Endocrine Part 1 Flashcards

(44 cards)

1
Q

What does thyroid produce??

A

T3, T4, Calcitonin

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2
Q

How does calcitonin work?

A

Decreases serum calcium by taking it from the blood and putting it back in the bone

Tx osteoporosis

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3
Q

What do you need to make hormones?

A

Dietary Iodine

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4
Q

What hormone gives us energy?

A

Thyroid hormone

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5
Q

S/S Hyperthyroidthyroidism (Graves)

Energy?
Wt: 
Temp: 
Attention: 
Constipation or diarrhea?
BP:
A
TOO MUCH energy
Wt: Loss
Temp: Hot/sweaty
Attention span decreases (can't focus)
Nervousness / irritable
GI: fast - Diarrhea
BP ^
Thyroid enlarges/hypertrophy
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6
Q

How do we diagnose hyperthyroidism?

A
T4 count (Increased)
Thyroid scan
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7
Q

What must a patient do before obtaining a thyroid scan?

A

DC any iodine containing medication 1 week prior to the scan

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8
Q

What drug contains high levels of iodine?

A

Amiodarone - may affect thyroid function

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9
Q

5 ways to treat hyperthyroidism

A
  1. Anti-thyroids
  2. Iodine compounds
  3. Beta blockers
  4. Radioactive Iodine
  5. Surgery
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10
Q

What are 2 examples of anti-thyroid medications?
How do they work?
When is it used?

A

propylthiouracil, methimazole

Stops the thyroid from making hormones

Used preoperatively to stun the thyroid (decrease bleeding risk)

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11
Q

2 examples of iodine compounds
Are these the same as dietary iodine?
How does it work?
How do we give it?

A

Potassium iodine, strong iodine solution (Lugol’s)
NO
These decreases the size and vascularity go the gland - all endocrine glands are VERY VASCULAR

Give in milk or juice and use a star because it stains teeth

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12
Q

How to BB work in regards to hyperthyroidism?

Who do we not give these to?

A

Decrease HR, BP, contractility, CO generally, but especially decrease anxiety in these patients

Asthma, DM (masks glucose changes)

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13
Q

How does radioactive iodine work? What does this lead to? Is this adverse?

A

Destroys the thyroid cells
Hypothyroidism
This is expected, not adverse

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14
Q

How many doses of radioactive iodine are given?

How are they given?

A

1

PO (liquid or tablet) after pregnancy is ruled out

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15
Q

Precautions to taking radioactive iodine

A

Stay away from babies and no kissing for 24 hours

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16
Q

What is a thyroid storm?

A

Also called thyrotoxicosis and thyrotoxic crisis, it is like hyperthyroidism x 100

Could be a rebound effect after radioactive iodine (But can occur without it)

EMERGENCY - ICU: could lead to MI

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17
Q

Post-op teaching of thyroidectomy (total or partial)

A

Support the neck to avoid any tension on the suture line

Put personal items close by

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18
Q

How do we position a patient after a thyroidectomy?

Where do we check for bleeding?

A

Elevate HOB to prevent edema in the neck

Check for bleeding behind the neck

19
Q

Nutrition after thyroid removal

A

Increased calories because they are burning do many

20
Q

What would hoarseness indicate after thyroid removal?

What could this lead to?

A

Damage of the laryngeal nerve

Vocal cord paralysis or airway obstruction & immediate trach if both cords have paralysis

21
Q

Do we want thyroidectomy patients to speak much?

A

No, but we need to listen for hoarseness and teach them to report ANY feelings of pressure

ASSUME THE WORST

22
Q

Why do we keep a trach at the bedside?

A

Swelling
Laryngeal nerve damage
Hypocalcemia

23
Q

What could have been removed when removing the thyroid?

How would we know?

A

Some of the parathyroid glands (there are 4 total)

Assess for LOW CALCIUM - *not enough sedation (think about laryngospasm especially here)

24
Q

What is not fixed when removing the thyroid?

What do we do about it?

A

Eye or vision problems

Hypoallergenic tape if they can’t close their lids
Dark glasses for photosensitivity
Artificial tears

25
Another name for hypothyroidism | What is this called when it is present at birth?
Myxedema | Cretinism - can lead to slowed mental status and physical development if undetected
26
S/S hypothyroidism ``` Energy? GI Weight Temp - precautions? Women Speech Face ```
``` No energy - Could be so bad they are BEDRIDDEN Slow GI Increased weight Amenorrhea Slowed/slurred speech No expression ``` Cold - can't tell if something is too hot.. don't give them things like heating pads
27
Hypothyroid and Hyperthyroid could be mistaken for what?
Depressed or Manic Psych - Need a thyroid profile
28
Medication for hypothyroidism How often taken? What effect will they have on the patient?
Levothyroxine, thyroglobulin, liothyronine Once a day for life Increased energy, BP, HR
29
Common comorbidity with hypothyroidism
CAD - worry about heart trouble and chest pain!
30
Too much PTH will cause _____ while too little PTH will cause _____
Too much PTH = ^ serum Ca | Too little PTH = low serum Ca
31
Hyperparathyroidism = what 2 things
Increased calcium - sedated | Low Phosphorus
32
HypOparathyroidism = what 2 things
Low Ca - rigid | Increased Phosphorus
33
How to treat Hypoparathyroidism
IV calcium to increase Ca | Phosphate binders to lower phosphorus
34
What do adrenal glands help us do?
Deal with stress
35
What does adrenal medulla have vs adrenal cortex? | Problems associated with each?
Medulla: Epi and NE; pheochromocytoma Cortex: Glucocorticoids, Mineralocorticoids, Sex hormones; Addisons, Cushings
36
What is Pheochromocytoma
Benign tumors that secrete epi and NE in boluses
37
S/S pheochromocytoma
^BP, ^HR | Flushing/sweaty
38
How do you diagnose pheochromocytoma? How is it done? What are we looking for? What will alter results?
VMA (vanillylmandelic acid test) 24 urine - throw away the first void and keep the last - can't miss a single mL or else start over Look for epi and NE No stress the day before to prevent any boluses VANILLA WILL ALTER THIS
39
How to treat pheochromocytoma?
Surgery to remove tumors
40
PO/IV vs biologic GC, MC and sex hormones?
Even though our body secretes these normally, adverse effects are more pronounced when the patient receives PO/IV steroids
41
What are the 4 functions of glucocorticoids?
1. Change mood 2. Alter defense mechanisms (Suppress immune system) 3. Breakdown fats and proteins (alter growth) 4. Inhibit insulin (hyperglycemic)
42
What does aldosterone do to the body?
Makes you retain Na and water and LOSE K
43
Too much aldosterone = ___ K | Too little aldosterone = ___ K
Too much: low K, fluid excess | Too little: high K, fluid deficit
44
Other "fancy words" NCLEX lady will use for increased steroids
Adrenocorticotropin (ACTH) Cortisol Hypercortisolism