endocrine Flashcards
What is the most common form of hypothyroidism?
Hashimoto thyroiditis-autoimmne
What is most common form of hyperthyroidism?
Graves’
Where should TSH be kept if on treatment?
0.5-1.5
What is the starting dose for levothyroxine?
1.6mcg/kg/d in adults-approx 50mcg/d
What is subclinical hypothyroid?
elevated TSH with normal T4–treat if goiter or antibodies
What lab values indicate DM?
fasting glucose >126, random glucose >200, A1c>6.5
What lab values indicate impaired fasting glucose?
fasting glucose 100-125, A1c 5.7-6.4
What is first line treatment for T2DM?
biguanide-insulin sensitizer
what is mechanism of action for sulfonylureas?
increase insulin release
What are examples of DPP4 inhibitors?
gliptins–januvia, onglyza
What is the mechanism of action in DPP4s?
Increase insulin release post meal
What are the incretin mimetics/GLP1 (Glucagon-like peptide) agonists?
injectables: bydureon, Byetta, Victoza
How do GLP1 agonists work
Increase insulin release post meal, slows gastric emptying, can lead to weight loss
what drug class can increase yeast infections?
SGLT2s (selective sodium-glucose transporters) invokana, farxiga, jardiance
what is the shortest acting insulin?
humalog, novolog
