Endocrinology Flashcards

(62 cards)

1
Q

Cortisol is an example f what pattern

a. Cyclicity
b. Pulsatility
c. Feedback mechanism

A

Cortisol is an example f what pattern

a. Cyclicity
b. Pulsatility
c. Feedback mechanism

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2
Q

An increased in the product also increases the activity of the system and the production rate (gonadal, thyroidal and adenocortical hormones).

A

POSITIVE Feedback System

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3
Q

An increased in the product decreases the activity of the system and the production.

A

NEGATIVE Feedback System

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4
Q

Hormones with regulatory function.

a. Vasopresin and Aldosterone
b. Testosterone and Estradiol 17 B
c. Insulin

A

Hormones with regulatory function.

a. Vasopresin and Aldosterone
b. Testosterone and Estradiol 17 B
c. Insulin

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5
Q

Hormones with morphogenesis function.

a. Vasopresin and Aldosterone
b. Testosterone and Estradiol 17 B
c. Insulin

A

Hormones with morphogenesis function.

a. Vasopresin and Aldosterone
b. Testosterone and Estradiol 17 B
c. Insulin

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6
Q
  • Classic hormones
  • Secreted into the blood stream & reach target organs which are distant from the source

a. Endocrine
b. Paracrine
c. Autocrine
d. Neurocrine

A
  • Classic hormones
  • Secreted into the blood stream & reach target organs which are distant from the source

    a. Endocrine
    b. Paracrine
    c. Autocrine
    d. Neurocrine
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7
Q
  • Reach their target within the same site by diffusing through the interstitial fluid
  • Cytokines

a. Endocrine
b. Paracrine
c. Autocrine
d. Neurocrine

A
  • Reach their target within the same site by diffusing through the interstitial fluid
  • Cytokines

    a. Endocrine
    b. Paracrine
    c. Autocrine
    d. Neurocrine
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8
Q
  • Hormones act back on the cells which act as the source of the hormones to modulate their secretion or intracellular processes involved
  • Prolactin

a. Endocrine
b. Paracrine
c. Autocrine
d. Neurocrine

A
  • Hormones act back on the cells which act as the source of the hormones to modulate their secretion or intracellular processes involved
  • Prolactin

a. Endocrine
b. Paracrine
c. Autocrine
d. Neurocrine

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9
Q
  • Neurohormones
  • Acetylcholine
  • Dopamine
  • Oxytocin

a. Endocrine
b. Paracrine
c. Autocrine
d. Neurocrine

A
  • Neurohormones
  • Acetylcholine
  • Dopamine
  • Oxytocin

a. Endocrine
b. Paracrine
c. Autocrine
d. Neurocrine

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10
Q
  • Cortisol
  • Aldosterone
  • Estrogen
  • Progesterone
  • Testosterone
  • Vitamin D

a. Proteins
b. Glycoproteins
c. Steroids
d. AMino acid derivative

A
  • Cortisol
  • Aldosterone
  • Estrogen
  • Progesterone
  • Testosterone
  • Vitamin D

    a. Proteins
    b. Glycoproteins
    c. Steroids
    d. AMino acid derivative
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11
Q

composed of chains of amino acids only which may number <100

a. Amines
b. Polypeptides
c. Steroids
d. Glycoprotein

A

composed of chains of amino acids only which may number <100

a. Amines
b. Polypeptides
c. Steroids
d. Glycoprotein

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12
Q

FSH, LH, TSH, hcG are examples of

a. Amines
b. Polypeptides
c. Steroids
d. Glycoprotein

A

FSH, LH, TSH, hcG are examples of

a. Amines
b. Polypeptides
c. Steroids
d. Glycoprotein

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13
Q
  • Derived from cholesterol thru some multi-enzyme processes
  • Separated based on the # of C atoms

a. Amines
b. Polypeptides
c. Steroids
d. Glycoprotein

A
  • Derived from cholesterol thru some multi-enzyme processes
  • Separated based on the # of C atoms

