Mini Lesson Flashcards

1
Q

Osteoblast

A

coverts cartilage to bone

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2
Q

Bone Growth Order (top-down)

A

-top of epiphyseal growth plate
-Epiphyseal growth plate
–just above the shaft you have cells undergo hypertrophy
-above that you have cells undergoing hyperplasia which is cell division
-shaft containing osteoblasts

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3
Q

Environmental factors that influence growth

A

adequate nutriton
freedom from chronic illness/disease
freedome from chronic stress
sleep

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4
Q

Testerone during puberty

A

stimulates GH and IGF-1 secretions prolonged exposure stimulates GH and IGF-1 secretions

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5
Q

Cortisol

A

exerts antigorwth effects such at catabolism, decalificaion of bone, inhibits GH and IGF-1 secretion

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6
Q

High GH and low cortisol

A

growth

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7
Q

HIGH GH and HIGH CORTSIOL

A

fuel mobilization, no growth

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8
Q

What is the most common cause of excess growth hormone

A

hypersecreting tumor of AP

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9
Q

Acromegaly

A

too much GH after epiphyseal plates close

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10
Q

Gigantism

A

too much GH before epiphyseal plates close

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11
Q

GH stimulates growth by

A

stimulating cell differentiation and dividison
-stimulation of protein synthesis
stimulating IGF-1

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12
Q

GH metabolic effects include

A

mobilize glucose for energy
mobilize fatty acids for energy

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13
Q

IGF-1 promotes growth by

A

stimulating cell division and protein synthesis

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