Endocrine Flashcards

(46 cards)

1
Q

3 most common causes of polyuria/polydipsia in cats?

o chronic kidney disease, diabetes mellitus, hyperthyreosis
o hyperthyreosis, diabetes mellitus, bacterial cystitis
o bacterial cystitis, diabetes insipidus, hyperthyreosis
o chronic kidney disease, bacterial cystitis, diabetes mellitus

A

chronic kidney disease, diabetes mellitus, hyperthyreosis

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2
Q

3 most common causes of polyuria/polydipsia in dogs

o pyometra, bacterial cystitis, diabetes mellitus
o chronic kidney disease, Cushing syndrome, diabetes mellitus
o Cushing syndrome, diabetes mellitus, pyometra
o bacterial cystitis, Cushing syndrome, diabetes mellitus

A

o chronic kidney disease, Cushing syndrome, diabetes mellitus

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3
Q

What is the target blood glucose level in the diabetic patient at maximum effect of insulin?

o 3-6 mmol/l
o 3-6 umol/l
o 4-9 umol/l
o 4-9 mmol/l

A

4-9 mmol/l

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4
Q

Causes of insulin resistance:

o progesterone, hypercortisolism, hypersomatotropism
o hypocalcemia, glucocorticoids, acromegaly
o cushing’s syndrome, enalapril, progestagens
o acromegaly, xilitol, cushing’s syndrome
o MPA, DOCP, GH

A

progesterone, hypercortisolism, hypersomatotropism

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5
Q

What may cause hypoglycemia in the diabetic patient treated with insulin?

o	Progestagen treatment 
o	Concurrent diabetes insipidus
o	Castration of male dog/cat
o	Neutering the bitch after 2-5 days 
o	Stress 
o	Glucocorticoid therapy
A

o Progestagen treatment

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6
Q

What may cause hypoglycaemia in the diabetic patient treated with insulin?

o Progestogen treatment
o Concurrent diabetes insipidus
o Castration of male dog/cat
o Anorexia, vomiting

A

o Progestogen treatment

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7
Q

What may cause hyperglycemia in the diabetic patient treated with insulin?

o	liver failure
o	concurrent addison’s disease
o	insulin resistance 
o	Xylitol-toxicosis
o	neutering bitch after 2-5 days
A

o insulin resistance

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8
Q

• Which statement is true? In monogastric animals the energy content of dietary….

o proteins is utilized most efficiently
o carbohydrates is utilized most efficiently
o fibers is utilized most efficiently
o fats is utilized most efficiently

A

fats is utilized most efficiently

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9
Q

Breed NOT predisposed for obesity?

o Labrador retriever
o Borzoi
o Dachshund
o Beagle

A

o Borzoi

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10
Q

Which is NOT a possible consequence of obesity?

o Hypertension (dog)
o Type-2 diabetes mellitus (cat)
o Hypokalemi
o Hyperlipidemia

A

o Hypokalemi

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11
Q

Treatment of obesity - which of the below statements is true?

o Commercial BW reduction diets are not recommended in cats, because they increase the risk of hepatic lipidosis
o Commercial BW reduction diets are useful because with reduced energy intake, the feeling of satiety is easily achievable
o Commercial BW reduction diets are useful, because without, BW reduction is not achievable
o Commercial BW reduction diets are not recommended, because they do not increase sufficiently the daily energy expenditure

A

o Commercial BW reduction diets are useful because with reduced energy intake, the feeling of satiety is easily achievable

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12
Q

Pathophysiology of obesity - which of the below statements is true?

o Hyperplastic obesity occurs mainly in growing animals
o Prognosis is good in hyperplastic obesity, because the stationary phase quickly replaces the dynamic phase
o Prognosis is careful in hypertrophic obesity, because the dynamic phase quickly replaces the stationary phase
o In hypertrophic obesity the size and the number of adipocytes increases

A

o Hyperplastic obesity occurs mainly in growing animals

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13
Q

“Fat-dervied peptides”/Effects of cytokines and hormones produced by adipocytes?

