Endocrine Control/Review Flashcards

(49 cards)

0
Q

what is a temporary endocrine gland?

A

placenta

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1
Q

Hormone is borne where? acts where?

A

blood borne
comes from endocrine glands
acts on distant targets

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2
Q

What is neurocrine?

A

signal from a neuron down its axon via blood to distant target

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3
Q

All Hormones only produced by their respective glands?

A

Nope, multiple endocrine glands can make same hormones

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4
Q

each hormone only has a single target?

A

Nope, multiple target and function

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5
Q

purpose of autocrine and paracrine?

A

extracellular messages

local communication

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6
Q

Lipophilic is also?

A

Hydrophobic

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7
Q

Hydrophilic also equals

A

lipophobic

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8
Q

why is permeability and solubility important?

A

in terms of location of receptors

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9
Q

Neurotransmitters use for transmitting what kind of message?

A

rapid, localised, specific, smaller distance

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10
Q

Neurohormones are secreted by? into?

A

by neuron

into blood stream

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11
Q

3 examples of neurohormones

A
  1. hypothalamus to ant. pit and 2. post. pit

3. catecholamines

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12
Q

catecholamines made where? by what?

A

made by neurons

modified adrenal medulla

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13
Q

What is a tropic hormone?

A

a hormone that controls secretion of another hormone

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14
Q

Two big hormone receptor types?

A

GPCR

Tyrosine Kinase-linked receptors

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15
Q

Peptide hormones release is how? solubility?

A

exocytosis, hydrophilic

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16
Q

Peptide hormones half life?

A

short

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17
Q

Peptide hormones receptor location?

A

cell membrane

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18
Q

2 examples of Peptide hormones?

A

insulin

parathyroid

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19
Q

Steroid hormones release and solubility?

A

simple diffusion

lipophilic

20
Q

Steroid hormones synthesis/storage?

A

made on demand from cholesterol

21
Q

peptide hormones synthesis and storage?

A

made in advanced and stored in secretory vesicles

22
Q

Steroid hormones location of receptor

A

cytoplasm or nucleus

23
Q

eg. of Steroid hormones?

A

androgens
estrogen
cortisol

24
catecholamines synthesis and storage?
made in advance and stored
25
catecholamines release and solubility?
exocytoic | hydrophilcic
26
catecholamines half life?
short
27
steroid hormones half life?
long
28
catecholamines receptor target?
cel membrane
29
catecholamines receptor response?
2nd messenger syetm
30
eg. of catecholamines? 2?
epinephrine | norepinephrine
31
Thyroid hormones half life?
long
32
Thyroid hormones release and solubility?
simple diffusion | lipophilic
33
peptide hormones in the ER are created as a?
Prohormone
34
The peptide hormone is active or inactive in the storage vesicles?
active
35
what is a precursor molecule to catecholamines and thyroid hormones?
Tyrosine
36
What two kind of hormones generate 2nd messengers?
peptide | catecholamines
37
Thyroid hormones travel how through blood stream?
bound to TBG
38
how are steroid hormones removed?
conjugation > urination
39
Amine hormones are removed how?
specific degrading enzymes
40
how are large peptide hormones removed?
receptor-mediated endocytosis
41
how are smaller peptide hormones removed?
kidneys
42
Positive feedback loop example?
labour and LH surge
43
2 ways to regulate hormone secretion
1. neuroendocrine reflexes | 2. feedback
44
Pineal gland makes?
Melatonin
45
What is permissive hormone regulation?
first hormone can't affect without presence of second hormone
46
eg. of hormone antagonism?
insulin | glucagon
47
2 ways to down regulate hormone secretion
1. endocytosis | 2. target cell desensitisation
48
primary vs. secondary endocrine disorder?
primary: gland itself secondary: excessive or abnormal stim