Embryology Flashcards
The lower part of the vagina is formed by what?
The sinovaginal bulbs
The paroophoron is the residual remnant of what in males?
The mesonephric duct
What are the FSH independant steps of oocyte development?
- Mitotic oogonia (pre-natal)
- Germ cell nests (pre-natal)
- Meiosis (pre-natal)
- Birth
- Primordial follicles (post-natal)
- Growth (3-4 months)
From what are derived FEMALE genital ducts?
Paramesonephric ducts (Müllerian ducts)
What is a Gartner’s duct cyst?
A benign vaginal cyst which is a vestigial remnant of the mesonephric duct
The vaginal fornices and upper part of the vagina are formed from by what?
Paramesonephric duct
What genes and hormones are involved in the development of MALE gonads?
- SRY: encodes testis-determining factor (TDF) FROM THE Y CHROMOSOME
- SOX9: produced by SRY, inhibits WNT4
- Anti-Müllerian hormone (AMH): produced by Sertoli cells
- Testosterone: produced by Leydig cells
Gonads are derived from which 3 sources?
- Mesothelium (mesodermal epithelium) lining the posterior abdominal wall
- Underlying mesenchyme (embryonic connective tissue)
- Primordial germ cells
The ovarian ligament and the oround ligament of the uterus are derived from which embryologic tissue?
The gubernaculum
What happens during the growth of the oocyte?
- All oocyte begin to grow 3-4 months before their ovulation
- The signal to begin growth is given by granulosa cells with the help of a growth factor that binds to a growth receptor which enhance protein synthesis
The appendix testis is the final remnant of what?
The paramesonephric duct
What is the male homologue of the epoophoron?
The epididymis
What cells are absolutely important for the growth of the oocyte?
Granulosa cells
When do the FEMALE gonads develop?
12th week
From what are derived MALE genital ducts?
Mesonephric ducts (Wolffian ducts)
