Endo Flashcards

(87 cards)

1
Q

treat pcos

A

pill cyprotetorne acetate

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2
Q

what are the three types of ovulation disorders?

A

hypothalamic pituitary - pcos hypothalamic ovarian

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3
Q

increased pth decreased ca increased phosphate

A

pseudohypoparathyroidism

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4
Q

hyperthyroid oatient in 1st trimester of preg

A

propyuracil

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5
Q

what is pseudohypoparathyroidism

A

resistance to pth

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6
Q

t4

A

dit and dit

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7
Q

t3/4 high tsh low

A

primary hyperthyroid

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8
Q

autoimmune hyperthyroid

A

graves

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9
Q

diagnose di

A

water deprivation test

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10
Q

what is dka

A

insulin deficiency then an increase in counter regulatory hormones

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11
Q

t3/4 high tsh high

A

secondary hyperthyroid

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12
Q

treat dka

A

insulin potassium and glucose

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13
Q

follicular cells secrete ….

A

thyroglobulin

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14
Q

autoimmune hypothyroid

A

hashimoto

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15
Q

give what drug in mody

A

sulphonylureas

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16
Q

what is primary hyperparathyodi

A

overactive gland

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17
Q

t1 autoantibodies

A

anti gad and anti islet cell

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18
Q

zona glomerulosa

A

aldosterone (raas)

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19
Q

which thyroid nodule spreads via lymphatics

A

papillary

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20
Q

what is primary aldosteronism

A

adrenal hyperplasia and conns (tumour of xona glomerulsoa)

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21
Q

low t3/4 low tsh

A

secondary hypothyroid

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22
Q

diagnose diabetes on

A

fasting glucose

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23
Q

what moves on swallowing

A

thyroglossal duct cyst

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24
Q

what are the two types of cushings

A

actg dependent - adenoma in pituitary acth independent - adrenal carcinoma/ malignancy (lung/ thymus) / exogenous steroids

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25
parafollicular cells secrete
calcitonin
26
which thyroid nodule spreads haematogenously
follicular
27
eg ddp4i
gliptin
28
what is hhs
hypovolaemia glucose \>30 hyperosmolar \>320
29
very very low thyroid hormones
myxoedema
30
diagnose adrenocortical hypofunction
short synacthen
31
diagnose cushings
low dose dexamethasone
32
treat addisons crisis
IV hydrocortisone IV saline IV sliding scale insulin
33
treta hypothyroid
levothyroxine
34
diagnose primary aldosteronis
saline suppression test
35
medulla
catecholamines ( sympathetic ns)
36
treat siadh
fluid restriction and tolvaptan
37
what is siadh
adh secreted in response to a non osmoic stimulus causing water retention
38
treat adrenocortical hypofunction
hydrocortisone and flurocortisone
39
low t3/4 high tsk
primary hypothyroidism
40
what is pcos
high testosterone high lh insulin resistance
41
zona reticularis
sex hormones (androgens)
42
treat hypoparathyroid
ca and vit d
43
what secretes the catecholamines in phaeochromocytoma
chromaffin cells
44
in phaechromocytoma what should you screen for
check the thyroid in case of men 2
45
t3
mit and dit
46
biochem in addissons
low na low h20 high k hypotension
47
acromegaly
gh excess in adults
48
treat cushings
metyrapone +/- ketoconazole
49
diabetes is diagnosed with a fasting glucose over
7
50
treat hyperthyroid
carbimazole
51
treat HHS
K and may need insulin
52
autoantibodies in hashimoto
anti tpo
53
what diabetic drugs can you use in pregnancy?
metformin and insulin
54
gigantism
gh excess in kids
55
treat a high prolactin
bromocriptine quinagolide cabergoline
56
diabetes is diagnosed with a random glucose over
11.1
57
what is secondary hyperparathyroid
physiologicalresponse to low ca
58
treat psuedohypopatathryroidism
ca and vit d suppl
59
men 2
medullary thyroid parathyroid phaeochromoytoma
60
what is a phaeochromocytoma
catecholamine secreting tumour
61
hba1c in diabetics
48\>
62
diagnose addisons
short synacthen
63
transcription factor mutations in diabetec
diabetes at later stage in life
64
eg sglt2
dapagliflozin
65
pth high calcium high
primary hyperparathyroid or tertiary
66
what is the biochem like in primary aldosteronism
high nacl high h20 hypertension and hypokalakaemia
67
what is di
lack of adh so kidneys cant reabsorb water so na increases
68
which thyroid nodule secretes melatonin
medullary
69
treat primary alodsteronism
spironolactone
70
men 1
pituitary adenoma parathyroid hyperplasia pancreatic tumours
71
c peptide is absent in
type 1 diabetics but present in type 2
72
eg sulphonylurea
glicazie
73
what is addisons disease?
primary adrenal insufficiency with autoimmune destruction of the adrenal cortex
74
pth high ca lo
secondary hyperparathyroid
75
what is tertiary hyperparathyroidism
many years of secondary
76
treat addisons
hydrocortisone
77
zone fasciculata
cortisol (acth)
78
where is a craniopharyngioma usually
rathkes pouch
79
treat phaechromoxytoma
alpha (phenoxybenzamine) then beta (propranolol) blockade
80
very very very high thyroid hormoens
thyrotoxicosis
81
treat gh excess
pegvisomant (also cabergoline if secreting prolactin or octreotide)
82
ovulation induction in pcos
clomifene citrate and metformin
83
diagnose gh excess
oral glucose tolerance test
84
treat hypocalcaemia
iv calcium gluconate 10ml 10% over 10mins
85
what is diagnostic of dk a
ketones\>3 glucose \>11 ph \<7.3
86
glucokinase mutation
altered glut 2 - glucose higher than norma l
87
treat di
desmopressin