endocrine system Flashcards

(32 cards)

1
Q

what is another term for the pituitary gland

A

hypophysis

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2
Q

how are endocrine glands different than exocrine

A

they are ductless and release hormones into interstitial tissue then pass to the blood are lymphatic circulation

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3
Q

what is the function of the pituitary gland ( hypophysis)

A
  • produces hormones to regulate growth, reproduction, and metabolism
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4
Q

what are the 2 branches of the pituitary gland

A

adenohypohphysis ( anterior pituitary)
and neurohypopysis (posterior pituitary)

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5
Q

What is the adenohypophysis made up of and what are the three subdivisions?

A
  • made of glandular epithelium
  • anterior lobe ( pars distalis)
  • intermidiate lobe ( pars intermedia):
  • largest lobe (pars tubularis): thin layer of CT surroounding the infundibular stalk
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6
Q

what is the neurohypophysis made up of and what are the 3 subdivisions?

A
  • made up of neural tissue
  • median eminenece: connects the the gland to the hyopthalmus
  • infundibular stalk ( where the hypothalamic-hypophyseal tract runs)
  • pars nervosa
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7
Q

what is the neurohypophysis a direct extention of?
what does it do ?

A

neurohypophysis is a direct neuronal extention of the hypothalmus and it stores and releases hormones made by the hypothalmus

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8
Q

which are the hormones made by the hypo thalmus that the neurohypophysis secretes, via which layer?

how do they get the the neurohypohysis

A

pars nervosa - secretes oxytcoin and ADH ( vasopressin)
- they get transported to the neurohypopysis ( posterior pituotary) hypothalmic-hypophyseal tract made of unmyleinated axons

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9
Q

what are herring bodies

A
  • unique feature of the neurohypophysis and they contain aggregates of neurosecretory mateiral which are stored before release
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10
Q

how is the adenohypophysis different than the neurohypopysis?
what hormones are secreted by the adenohypophysis ( anterior pituitary)

A
  • it produces its own hormones in response to hypothalmic releasing hormones
  • FSH - follicle stimulating hormone
  • LH - lutinizing hormone
  • ACTH - adrenocorticotropic hormon)
  • TSH ( thyroid stimulating hormone)
  • GH - growth hormone
    -prolactin
  • basophils
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11
Q

what hormones do basophils release

A

FSH
LH
ACTH
TSH

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12
Q

what hormones do acidophils release

A

-prolactin
- endorphins
- GH

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13
Q

what are the hypothalmic releasing hormones that trigger the release of hormones from the anterior pituitary

A
  • GnRH - gonadotropin releasing hormone > stimulates the release of FSH and LH
  • TRH - thyrotropin releasing hormone» stimulates the relase of TSH
  • CRH - corticotropin releasing hormone> stimulates the release of ACTH
  • GRH- growth hormone releaseaing hormone&raquo_space; stimulates the release of GH
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14
Q

where is the adrenal gland located and what are the two subdivisions

A
  • located on the superior pole of the kindey
  • cortex and medulla
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15
Q

what is the function of the adrenal glands

A

regulates the stress response

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16
Q

what is the adrenal cortex stimulated by

A
  • stimulated by ACTH ( adrenocorticotropic hormone) released by the anterior pituitary and angiotensin 2 ( kidney)
17
Q

what types of hormones are released by the adrenal cortex and what are they?

A
  • releases gluccocorticoids ( cortisol): increases Blood glucos during long term stress
  • releases mineralcoticoids ( aldosterone): increases blood volume
  • androgens : male sex hormone
18
Q

what does ACTH and angiotensin 2 stimulate the release of

A

ACTH - gluccorticoids
angitoensin 2 - mineralcorticoids and androgens

19
Q

what is the adrenal medulla stimulated by
what type of stress does it deal with

A

the sympathetic ANS
- short term stress

20
Q

what types of hormones are realseased by the adrenal medulla and what are they

A
  • amino acid derived - catecholamines
  • epeinepherine / adrenaline and norepinephrine/ noradrenaline
21
Q

what are the layers of the adrenal cortex and what do

A

zona glomerulosa - mineralcorticoids ( aldosterone)
zona fasciuculata - gluccocorticoids (cortisol)
Zona reticularis - weak androgens

22
Q

what reaction do mineralcorticods ( aldosterone) cause

A
  • causes a reaction at the distal convoluted tubule in the kidney where it prompts the reabsorption of sodium.
23
Q

what do gluccocorticoids (cortisol) cause the inhibition of
THIS IS DEF A QUESTION

A

the immune response

24
Q

-How do hormones from the hypothalmus transported to the pars nervosa in the neurohpopysis
- what triggers the secretion of oxytocin and ADH/vasopressin from the pars nervosa

A
  • they are transported from the hypothalmaus via the hypothalamic - hypophysisal tract to the pars nervosa where they wait for an action potential to trigger their secretion
25
hypophyseal portal system - what are the components and functions
links the hypothalamus to the pars distalis There are 2 capillary networks: - the first capillary network form in the hypothalamus - the second capillary network in the pars distalis - a vein connects the 2 capillaries - this allows the hypothalmic releasing hormones to travel to the pars distalis and to trigger the release of the hormones produced there
26
what is the difference between the hypophyseal portal system and the hypothalamic - hypophyseal tract
- the portal system allows for the hypothalamus to trigger the release of hormones produced by the adenohypysis by hypothalamic releasing hormone - the hypothalamic - hypophyseal tract allows the hormones produced by the hypothalamus to travel and be stored from the neurohypopysis.
27
what is responsible for calcium homeostasis in the blood
- parathyroid hormone - released when Ca is low they trigger osteoclasts that resorb bone and release Ca - calcitonin - produced by the thyroid gland and released by the parafolicular cells to decrease Ca via osteoblasts to form bone
28
what are the median eminence and adrenal medulla derived from
neural tube???????
29
- which cells of the endocrine system are of neural origin - which have mesodermal origin?
-thyroid parafollicular cells, adrenal medula, pars nervosa, infundibular stalk, median eminence, pituitary, pineal gland - adrenal cortex = mesoderm
30
what is a thyroglossal duct cyst and what tissue is it made up of and what is lined with
- occurs when the thyrodlossal duct does not degenerate and is made of thyroid tissue - lined with respiratory epithelium
31
what is the pathway for increasing blood ca
- PTH binds osteoblasts - increases RANKL expression - RANKL binds RANK on osteoclast precursor - Precursor is activated = osteoclast - osteoclasts resorb bone
32
what is the pathway for decreasing blood ca
- calcitonin inhibits osteoclasts - osteogenic cells become osteoblasts - they form bone and decrease ca