Embryology of the GI System Flashcards Preview

GI Midterm > Embryology of the GI System > Flashcards

Flashcards in Embryology of the GI System Deck (24):
1

Molecular development of gut tube

initiated by transcription factors expressed in different regions of the tube

2

Development of Esophagus

laryngetotracheal diverticulum of foregut into the surrounding splanchnic mesoderm

3

Development of Stomach

dilation of foregut
Dorsal surface grows faster
Left moves anterior after 90 degree rotation

4

Development of Liver

in ventral mesentery
development is blocked everywhere
cardiac region inhibits the blocking which allows liver development

5

Development of Gallbladder and bile duct

in ventral mesentery
hepatic cords coalesce around exraembryonic veins to make sinusoids
bile duct forms
gallbladder and cystic duct are outgrowths of bile duct

6

Development of Pancreas

both ventral and dorsal mesentery
PDX 1 - pancrease and duodenum
PDX 4 - endocrine function

7

esophageal stenosis or atresia

narrowed or occluded esophagus

8

hypertrophic pyloric stenosis

overgrowth
not immediately after birth
projectile vomiting of non bile

9

duodenal atresia and stenosis

upper - no recanalization
lower - vascular compromise

10

extrahepatic biliary atresia

bile ducts dont completely open
jaundice
dark urine
pale stool

11

annular pancreas

anterior and posterior pancreas form ring around duodenum
presents as duodenal obstruction

12

accessory or ectopic pancreatic tissue

most common in stomach or ileum

13

apple peep atresia

occurs at proximal jejunum
short intestine due to proximal part being in a coil

14

rotation of the foregut

stomach moves left
liver moves right
peritoneal cavities change size
R side gets smaller

15

Rotation and fixation of midgut

rapid growth of midgut produces normal physiologic herniation
gut loops out into the umbilical cord and rotates 90 degrees
after 10 weeks loop returns to abdominal cavity and rotates another 180 degrees

16

malroation

abnormally positioned visera
risk for entrapment

17

volvulus

abnormal twisting of intestine causing obstruction

18

intussusception

enfolding of one segment of intestine within another

19

omaphalocele

gut herniation and covered by membranous sac
midgut fails to return to abdominal cavity

20

gasroschisis

anterior abdominal wall musculature to close during folding
gut herniation not covered by membranous sac
more frequent in younger women who use cocaine

21

prune belly syndrome

anterior abdominal wall musculature is deficient or absent
urinary tract anomalies
bilateral cryptorchidism
most common in males
failed mesoderm development

22

ileal diverticulum

meckel's diverticulum
failure of the vitelline duct to close

23

enteric neurons plexi

myenteric plexus - develops 1st and occupies a postion b/w longitudinal and circular mm layers
submucosal plexus - forms later in gestation and resides w/in submuucosa

24

hirschsprung's disease

both enteric plexus are affected
myenteric is more effected
no movement of mm so bowel is obstructed