Endocrineywiney Flashcards Preview

6 Endocrine > Endocrineywiney > Flashcards

Flashcards in Endocrineywiney Deck (37)
Loading flashcards...
1

What HRT should be given to ladies without a uterous

don't need progesterone- only women with uterus need

2

why is HRT used in early menopause

because women are at increased risk of oesteoperosis

3

Why are we giving progesterone cyclically with the oestrogen

to prevent cancer of the uterous (or the missing but in a hyderectomy) from developping

4

Is tibolone given cyclically

no - continuous

5

when is early menopause and how long do we treat it for

before 45

treat until usualy menopause - 50

6

under what age do the benifits of HRT probably outweigh the risks

under 60

7

how many days of the cycle is progesterone given

at least 10 of 28

8

when is the risk of DVT with HRT highest

first year

9

how long before surgery should we stop hrt

4-6 weeks

10

What are the rules for when pred should NOT be abruptly withdrawn

- dose over 40mg for over 1 week
- repeated doses in the evening
- more than 3 weeks treatment
- short course within 1 year of stopping long term therapy
- received repeated short courses (particularly if taken for longer than 3 weeks)

11

why is hydrocortisone not suitable long term (use pred instead)

high mineralocorticoid activity resulting in fluid retention)

12

what vaccines should be avoided in people receiving systemic corticosteroids

live

13

diseases someone on long term steroids should be councelled about

avoid chicken pox, measales, shingles

14

what is the purpose of the dexamthasone suppression test

diagnose cushing syndrome

15

5 mineralocorticoid side-effects

hypertension
sodium retension
water retention
potassium loss
calclium loss

16

what suprise drug is used to TREAT cushing syndrome

What is the caution with this

ketoconazole

liver toxicity- no longer recommended for antifungal effect

17

when is BM monitoring suitable in T2DM

insulin treated
using drugs causing hypos
to monitor effects of lifestyle changes or illness
to ensure safe levels when driving

18

how much glucose is used to treat a hypo initially....
and then

10-20g
repeat if needed after 10-15 mins

then have a long acting carb snack

19

what is used to treat an unconcious hypo

glucagon - when possible carbs by mouth

20

what % glucose is idea for treating hypo by IV

20%

50% increased risk of extravisation

21

what is an option for treating post menopausal arthritis if bisphosphoantes are not an option
(3)

HRT - but bone loss continues once stopped

calcitrol
strontium

22

why is calcitonin salmon no longer recommended for oesteoperosis?

risk of malignancy outweighs benifits

23

when in steroid therapy does the most bone loss occur

first 6-12 months

24

consider prophylaxic treament for oesteoperotic fractures for people likely to be taking steroids for how long

over 3 months

25

strotium ranelate has what warning associated with it

CV risk

26

what oesteoperosis fracture preventing drug must be stopped for temporary or prolonged immobilisation

strontium

27

Which is longer acting desmopressin or vasopressin?

Which is used for maintinance of diabetes insipudus

Desmonpressin - longer acting maintaince

28

which has vasocontrictor effect, desmopressin or vasopressin?

Vasopressin - so used for variceal bleeding in portal hypertension

29

what drug is used to correct hyponautremia caused by inapprpriate secretion of antidiuretic hormone

demeclocycline

30

electrolyte imbalance caused by demopressin

hyponautraemic convulsion