a. Amines
b. Polypeptides
c. Steroids
d. Glycoprotein

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14
Q

Estrogens, Androgens, Glucocorticoids are examples of

a. Amines
b. Polypeptides
c. Steroids
d. Glycoprotein

A

Estrogens, Androgens, Glucocorticoids are examples of

a. Amines
b. Polypeptides
c. Steroids
d. Glycoprotein

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15
Q

these 20-carbon molecules are derived from the fatty acid, arachidonic acid

a. Amines
b. Polypeptides
c. Steroids
d. Eicosanoids

A

a. Amines
b. Polypeptides
c. Steroids
d. Eicosanoids

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16
Q

Prostaglandins, prostacyclin, leukotrienes, thromboxanes

a. Amines
b. Polypeptides
c. Steroids
d. Eicosanoids

A

Prostaglandins, prostacyclin, leukotrienes, thromboxanes

a. Amines
b. Polypeptides
c. Steroids
d. Eicosanoids

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17
Q

Hormones that stimulate the growth and activity of other endocrine glands

a. Releasing
b. Inhibiting
c. Trophic
d. Effector

A

Hormones that stimulate the growth and activity of other endocrine glands

a. Releasing
b. Inhibiting
c. Trophic
d. Effector

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18
Q

These are secreted by all endocrine glands responsible for causing changes in physiologic processes.

a. Releasing
b. Inhibiting
c. Trophic
d. Effector

A

These are secreted by all endocrine glands responsible for causing changes in physiologic processes.

a. Releasing
b. Inhibiting
c. Trophic
d. Effector

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19
Q

biocheimical property that is
- lipophilic
- administered orally as a drug
- has long plasma half-life
-* steroids, thyroid hormones, calcitriol, retinoids*

a. Group I
b. Group II

A

biocheimical property that is
- lipophilic
- administered orally as a drug
- has long plasma half-life
- steroids, thyroid hormones, calcitriol, retinoids

**a. Group I **
b. Group I

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20
Q

Biocheimical property that is

  • Hydrophilic
  • Administered IV as a drug
  • No transport protein needed
  • Short plasma half – life
  • Receptor location is plasma membrane; cAMP, cGMP, Ca++
  • Takes longer to initiate a reaction but is sustained for a prolonged period
    - Catecholamines, polypeptides

a. Group I
b. Group II

A

Biocheimical property that is

  • Hydrophilic
  • Administered IV as a drug
  • No transport protein needed
  • Short plasma half – life
  • Receptor location is plasma membrane; cAMP, cGMP, Ca++
  • Takes longer to initiate a reaction but is sustained for a prolonged period
    - Catecholamines, polypeptides

a. Group I
b. Group II

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21
Q
A
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22
Q

The majority of endocrine functions are regulated through the ____ gland, which in turn is controlled by secretions from the hypothalamus.

A

pituitary gland

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23
Q
  • small organ located below the brain, above the pituitary gland
  • connected to posterior pituitary gland through INFUNDIBULAR STALK
A

hypothalamus

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24
Q

stimulated the release of ACTH and other hormones

a. Corticotropin-releasing hormone (CRH)
b. Thyrotropin-releasing hormone (TRH)
c. Gonadotropin-releasing hormone (GnRH)
d. Prolactin-releasing factor (PRF)

A

stimulated the release of ACTH and other hormones

a. Corticotropin-releasing hormone (CRH)
b. Thyrotropin-releasing hormone (TRH)
c. Gonadotropin-releasing hormone (GnRH)
d. Prolactin-releasing factor (PRF)

