endocine

Question 1

how does rhizophus presnet

Answer 1

unilateral maxillofacial infection with retro-orbital headache, facial pain, nasal discharge, and fever

Question 2

how is insulin resistance caused

Answer 2

Activation of serine kinases is a key molecular mechanism in the development of insulin resistance. These kinases inactivate insulin receptor substrate (IRS) protein function through phosphorylation, reducing the action of phosphatidylinositide 3-kinases, thereby blocking downstream signaling of insulin receptors. In addition, serine kinases are able to phosphorylate serine residues on the insulin receptor itself,

Question 3

what is pathogensis of diabetic neuropathy

Answer 3

. Chronic hyperglycemia leads to the formation of nonenzymatically glycosylated plasma and tissue proteins, which leads to hyalinization of the basal lamina and thickening of the basement membrane of endoneural vasculature. As a result, nerve ischemia occurs, leading to a reduction of intraepidermal nerve fiber densit