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Flashcards in Endocrine disorders Deck (20)
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1

What drugs lead to osteopenia

-Corticosteroids
-anticonvulsants
-HIV drugs
-Alcohol
-blood thinners

2

Corticosteroid effects on bone (2) and endogenous source

-Osteoperosis
-Osteonecrosis (AVN)

Endogenous source- Cushings syndrome

3

Cushing syndrome: age, m/f, mc Cause

20-50 yoa
women>m
-Pituitary adenoma (ACTH secreting tumor)

4

Cushing syndrome si/s (4)

-rapid weight gain
-moon face
-thin skin, purple striae
-mental issues

5

Cushings syndrome major complications

skin inf
diabetes
hypertension
avn * (HAVE TO RULE THIS OUT W THESE PTS)

6

What is kummels disorder and what is it associated w

Gas containing compression fx

-due to corticosteroid induced avn

7

What are the 3 major forms of Hyperparathyroidism

Primary- increased PTH from gland itself

Secondary- renal disease (leading to calc loss)

Tertiary- latrogenic due to dialisis

8

What are the key imaging findings in hyperparathyroidism (4+1)

-Osteopenia
-Subperiosteal bone resorption
-subchondral resporption
-brown tumours
(rugger jersey spine)

9

What are the soft tissue findings of HPTH

renal calculi
Vascular calcifications

10

Where is subperiosteal bone resoption found

m/c in hands (radial surface)

11

Brown tumor characteristics

painless eccentric lytic lesion

12

Subchondral resporption common locations (3)

Distal clavicles
SI jt
Symphysis pubis

13

subligamentous resoption mc locations (3)

Trochanters
vert bodies
calcaneous (inf)

14

What is acromegaly and mc cause

overprod of GH
MC cause pituitary adenoma

15

Difference bw acromegaly + gigantism

Acromegaly- post skeletal maturity

Gigantisim- prior to skeletal maturity

16

Acromegaly complications (4)

Arthritis
type 2 diabetes
hypertension
heart disease

17

Imaging findings of acromegaly(4)

-Enlarged sella turica
-Jt spaces initially appear wide
-spade like tufts
-widening of tubular bones

18

What heal pad thicness is associated w acromegaly

>20mm

19

What are key aspects to look for in diabetes

ulcers/sinus tracts
air lucencys
lytic destruction

20

What is a major complication in diabetic foot

osteomyelitis/ Septic arthritus (s aureus)