o Mild chronic inflammation, decrease in insulin resistance
o Increase in appetite, decrease in insulin resistency
o Mild chronic inflammation, long-lasting oxidative stress
o Mild acute inflammation, increase in blood pressure, increase in appetite

A

o Mild chronic inflammation, long-lasting oxidative stress

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14
Q

What is ‘endotoxin’?

o Lipoprotein molecule produced by Gr+ bacteria
o Lipoprotein molecule produced by Gr- bacteria
o Lipopolysaccharide molecule in the cell wall of Gr+ bacteria
o Lipopolysaccharide molecule in the cell wall of Gr- bacteria

A

o Lipopolysaccharide molecule in the cell wall of Gr- bacteria

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15
Q

Which endocrine disease is characterized by the following plantigrad movement?

o Addison disease
o Hyperthyroidism
o Diabetes insipidus
o Diabetes mellitus

A

o Diabetes mellitus

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16
Q

Diabetes insipidus, which is correct:

o Clinical manifestation PD/PU, hypersthenuria
o The most effective drug in the central form is desmopressin
o The ADH production of the kidney is insufficient in the nephrogenic form
o Diagnosis; modified water deprivation test, ADH- stimulation test

A

o The most effective drug in the central form is desmopressin

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17
Q

In which endocrine disorder there is NO polydipsia/polyuria?

o	Diabetes mellitus
o	Diabetes insipidus
o	Hypothyroidism
o	Cushing's syndrome
o	Hyperthyroidism
A

o Hypothyroidism

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18
Q

Hypothyroidism of dogs: diagnosis

o Thyroxine↓ and TSH ↑, free thyroxine ↑, TGAA -, TRH-stimulation test
o Thyroxine ↓ and TSH ↑, free thyroxine ↓, TGAA , TSH-stimulation test
o Thyroxine ↓ and TSH ↑, free thyroxine ↓, TGAA, ACTH-stimulation test
o Thyroxine ↑ and TSH ↓, free thyroxine ↓, TGAA, ACTH-stimulation test

A

o Thyroxine ↓ and TSH ↑, free thyroxine ↓, TGAA , TSH-stimulation test

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19
Q

Hypothyroidism of dogs: symptoms

o activity ↓, obesity, PD/PU, alopecia, tachycardia, fertility↓
o activity ↑, obesity, alopecia, thick skin, bradycardia, PP
o activity ↓, obesity, alopecia, thin skin, bradycardia, fertility↓
o activity ↓, weight gain, alopecia, thick skin, bradycardia fertility ↓

A

o activity ↓, weight gain, alopecia, thick skin, bradycardia fertility ↓

20
Q

Which statement is correct?

o hyperthyroidism caused by thyroid adenoma is common in cats
o hypothyroidism caused by thyroid adenoma is common in cats
o hyperthyroidism caused by thyroid adenocarcinoma is common in cats
o hypothyroidism caused by thyroid adenocarcinoma is common in cats

A

o hyperthyroidism caused by thyroid adenoma is common in cats

21
Q

Hyperthyroidism of cats: therapeutic options

o thyoridectomy, radiotherapy, methimazole, iodine diet
o parathyroidetomy, 131I IV, methimazole, low iodine diet
o thyroidectomy, 99TC IV, methimazole, low sodium diet
o parathyroidectomy, 131I IV, fenbendazole, low iodine diet

A

o thyoridectomy, radiotherapy, methimazole, iodine diet

22
Q

Hyperthyroidism of Cats

o Consequence of thyroiditis, goiter, dyspnoe, dilated cardiomyopathy
o Consequence of thyroid gland tumor, goiter, myxedema, anorexia/cachexia
o Consequence of thyroiditis, aggressivity, panting, sudden blindness due to hypotension
o Thyroid adenoma or hyperplasia, polyphagia, weight loss, myocardial hypertrophy

A

o Thyroid adenoma or hyperplasia, polyphagia, weight loss, myocardial hypertrophy

23
Q

What condition does this dog have?

