ENDO

Question 1

ORGAN OF ENDO SYSTEM?

Thyroid releasing hormone (TRH) & Corticotropic releasing hormone (CRH)

Answer 1

Hypothalamus

Question 2

ORGAN OF ENDO SYSTEM?

PTH

Answer 2

Parathyroid

**4 parathyroid glands located behind the thyroid

Question 2

ORGAN OF ENDO SYSTEM?

TSH, FSH, LH, Oxytocin, ADH

Answer 2

Pituitary Gland

**located in brain, b/w eyeballs

Question 3

ORGAN OF ENDO SYSTEM?

Glucocorticoids, Mineralocorticoids (Aldosterone), Sex hormones

Answer 3

Adrenal Cortex

Question 4

ORGAN OF ENDO SYSTEM?

Insulin, Glucagon

Answer 4

Pancreas

Question 5

ORGAN OF ENDO SYSTEM?

T3, T4, Calcitonin

Answer 5

Thyroid Gland

Question 6

ORGAN OF ENDO SYSTEM?

Catecholamines (E & NE)

Answer 6

Adrenal Medulla

Question 7

Thyroid hormones & TSH has a _________ (direct/inverse) relationship

Answer 7

Inverse

if T3 & 4 inc, TSH dec

Question 8

PTH & Ca has a ______ (direct/inverse) relationship

Answer 8

Direct

PTH increases Ca

Question 9

Calcitonin _____ (inc/dec) Ca

Answer 9

Decreases

**inhibits osteoclast activity = dec Ca release

Question 10

Insulin _____ (inc/dec) glucose while glucagon _______ (inc/dec) glucose

Answer 10

Decreases

Increases

**glucagon causes glycogenolysis in liver

Question 11

INSULIN STORAGE

1. Keep away from _____ & direct ______
2. NEVER ______ insulin
3. Store in ________ until ready for use
4. If using, keep in ______ temp

Answer 11

1. heat & direct sunlight
2. freeze
3. refrigerator
4. room

Question 12

only insulin that is cloudy

Answer 12

NPH

Question 13

only insulin given via IV

Answer 13

regular

Question 14

Mneumonic for order drawing up NPH & Regular

Answer 14

“N-R-R-N”

N-R = injecting air in vial order
R-N = drawing up vial order

Question 15

Never mix what type of insulin with others?

Answer 15

Glargine (long acting)

Question 16

In Addison’s dse, s/sx are ________

Answer 16

LOW

fatigue, bronze skin, hypogly, wt. LOSS, DHN, hypotension

Question 17

Addisonian Crisis S/SX:

Answer 17

Shock & Hypoglycemia

Question 18

Na & K levels in Addisons Dse?

Answer 18

HYPOnatremia: d/t dec aldosterone (regulates H2O & Na retention)

HYPERkalemia: d/t dec cortisol (causes inc ADH & retains K)

Question 19

Tx of Addisons:

1. ______ administration
2. Replace _________

Answer 19

1. Isotonic IV fluid
2. Steroids

Question 20

Dse where there is an under-secretion of adrenal cortex

Answer 20

Addisons

Question 21

Dse where there is an over-secretion of adrenal cortex

Answer 21

Cushings

Question 22

Na & K levels in Cushings?

Answer 22

HYPERnatremia

HYPOkalemia

Question 23

In cushings, every s/sx are _______

Answer 23

HIGH

Hyperglycemia, irritable, Fluid retention, immunosuppressed

Question 24

Cushings Tx: 1. Surgery? 2. Avoid _____

Answer 24

1. Adrenalectomy: monitor BP & electrolytes 2. infection

Question 25

Dse caused by a TUMOR on adrenal gland that causes OVERPRODUCTION of ALDOSTERONE aka Primary aldosteronism

Answer 25

Conn's dse **tumor = too much

Question 26

S/sx of Conn's?

Answer 26

HYPER-Na & HTN HYPO-K

Question 27

Tx of Conns dse?

Answer 27

Tumor Removal

Question 28

Can you palpate the abdomen of a pt with Pheochromocytoma?

Answer 28

NO! Can stimulate catecholamine release

Question 29

Dse caused by a TUMOR on adrenal gland that causes OVERPRODUCTION of CATECHOLAMINES

Answer 29

Pheochromocytoma

Question 30

Tx of Pheochromocytoma? (med & sx)

Answer 30

alpha & beta adrenergic blockers for HTN Adrenalectomy

Question 31

Dse where there is NOT ENOUGH ADH in the body

Answer 31

DI

Question 32

Complications of DI?

Answer 32

Shock & FVD

Question 33

S/Sx of DI?

Answer 33

Polyuria, polydipsia

Question 34

in DI: Urine is ____ Blood is _____

Answer 34

diluted (dec USG, URINE osmolarity) concentrated (inc Na, SERUM osmolarity & Hct>40)

Question 35

Nx for DI: 1. Monitor ____ (what v/s) 2. ______ Fluids (inc/dec) 3. What drug to give

Answer 35

1. Neuro status 2. Inc fluids 3. Vasopressin/desmopressin

Question 36

Dse where there is an OVERPRODUCTION of ADH in the body

Answer 36

SIADH

Question 37

in SIADH,