Ed's Cardiac Output Lecture / Final Exam Prep Flashcards

1
Q

Cardiac Output

Formula ?

A
C.O      =  HR           X   SV
ml/min = beats/min X ml/beat
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2
Q

Cardiac Output (resting range)

A

4 - 8 L/m

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3
Q

6 Factors affecting Cardiac Output

MOBGAP

A
  • Metabolic rate
  • Oxygen demand
  • Body size / type
  • Gender
  • Age
  • Posture
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4
Q

The most potent determinate of cardiac output is

A

metabolic oxygen demand

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5
Q

5 Things that increase metabolism:

A
  • exercise
  • sepsis
  • strong emotion
  • trauma/surgery
  • temperature
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6
Q

C.O. of a female Vs. C.O. of a male?

A

female = 10% lower than a male of the same body size

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7
Q

In general, females have ____ skeletal muscle mass than males.

A

Smaller

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8
Q

How do we adjust for individual differences??

A
  • Calculate cardiac index!
  • Adjusts C.O. to a
    defined measurement
    Of body tissue
    (BSA)
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9
Q

Cardiac Index formula ?

A

C.O. / BSA

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10
Q

Normal adult C.I. range?

A

2.5 - 4.2 L/min/m2

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11
Q

How do we calculate BSA??

A

(w^.425)(H^.725)(.007184)

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12
Q

Advantages of CI ?

A

Normalizes cardiac output relative to body surface area

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13
Q

Disadvantages of CI ?

A

The relationship of metabolism to surface area can be very different from patient to patient

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14
Q

When is CI at its highest?

A

Childhood

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15
Q

Neonates may have

A

X3 the CI as an adult

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16
Q

when a person stands up, what happen?

A

C.O. decreases

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17
Q

S.V. formula =

A

C.O. / HR X1000

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18
Q

DO2 (delivery) formula=

A

CaO2 X C.O. X 10

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19
Q

PVR formula =

A

80 X (MPAP-PAWP) /C.O.

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20
Q

SVR formula =

A

80 X (MAP - RAP) / C.O.

21
Q

Stroke volume is a function of:

A

A. Preload (EDP)
B. Afterload (Pa)
C. Contractility

22
Q

Normal S.V. =

A

60 - 100 ml/beat

23
Q

E.F. Formula =

A

S.V. X 100 / EDV

24
Q

Normal E.F. =

A

65%

25
Q

Frank-Starling Law

describes what?

A

relationship between SV and cardiac performance

26
Q

Preload definition = LVEDP
y = Press
X = Volume

A
the amount of -myocardial fiber 
  stretch &/or
- amount of volume in 
  the ventricle
at the end of diastole
27
Q

Afterload definition =

A

resistance, impedance, pressure the ventricles must overcome

To eject its blood volume

28
Q

Clinically the most sensitive measure of afterload is ?

A

SVR/PVR

29
Q

SVR formula =

A

(MAP-RAP) X 80
_________________
C.O.

30
Q

PVR formula =

A

(MPAP - PAWP) X 80
_________________
C.O.

31
Q

What has an inverse relationship to afterload ?

A

Afterload

32
Q

Inotrophism definition ?

A

inherent property of shortening of the myocardial

muscle fibers, apart from preload

33
Q

What pathologies invalidate that the RV C.O. and LV C.O. are equal ?

A
  • Intra-cardiac shunts

- Reguritant lesions

34
Q

3 Invasive techniques to measure C.O. ?

A

Fick Method
Dye dilution
Thermal dilution

35
Q

2 Non Invasive techniques to measure C.O. ?

A

Doppler

Bioimpedance

36
Q

3 requirements for the Fick Principle?

A
  • Arterial sample
  • Mixed venous sample
  • Spirometer
37
Q

Fick Principle measures what ?

A
  1. total O2 uptake per minute 2. amount into each 100 cc blood
38
Q

The Fick method for cardiac output determination equation ?

A

C.O. (Q) = VO2
____________
CaO2 - CvO2 X 10

39
Q

“Gold standard” for measuring CO is ?

A

Thermodilution

40
Q

What are the two methods of thermodilution that are available:

A

1) bolus thermodilution

2) continuous cardiac output (CCO)

41
Q

Catheter in the pulmonary artery monitors change in temperature of passing blood after a bolus of room temperature saline is deposited into the right atrium.

A

Thermodilution Method

42
Q

In thermodilution process, the injectate port should be in ?

A
SVC 
or
IVC
or 
RA
43
Q

In thermodilution process, the thermistor to monitor the blood’s temperature is located near the catheter’s distal tip, which should lie in ?

A

PA

44
Q

to calculate the area beneath the curve. This area is

inversely proportional to what ?

A

C.O.

45
Q

Small area under the curve =

A

higher C.O.

46
Q

Large area under the curve =

A

lower C.O.

47
Q

In bolus thermodilution, the CO curve is

displayed on the monitor and validates

A

Correct Injection technique

48
Q

The accuracy of the thermodilution method depends on several assumptions:

A

1) Blood and injectant have mixed adequately.
2) Blood flow is forward. 3) Baseline temperature in the PA is steady.
4) Appropriate technique is used.