Embryogenesis Flashcards

1
Q

Cortical Reaction

A
  • Cortical granules fuse with oolemma

- Granules release contents (enzymes) between oolemma and zona pellucida

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2
Q

The prechordal plate is also known as:

A

Buccopharyngeal membrane

-site of future mouth development

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3
Q

How does the prechordal plate form?

A

Small, disk-like thickening of hypoblast forms at the end of hte bilaminar embryonic disk

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4
Q

What is the result of gastrulation?

A

Trilaminar empbryo whose 3 layers are the embryonic endoderm, mesodem, and ectoderm. All layers derive from the epiblast cells.

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5
Q

When does the definitive yolk sac form?

A

When the endodermal cells divide and migrate around the yolk sac, they gradually replace the original hypoblast cells.

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6
Q

What does the notochord induce?

A

Neural plate, neural groove formation in the overlying ectoderm

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7
Q

Mesoderm’s three main regions?

A

paraxial, intermediate, lateral.

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8
Q

What does lateral plate split into?

A

Visceral and parietal layers

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9
Q

Definite yolk sac becomes?

A

Primitive gut tube

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10
Q

Histogenesis

A

Cell movement from undifferentiated to producing many different layers of tissue

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11
Q

Spina bifida

A

Epidermis does not form completely

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12
Q

Derivatives of Ectoderm

A
Dorsal root ganglion
Sympathetic ganglia
Peripheral nerves
Schwann and satellite cells
Adrenal medulla
melanocytes
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13
Q

Derivatives of Mesoderm

A

Paraxial (somites-cartilage, bone, connective tissue of body and limbs)

Intermediate (Urogenital system)

Lateral Plate (Appendicular skeleton, tendons, ligaments, connective tissue of viscera and body wall)

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14
Q

Remnant of notochord

A

Nucleas polposus

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15
Q

(Paraxial) Somites Differentiation

A

Sclertotome- Cells migrate medially around notochord to form vertebral column

Dermatome: Cells migrate under ectoderm (epidermis) to form the dermis

Myotome: Cells divide into two groups, epaxial and hypaxial and form most skeletal muscles of the body

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16
Q

Long List– Derivatives of Ectoderm

A

Central Nervous System

  • Neurons of Brain and Spinal Cord
  • Glial cells of Brain and Spinal Cord
  • ——-Astrocytes
  • ——-Oligodendrocytes
  • ——-Ependymal cells

Epidermis and Derivatives
-Keratinocytes of Skin, Hair, and Nails

Ameloblasts (enamel-forming cells) of developing teeth

Epithelial cells lining the oral cavity and anal canal

Salivary gland epithelium
Secretory cells of the pituitary adenohypophysis
-Acidophils: Somatotrophs (Growth hormone); Lactotrophs (mammotrophs, prolactin)
-Basophils: Corticotrophs (ACTH); Gonadotrophs (FSH, LH); Thyrotrophs (TSH)
-Chromophobes: Follicular cells, Depleted & developing secretory cells

17
Q

Long List– Derivatives of Neural Crest

A

Peripheral Nervous System

  • Neurons of the peripheral nervous system
  • ——Ganglion cells
  • Supporting cells of the peripheral nervous system
  • ——Schwann cells & Satellite cells of ganglia

Adrenal medulla
-Chromaffin cells, Ganglion cells

Specialized cell populations of the epidermis
-Melanocytes, Merkel cells

Craniofacial (face & jaw) connective tissues
-All cells of developing teeth EXCEPT ameloblasts
——Odontoblasts , Cementoblasts, Pulp mesenchyme
Derivatives of craniofacial mesenchyme
——Craniofacial fibroblasts, osteoblasts, osteocytes, chondroblasts & chondrocytes

18
Q

Long List– Derivatives of Endoderm

A

Epithelial cells lining the digestive tract, from esophagus to rectum

  • Cells covering the intestinal surface: Enterocytes (absorptive cells), Goblet cells
  • Cells lining the intestinal crypts: Enterocytes, Goblet cells Paneth cells

Digestive glands that arise from digestive tract lining
-Liver: Hepatocytes
-Pancreas: Pancreatic acinar cells, Pancreatic alpha cells (glucagon), Pancreatic beta cells (insulin), Pancreatic delta cells (somatostatin)
Lining of ducts leading to digestive glands
Lining of bile ducts, gall bladder & cystic duct

Lining of pancreatic ducts
-Epithelial cells lining the respiratory tract from trachea to alveoli
Respiratory epithelium (pseudostratified ciliated columnar) lining trachea, larynx, & bronchi
-Simple ciliated columnar and cuboidal lining bronchioles, terminal bronchioles, respiratory bronchioles, and alveolar ducts
-Clara cells
-Type I (squamous) alveolar cells
-Type II alveolar (septal) cells

Specialized cell populations of digestive and respiratory tracts & pancreatic islets
-APUD (amine precursor uptake and decarboxylation) or DNES (diffuse neuroendocrine system)