Electrographic Correlates

Question 1

This drug initially produces diffuse beta, followed by generalized slowing, followed then by burst suppression and finally, (if titrated further) ECI: A) Diazepam B) Lorazepam C) Phenobarbital, D) Propofol E) All the above

Answer 1

All the above

Question 2

Which of the following is considered a “signature” of a mesial temporal lobe seizure? A) diffuse high voltage slow followed by paroxysmal fast activity+electrodecrement, B) Generalized 3.5-6Hzpolyspike and wave, C) evolving unilateral 5-9Hz focal theta-alpha discharges,D)unilateral 2-5Hz delta

Answer 2

C unilateral evolving 5-9Hz focal theta-alpha discharges

Question 3

What are 2 features of periodic discharges that indicate that they are associated with a higher chance of acute seizures?

Answer 3

Frequency >1.5Hz, a plus modifier (+F, +R, +FR)

Question 4

Distinctive, high amplitude, diphasic spike orsharp wave in midtemporal (T3, T4) and central (C3, C4) regions with prominentslow wave with marked sleep activation is associated with which epilepsysyndrome?

Answer 4

Childhood epilepsy with centrotemporal spikes.

Question 5

An EEG shows 3.1Hz spike-wave discharges lasting12 seconds. There are NO associated clinical changes. This would be classified as which of the following? A) BIRDs, B) electrographic seizure, C)Electrographic status epilepticus, D) Frequent epileptiform discharges

Answer 5

B electrographic seizure

Question 6

Describethe sequence of changes observed on the EEG with progressive ischemia

Answer 6

Loss of beta frequencies, Slowing 5-7Hz theta, Slowing 1-4Hz, Suppression

Question 7

Describe the ictal and interictal EEG findings of infantile spasms

Answer 7

I: Gen slow wave followed by diffuse attenuation or electrodecrement and low amplitude fast. IN: hypsarrhythmia

Question 8

Describe differences in appearance of activity recorded by intracranial electrodes compared to scalp electrodes

Answer 8

Background activity and normal transients appear more sharply contoured. EMG artifact does not obscure brain activity, seizures are detected earlier more often than scalp, interictal spikes have greater prevalence and are more present in more locations, focal disruptions of normal rhythms are more apparent

Question 9

A rare pattern that most commonly occurs in adults over the age of 50 in connection with hyperventilation

Answer 9

SREDA

Question 10

What syndrome is associated with slow spike-wave discharges, multiple seizures types, and generalized paroxysmal fast activity during sleep?

Answer 10

LGS