o Hypothyroidism (alopecia)
o Hyperthyroidism
o Cushing’s syndrome
o Diabetes mellitus

A

o Hypothyroidism (alopecia)

24
Q

Which statement is correct regarding anesthesiologic considerations of hypothyreoidism

o Due to thermoregulatory imbalance hyperthermia occurs
o The overall metabolic rate is decreased, drug metabolism is slower, therefore the “vulnerability” of the patient to anesthesia is lower
o Myocardial contractibility is decreased, tachycardia is present
o Obesity results in a limited range of motion of the diaphragm

A

o Obesity results in a limited range of motion of the diaphragm

25
Clinical features of congenital hyposomatotropism: o Yorkshire terrier, pituitary tumor, liver failure, alopecia o German shepherd, proportionate dwarfism, alopecia o Great Dane, enzyme deficiency, kidney failure o Beagle, IGF-1↓, disproportionate dwarfism
o German shepherd, proportionate dwarfism, alopecia
26
This picture is characteristic for (pomeranian med lite pels på ryggen) ``` o demodicosis o hyperthyroidism o alopecia-X o cushing’s disease o color dilution alopecia ```
o alopecia-X
27
Which statement is false? Following neutering... o the Basic Metabolic Rate is reduced. o the appetite may increase. o ...the physical activity may decrease o ...the production of the anabolic hormone, melatonin is increased.
o ...the production of the anabolic hormone, melatonin is increased.
28
In which endocrine disorder there is no polydipsia/polyuria? ``` o Diabetes mellitus o Diabetes insipidus o Alopecia-X o Cushing's syndrome o Hyperthyroidism ```
o Alopecia-X
29
Acromegaly: cause o Dog: pituitary tumor, cat: estrogen treatment, mammary gland tumor, ovarian cyst o Aquired GH deficiency in adults o Congenital GH excess o Dog: progestagen treatment, Cat: pituitary tumor
o Dog: progestagen treatment, Cat: pituitary tumor
30
Acromegaly, causes? o Dog: pituitary tumour, Cat: oestrogen treatment, mammary gland tumour, ovarian cyst o Acquired GH deficiency in adults o Congenital GH excess o Dog: progestogen treatment, mammary gland tumour, ovarian cyst, Cat: pituitary tumour
Dog: progestogen treatment, mammary gland tumour, ovarian cyst, Cat: pituitary tumour
31
Acromegaly treatment? | o Ovariehysterectomy
Ovariehysterectomy
32
Which of the followings is the “classic" indication of adrenalectomy? o unilateral adrenal cortical adenoma caused periferial Cushing's disease o unilateral adrenal cortical adenoma caused central Cushing's disease o unilateral adrenal medullar adenoma caused periferial Cushing's disease o unilateral adrenal medullar adenoma caused central Cushing's disease
o unilateral adrenal cortical adenoma caused periferial Cushing's disease
33
Diabetes insipidus: Which is correct? o Clinical manifestations: PD/PU, hypersthenuria o The most effective drug in the central form is desmopressin o The ADH production of the kidneys is insufficient in the nephrogenic form o Diagnosis: modified water deprivation test, ADH-stimulation test
o The most effective drug in the central form is desmopressin
34
Which statement is TRUE regarding diabetes insipidus? o partial or complete ADH deficiency o failure of the renal tubules to react ADH (begge er riktig? ene er central andre er Nephrogenic) o very common disorder o in case of water deprivation these patients are able to concentrate there urine
o partial or complete ADH deficiency
35
Breed predisposed for Addison's disease ``` o French bulldog o Irish setter o Poodle o Dachshund o Beagle ```
o Poodle
36
