Endocrine Physiology ML:4

Question 1

What is the functional unit of the thyroid gland?

Answer 1

follicles

Question 2

How are thyroid hormones stored?

Answer 2

They are really hydrophobic so they can be bound to thyroglobulin which is a protein that is stored in the colloid

Question 3

True or False: The thyriod hormone is stored in the colloid fluid until it is stimulated to be secreted

Answer 3

true

Question 4

How are thyroid hormones transferred to the blood?

Answer 4

by protein carriers

Question 5

TBG protein carrier

Answer 5

70%

Question 6

TTR protein carrier

Answer 6

10-15%

Question 7

Albumin protein carrier

Answer 7

15-20%

Question 8

What kind of hormone is a thyroid hormone

Answer 8

hydrophobic amine hormone
-binds to receptors inside the target cell

Question 9

Characteristics of T4

Answer 9

90% of secretion
“storage pool” in blood
converted to T3 inside target cells

Question 10

Characteristics of T3

Answer 10

most active form (bound to receptors in target cells)

Question 11

Three gland cascade: thyroid gland

Answer 11

-hypothalamus secretes TRH
-anterior pituitary secretes TSH
Thyroid gland secretes T3 and T4

Question 12

What are the three actions of the thyroid hormone?

Answer 12

metabolic
permissive
growth and development

Question 13

Metabolic actions

Answer 13

controls BMR and body temp mainly by increasing sodium and potassium

Question 14

Permissive actions

Answer 14

increases catecholamine expression

Question 15

Growth and development

Answer 15

TH is needed for normal production of growth hormone (GH) and essential for fetal CNS development and function and adult nervous system function

Question 16

Follicles trap what in order to produce thyroid hormones

Answer 16

iodine