Endocrine system Flashcards

(32 cards)

1
Q

major endocrine glands

A

hypothalamus
thyroid
parathyroid
pineal
islets of langerhans
adrenals
pituitary

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2
Q

what does t

A
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3
Q
A
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4
Q

what does the thyroid gland secrete?

A

T3, T4, and calcitonin

T3, and T4 increase metabolism and increase growth development

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5
Q

what do the adrenal glands secrete?

A

epinephrine and norepinephrine

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6
Q

pancreas secretes…

A

insulin and glucagon

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7
Q

pituitary gland

A

the master endocrine gland

makes growth hormone
TSH thyroid stimulating hormone

prolactin

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7
Q

5 diff types of cells in anterior pituitary

A

Somatotropes –> GH

lactotropes or mammotroph?–> PRL

gonadotropes –> FSH and LH

corticotropes –> ACTH

thyrotropes –> TSH

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8
Q

Graves disease

A

Body creates antibodies to the TSH receptors on follicular cells

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9
Q

parathyroid

A

secretes parathormone –> secreted in response to low concentrations of calcium, if this doesnt work then the thyroid will secrete calcitonin

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10
Q

adrenal gland

A
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11
Q

what are the layers to the adrenal gland regions?

A

Adrenal cortex and

adrenal medulla –> stress hormone
stimulate sympathetic ANS (epinephrine and norepinephrine)

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12
Q

what are the adrenal cortex zones?

A

Zona reticularis –> stimulat emasculinizationsandrogens

zona fascuculata –> Glucocorticosteroids - Regulate glucose metabolism (Cortisol, corticosterone, cortisone)

zona glomerulosa –> regulate mineral balance (mineralcorticoids) (ALDOSTERONE)

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13
Q

cushing syndrome

A

elevated circulating corticosteroid, especially cortisol

effects mroe women than men

caused by ACTH-secreting pituitary adenomas, which lead to pituitary and adrenal histopathology

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14
Q

addisons disease

A

primary adrenocortical insufficeincy
disorder of the adrenal cortex leading to inadequate production of glucocorticoid and mineralocorticoid hormones.

causes:
incomplete development of the cortex or its destruction by autoimmune disease ,
Severe infection such as tuberculosis , or idiopathic atrophy .

Insufficient corticosteroid hormones result in raised pituitary ACTH levels

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15
Q

tumors of the adrenal gland

A

Pheochromocytoma and neuroblastoma

neuroblastoma is a malignant tumor of infant and childhood

16
Q

kidneys are retroperitoneal

17
Q

Pancreas cell types and hormones

A

major exocrine gland of the digestive tract

Alpha cells - Glucagon

Beta Cells - INSULIN

Delta cells - SOMATOSTATIN

18
Q

major componenet of homeostatic response of hypothalamic pituitary adrenal axis

A

mediates the effects of stressors by regulating metabolism, immune response, and the ANS

19
Q

circulating hormones

A

Hormones that travel in blood and act on distant target cells are called circulating hormones or endocrines.

20
Q

Local hormones

A

Hormones that act locally without first entering the blood stream are called local hormones.

21
Q

Types of intercellular communication

A

Autocrine –> a cell targets itself

Paracrine –> a cell signals a nearby cell

Endocrine –> a cell targets a distant cell through the bloodstream

22
Q

both endocrine and nervous system s

A

share many chemical messengers ( norepinephrine and epinephrine)

are regulated mainly by negative feeback

23
Q

RAAS –> renin-angiotensin-Aldosterone system

A

regulates blood pressure, fluid and electrolyte balance, and systemic vascular resistance

converts prorenin to renin

renin converts angiotensin to angiotensin I by angiotensinogen

Angiotensin I converts to angiotensin II by the converting enzyme angiotensin converting enzyme (ACE)

Angiotensin II gets degraded to angiotensin III

24
Angiotensin inhibitors
ACE inhibitors prevents enzyme in the body from making angiotensin II (which is a substance that narrows the blood vessels) helps relax the veins and arteries to lower blood pressure
25
RAAS INcreaseing
Increase inflammation, causes an increased in your RAAS system and an increase in your angiotensin II
26
nephron in kidneys, two main parts
Tubules --> has three parts , two highly coiled parts, loop of henle, and distal convoluted tubule corpuscles
27
loop of henle
is ALWAYS a U shaped tubule, with a descending limb and an ascending limb
28
juxtaglomerular apparatus (JGA)
Regulates filtration granular cells --> enlarged
29
baroreceptorsplasma osmolality
Plasma osmolarity increases --> ADH releases --> water gets reabsorbed --> decreases plasma osmolarity --> ADH stops releasing
30
LIVER
produces CO2, WATER and LACTATE is responsible for, glycogen, production of glucose, glycogenolysis, glucose goes to your muscle
31
know what the organ is and what hormones