Electrical Stimulation Part 1 Flashcards
(67 cards)
Charge:
loss or gain of electrons, measured in coulombs
Polarity:
cathode (-) anode (+) Attraction/repulsion forces = electric field. Alkaline reactions under the cathode softens underlying tissues.
The medication is (+) what charge should the machine be to drive the medication into the body
(+); like polarities repel each other
Voltage:
driving force that moves electrons, a measure of potential energy
Conductor examples:
water, metal, nerves; anything that helps the electrons along their way
Insulator examples:
rubber, plastic, fat; anything that inhibits the transmission
Properties of electrically excitable cell
resting membrane potential (RMP) -70mv usually, Action Potential, Propagation of an Action Potential (movement of the action potential along the nerve)
The cell membrane is more permeable to _____ in comparison with _____________ and negatively-charged proteins (anions).
potassium (K+), sodium (Na+)
An electrical potential is generated across the cell membrane due to the higher concentrations of K+ and anions on the ____ of the cell relative to the concentration of Na+ on the ____
inside, outside
A ____ charge is produced within the cell and a positive charge develops on the outside of the cell as the ____ charged K+ diffuses from the cell
negative, positive
RMP is ____mV to ____mV for excitable cells
-60, -90
RMP is maintained by:
an active sodium potassium pump that takes in K+ and extrudes Na+
A stimulus causes the cell membrane to become more ____ to ___ ions
permeable, Na+
An action potential is generated when the influx of ____ causes a reduction of RMP which occurs slowly at first. Reduction in the RMP is called _____.
Na+, depolarization
When transmembrane potential reaches a critical threshold level (approximately ____mV), the voltage-sensitive Na+ and K+ channels ___.
-55, open widely
Permeability to Na+ increases _____, whereas the permeability to K+ increases _____.
rapidly, slowly
During depolarization, transmembrane potential might rise as high as ____mV. A positive charge is generated inside the cell and a negative charge outside is produced, as a result of the flow of ions.
+35
The ___ channels are fully open about the time the ___ are closed and ___rushes rapidly out of the cell, making the transmembrane potential progressively more negative. This process is repolarization.
K+, Na+, K+
The ____ channels remain open long enough to repolarize the membrane (_________mv <RMP). This is called hyperpolarization.
K+, 10-20
The ____ channels close and passive diffusion of the ions ____ returns the RMP to its initial level.
K+, rapidly
Opening of the Na+ and K+ channels and voltage changes that produce a AP at one segment of the membrane triggers successive depolarization in adjacent regions of the ____, _____, or ____
nerve, muscle, membrane
AP movement occurs along the ____ of the nerve or muscle cell
surface
Movement of the AP along an unmyelinated nerve is generated via sequential depolarization (____) along neighboring sites in the nerve membrane.
eddy currents
Speed of conduction in ____ diameter fibers is ____ because of the greater internal resistance in the small fibers.
small, slow