Ehlors Danlos/Hypermobility- Common Co Travelers Flashcards
(13 cards)
EDS/Hypermoblity is often associated with what 4 other conditions?
Dysautonomia, mast cell activation syndrome, autoimmune disease, and gastrointestinal dysmotility
What is the main neurotransmitter of the PNS and SNS?
PNS- acetylcholine
SNS- Epinepherine
Why is cervical position important to understand in regards to vagus nerve function?
The vagus nerve is located in brain stem between the cranium and 1st cervical vertebrae. If cervical position is compromised, such as in chiari malformation or intracranial hypertension, then function of the vagus is compromised as is PNS regulation.
Why are craniocervical instability and dysautonomia related?
The vagus nerve, along with cranial nerve 9 and 11 exit through the posterior cranium. If the foremen magnum translates forward because of craniocervical instability, then nerve transmission will be affected
Which part of the nervous system governs digestive function, what are 2 of the 30 neurotransmitters present in this system and what percentage of these neurotransmitters are located here?
Enteric nervous system
80% of serotonin, 50% of dopamine
What system is most prominently affected by dysautonomia, according to this author?
The CV system
When autonomic health is optimal, how many L of blood are pumped per minute?
5L
How is the vascular tank affected by dysautonomia?
Loss of vascular constriction and poor venous return, therefore leading to gravitational pooling in the lower parts of the body. Think
How can you know if someone has gone too far into parasympathetic body states?
They can’t generate enough of a sympathethic response to create venous return of blood back to the heart, which will be seen through them getting dizzy upon standing from seated
Venoptosis is common in HEDS. What is it and how can it affect the client?
EDS folks veins’ will experience distention because of orthostatic pressure. This makes managing venous blood return superiorly more problematic and blood pooling inferiorly.
What is the aldosterone paradox?
When dysautonomia creates pooling in the lower half of the body, the kidney’s mistake this as an excess of fluid. In response, they increase production of urine in order to remove the excess fluid and electrolytes. This can leave someone dehydrated.`
When venous return is reduced, cardiac preload stops. Whats the consequence?
Reduced stroke volume and there reduced cardiac output
In the presence of blood pooling, the neuro-cardiovascular system employs 2 mechanisms to account for reduced stroke volume. What are they and how do they work?
- Increased heart rate, however, this fails because there is never enough blood filling the ventricles
- Increase sympathetic activation to increase adrenaline and noradrenaline secretion, and therefore greater vascular constriction and pumping
