Endo Treatment

Question 1

Treatment for acromegaly

Answer 1

tumor resection

Question 2

Tx for papillary thyroid cancer?

Answer 2

surgery then if stage 3 or 4 do radioactive iodine

Question 3

How do you treat adrenal crisis?

Answer 3

hydrocortisone

Question 4

What is treatment for central diabetes insipidus?

Answer 4

Desmopressin

Question 5

Tx for pheochromocytoma

Answer 5

alpha blockade followed by beta blockade to lower BP

then once BP controlled laptoscopic adrenalectomy

Question 6

Treatment for graves dz

Answer 6

Methimazole to stop TH production and then thyroidectomy or radioactive iodine ablation

once thyroid is taken out will need levothyroxine later one because will be hypothyroid

Question 7

After starting a patient on levothyroxine when should you check their labs?

Answer 7

4-6 weeks

Question 8

Treatment for pregnant patient with Graves disease

Answer 8

PTU

Question 9

Treatment for thyroid storm

Answer 9

steroids

Question 10

What are long acting insulin therapy choices that can be used for basal rate?

Answer 10

Glargine or Detemir

Question 11

What are short acting insulin therapies that can be used for bolus?

Answer 11

lispro
aspart
glulisine

Question 12

Hypothyroidism tx

Answer 12

give T4 (body will convert to T3)

Question 13

Octreotide class

Answer 13

Somatostatin analog

Question 14

Lanreotide class

Answer 14

Somatostatin analog

Question 15

Desmopressin (DDAVP) class

Answer 15

Anti-Diuretic Hormone (synthetic)

Question 16

Spironolactone class

Answer 16

Potassium-sparing Diuretics

Question 17

Eplerenone class

Answer 17

Potassium-sparing Diuretics

Question 18

Levothyroxine class

Answer 18

Thyroid Hormone (synthetic)

Question 19

Methimazole class

Answer 19

Thyroid Hormone Synthesis Inhibitor

Question 20

If you have low TOTAL calcium what do you have to make sure to correct?

Answer 20

low albumin

Question 21

Diabetes glycemic control targets

Answer 21

HbA1C <7%, pre-prandial capillary glucose 80-130, peak post-pranial glucose <180

Question 22

What does U 100 mean?

Answer 22

100 units of insulin per mililiter

Question 23

What are the rapid acting insulin drugs?

Answer 23

Lispro
Aspart
Glulisine

Question 24

What are the long acting insulin drugs?

Answer 24

Glargine
Detemir
Degludec (very long)

Question 25

What are the intermediate acting insulin drugs?

Answer 25

NPH

Question 26

How much insulin is required daily?

Answer 26

0.6-0.7 units/kg

Question 27

SOA of alpha-Glucosidase inhibitors

Answer 27

GI tract dec carb absorption

Question 28

SOA of metformin

Answer 28

liver dec glucose production

Question 29

SOA of GLP-1 agonist | and DPP-4 inhibitor

Answer 29

GI tract | and increases insulin secretion at pancreas

Question 30

SOA of Sulfonylureas, Meglitinides and Nateglinide

Answer 30

Pancreas- increases insulin secretion

Question 31

SOA of Glitazones

Answer 31

muscle and fat increases glucose uptake

Question 32

SOA of SGLT2 inhibitor

Answer 32

kidney increases glycosuria

Question 33

SE GLP1

Answer 33

weight loss

Question 34

SE of insulin

Answer 34

wt gain

Question 35

Metformin SE

Answer 35

GI SE | contraind w/ GFR <30

Question 36

DPP4 SE

Answer 36

risk of acute pancreatitis | renal dose adj-for Januvia®, Nesina®, Onglyza®

Question 37

SGLT-2 Inhibitors renal considerations

Answer 37

Decreased efficacy as GFR | decreases, not recommended with GFR <30-60

Question 38

SGLT-2 Inhibitors SE

Answer 38

Risk of DKA (class effect) Genitourinary infections Risk of volume depletion Increased LDL cholesterol

Question 39

Pioglitazone BBW

Answer 39

CHF also has risk of bone fx and bladder ca

Question 40

What oral agent should you avoid in patients with high HbA1C?

Answer 40

DPP-4 inhibitor

Question 41

What are the injectables for DM treatment?

Answer 41

GLP1 RA and insulin

Question 42

GLP1 RA SE

Answer 42

BBW medullary thyroid ca GI SE

Question 43

How should you change insulin dose as GFR decreases?

Answer 43

Lower insulin doses as GFR | decreases due to increased risk of hypoglycemia

Question 44

Tx of primary hyperparathyroidism

Answer 44

surgery

Question 45

What do you need to warn pts about when taking Levothyroxine

Answer 45

Do not take within 1 hr of food or 4 hrs of calcium or iron