Addison's disease in Dogs: causes, pathogenesis o The primary disease is due to autoimmune inflammation of the adrenals o Primary: cortisol↑, aldosterone↓ Secondary: cortisol↓, aldosterone ←→ o The primary disease is due to incorrect glucocorticoid therapy o Primary: cortisol↓, aldosterone↓ Secondary: cortisol ←→ ,aldosterone↓
o The primary disease is due to autoimmune inflammation of the adrenals
37
Addison's disease in dogs/causes, pathogenesis: o The primary is due to auto-immune inflammation of the adrenals. The secondary disease is caused by incorrect glucocorticoids therapy o Primary: Cortisol ↑ Aldosterone ↓ Secondary: Cortisol ↓ Aldosterone same o The primary disease is due to incorrect glucocorticoid therapy. The secondary disease is caused by auto-immune inflammation of the adrenals o Primary: Cortisol ↓ Aldosterone ↓ Secondary: Cortisol same Aldosterone ↓
o The primary is due to auto-immune inflammation of the adrenals. The secondary disease is caused by incorrect glucocorticoids therapy
38
Addison's disease in Dogs: diagnosis o Na /K >27, CI- ↓, ACTH-stimulation test o Na /K <27, CI- ↓, ACTH-stimulation test o Na /K <27, C- ↓, LDDST o Na /K <27, CI- ↑, LDDST
o Na /K <27, CI- ↓, ACTH-stimulation test
39
Hypoadrenocorticism: o Primary cortisol decreased, aldosterone decreased o Primary cortisol increased, aldosterone decreased o Primary cortisol decreased, aldosterone increased o Primary cortisol increased, aldosterone increased
o Primary cortisol decreased, aldosterone decreased
40
Hypoadrenocorticism of dogs: clinical manifestations o dehydration, K inc, Ca dec, weakness, tremor, shock o dehydration, Na inc, K dec, abdominal pain, PD/PU o dehydration, K inc, Cl- dec, shock, bradycardia o vomiting/diarrhea, K dec, Ca dec, shock, tetant
o dehydration, K inc, Cl- dec, shock, bradycardia
41
Hypoadrenocorticism of Dogs: therapy o Crisis: 0.9% saline, hydrocortisone Later: fludrocortisone, DOCP, prednisolone, salt o Crisis: 0.09% saline, DOCP, hydrocortisone Later: fludrocortisone, prednisolone, salt o Crisis: 0.9% saline, hydrocortisone Later: DOCD, prednisolone o Crisis: 0.9% saline, fludrocortisone Later: hydrocortisone, DOCP, prednisolone, salt
o Crisis: 0.9% saline, hydrocortisone Later: fludrocortisone, DOCP, prednisolone, salt
42
Hypoadrenocorticism of dogs: therapy? o Crisis: 0.9% saline, hydrocortisone, Later: fludrocortisone, prednisolone, salt o Crisis: 0.09% saline, hydrocortisone, Later: fludrocortisone, prednisolone, salt o Crisis: 0.9% saline, hydrocortisone, Later: progesterone, prednisolone o Crisis: 0.9% saline, fludrocortisone, Later: hydrocortisone, prednisolone, salt
o Crisis: 0.9% saline, hydrocortisone, Later: fludrocortisone, prednisolone, salt
43
Which breed predisposed for Cushing’s syndrome? ``` o greyhound o cocker spaniel o english bulldog o karelian beardog o dachshund ```
o dachshund
44
What is the pathognomonic symptom of Cushing’s syndrome? ``` o Collarette o hyperhidrosis o angioedema o keratin plugs o calcinosis cutis ```
o calcinosis cutis
45
Cushing's Syndrome in dogs: diagnosis? o Confirmation: HDDST, ACTHST, Differentiation of forms: abdominal US, LDDST, ACT o Confirmation: LDDST, ACTH ST, Differentiation of forms: abdominal US, HDDST, ACTH o Confirmation: LDDST, ACTH ST, Differentiation of forms: X-ray, HDDST, ACTH o Confirmation: abdominal US, HDDST, Differentiation of forms: LDDST, ACTHST
o Confirmation: LDDST, ACTH ST, Differentiation of forms: abdominal US, HDDST, ACTH
46
• This picture is characteristic for (white dog, poor skin condition) ``` o Neoplasma abdominis o Protein losing enteropathy o Alopecia-X o Hypercortisolism o Right-side heart failure ```
o Hypercortisolism