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Flashcards in Endocrine Deck (18)
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1

Which insulin do you give once a day?

basal (long acting) eg lantus

2

Which diabetic drug is weight neutral?

DPP4 inhibitors eg sitagliptin

3

What is strawberry milkshake coloured blood?

hyperlipidaemia

4

What are the calcium, phosphate and alkaline phosphate levels in Paget's disease?

normal calcium and phosphate, high alkaline phosphate

5

Which hormone tests for pregnancy?

HCG

6

Which hormone peaks before ovulation?

LH (about 12 hrs before)

7

Which hormone is used to test for fertility?

progesterone

8

Which is Paget's?

increased osteoclastic reabsorption followed by increased osteoblastic activity

9

Key words for Paget's?

family history, male, old age, FH, bone pain (pelvis, lumbar spine, femur)

10

What is Pagets linked to?

deafness, cardiac failure, fractures, skull thickening

11

What is osteomalacia in children?

rickets

12

What are the calcium, phosphate and alk, phosphate levels in osteomalacia?

low calcium and phosphate
high alk,phosphate

13

What happens to bone in osteomalacia?

abnormal softening of bone due to mineralization of osteoid (immature) bone

14

Causes of osteomalacia?

malabsorption, poor diet or lack of sunlight

15

Symptoms/signs of osteomalacia?

bone pain, tenderness, fractures (especially femoral neck), proximal myopathy, waddling gait

16

Treatment of Paget's?

bisphosphonate (risedronate)

17

Treatment of osteomalacia?

vit D therapy
with calcium and phosphate supplements

18

Key words - bony metastases..?

high calcium
osteoclast formation
bone pain