increase cortisol levels
32
what percentage of people with anorexia have osteoporosis/osteopenia?
40-66% osteoporosis 92% osteopenia
33
is estrogen replacement useful for preventing osteoporosis in eating disorders?
no
34
what is the recommended daily intake of calcium and vitamin D in eating disorders?
1200-1500 mg calcium 1000 IU vitamin D
35
are bisphosphonates useful in preventing osteoporosis in anorexia?
maybe?
36
what is the best way to prevent osteoporosis in eating disorders?
weight recovery
37
what are some skin complications seen in eating disorders?
- dry, scaling skin - calluses on back of hand (from purging) - hair loss - lanugo hair (fine hair growing on the skin)
38
what is refeeding syndrome?
occurs when malnourished patients are fed high CHO loads
39
what are the complications of refeeding syndrome?
may precipitate cardiac changes and heart failure
40
what are symptoms of refeeding syndrome?
gastric bloating nausea edema
41
when is cardiac decompensation at the highest risk in refeeding syndrome?
in initial phases of reintroduction of nutrition
42
is pharmacotherapy effective in treating anorexia?
no
43
which mineral is recommended for anorexic patients and why?
zinc individuals with zinc deficiency exhibit symptoms similar to anorexia
44
which antipsychotic is recommended in anorexia?
olanzapine shown modest weight increases but should be used in combination with behavioural interventions
45
which antidepressant is CI in eating disorders?
bupropion can precipitate seizures TCAs not recommended due to OD risk and potential for fatal arrhythmias
46
are antidepressants useful in eating disorders?
yes but only after weight restoration
47
what are some complications associated with bulimia?
symptoms of purging - parotid gland enlargement - callus on dorsum of hand - dental caries - esophageal rupture - gastric rupture consequences of abused substances - electrolyte imbalance - serious cardiac/skeletal myopathies and death from ipecac - irreversible submucosal nerve fiber damage from phenothalein amenorrhea orthostatic hypotension, bradycardia, ECG changes osteoporosis/osteopenia guilt and depression after binge
48
what is the most effective psychotherapy in eating disorders?
CBT
49
what are the drug of choice for bulimia?
SSRIs topiramate also has shown short term efficacy
50
what is the only FDA approved medication for bulimia?
fluoxetine
51