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25
stimulates the release of FSH and LH a. Corticotropin-releasing hormone (CRH) b. Thyrotropin-releasing hormone (TRH) c. Gonadotropin-releasing hormone (GnRH) d. Prolactin-releasing factor (PRF)
stimulates the release of FSH and LH a. Corticotropin-releasing hormone (CRH) b. Thyrotropin-releasing hormone (TRH) **c. Gonadotropin-releasing hormone (GnRH)** d. Prolactin-releasing factor (PRF)
26
It is also known as somatocrinin. a. Corticotropin-releasing hormone (CRH) b. Thyrotropin-releasing hormone (TRH) c. Growth hormone-releasing hormone (GHRH) d. Growth hormone-inhibiting hormone-
It is also known as somatocrinin. ​ a. Corticotropin-releasing hormone (CRH) b. Thyrotropin-releasing hormone (TRH) **c. Growth hormone-releasing hormone (GHRH)** d. Growth hormone-inhibiting hormone-
27
It is also known as somatostatin. ​ a. Corticotropin-releasing hormone (CRH) b. Thyrotropin-releasing hormone (TRH) c. Growth hormone-releasing hormone (GHRH) d. Growth hormone-inhibiting hormone-
It is also known as somatostatin. * a. Corticotropin-releasing hormone (CRH) b. Thyrotropin-releasing hormone (TRH) c. Growth hormone-releasing hormone (GHRH) **d. Growth hormone-inhibiting hormone-**
28
- Aka the “MASTER GLAND” - Also referred to as “hypophysis”- undergrowth a. Hypothalamus b. Pituitary
- Aka the “MASTER GLAND” - Also referred to as “hypophysis”- undergrowth ​ **a. Hypothalamus** b. Pituitary
29
PG is located in a small cavity in the sphenoid bone of the skull called the
SELLA TURCICA
30
Responsible for the storage and release of Oxytocin and Vasopressin (ADH) a. Anterior/Adenohypophysis b. Posterior/Neurohypophysis c. Intermediate lobe
Responsible for the storage and release of Oxytocin and Vasopressin (ADH) a. Anterior/Adenohypophysis **b. Posterior/Neurohypophysis** c. Intermediate lobe
31
Poorly developed and has little functional capacity a. Anterior/Adenohypophysis b. Posterior/Neurohypophysis c. Intermediate lobe
Poorly developed and has little functional capacity a. Anterior/Adenohypophysis b. Posterior/Neurohypophysis **c. Intermediate lobe**
32
Secrete growth hormone a. Somatotropes b. Lactotropes c, Thyrotropes d. Corticotropes
Secrete growth hormone **a. Somatotropes** b. Lactotropes c, Thyrotropes d. Corticotropes
33
Secrete LH and FSH a. Somatotropes b. Lactotropes c, Gonadotropes d. Corticotropes
Secrete LH and FSH ​ a. Somatotropes b. Lactotropes **c, Gonadotropes** d. Corticotropes
34
Secrete ACTH a. Somatotropes b. Lactotropes c, Gonadotropes d. Corticotropes
Secrete ACTH ​ a. Somatotropes b. Lactotropes c, Gonadotropes **d. Corticotropes**
35
Secrete prolactin a. Somatotropes b. Mammotropes c, Gonadotropes d. Corticotropes
Secrete prolactin ​ a. Somatotropes **b. Mammotropes** c, Gonadotropes d. Corticotropes
36
Target of ACTH a. Adrenal gland b. All cells in the body c. Gonads d. Thyroid
Target of ACTH **a. Adrenal gland** b. All cells in the body c. Gonads d. Thyroid
37
Target of FSH a. Adrenal gland b. All cells in the body c. Gonads d. Thyroid
Target of FSH ​ a. Adrenal gland b. All cells in the body **c. Gonads** d. Thyroid
38
Target of Prolactin a. Adrenal gland b. All cells in the body c. Mammary gland d. Thyroid
Target of Prolactin a. Adrenal gland b. All cells in the body **c. Mammary gland** d. Thyroid
39
storage site of ADH and Oxytocin a. Adenohypophyssis b. Neurohypophysis
storage site of ADH and Oxytocin a. Adenohypophyssis **b. Neurohypophysis**
40
All of the following are direct effector hormones except a. Prolactin b. LH c. Growth Hormone
All of the following are direct effector hormones except a. Prolactin **b. LH** c. Growth Hormone
41
Most abundant of all pituitary hormones
GH
42
major growth factor induced by GH
IGF-1 (somatomedin C)
43
Excess GH developed in adulthood a. Gigantism b. Acromegaly
Excess GH developed in adulthood a. Gigantism **b. Acromegaly**
44
Gold standard for GH deficiency testing a. Insulin Tolerance Test b. Arginie Syimulation Test
Gold standard for GH deficiency testing **a. Insulin Tolerance Test** b. Arginie Syimulation Test
45
Confirmatory test for acromegaly a. Insulin Tolerance Test b. Arginie Syimulation Test c. Glucose Suppression Test
Confirmatory test for acromegaly a. Insulin Tolerance Test b. Arginie Syimulation Test **c. Glucose Suppression Test**
46
Hormone that is a chromophobe a. Thyrotropes b. Corticotropes c. Somatotropes
Hormone that is a chromophobe a. Thyrotropes **b. Corticotropes** c. Somatotropes
47
Hormone that stain blue a. Thyrotropes b. Corticotropes c. Somatotropes
Hormone that stain blue **a. Thyrotropes** b. Corticotropes c. Somatotropes
48
stress hormone
prolactin
49
49
inhibitory factor of prolactin
dopamine
50
consequence of prolactin excess
hypoganodism
51
in males hyperprolacteinemia results to
impotence
52
decreases production of urine by promoting reabsorption of water by renal tubules
ADH
53
deficient ADH, severe polyuria (>3L of urine), low specific gravity
Diabetes insipidus
54
deficiency of ADH with normal ADH receptor - failure of the pituitary gland to secrete ADH
True DI
55
- normal ADH but abnormal ADH receptor - renal resistance to ADH action
Nephrogenic Diabetes Insipidus
56
failure of the pituitary gland to secrete ADH a.True Diabetes Insipidus b. Nephrogenic Diabetes Insipidus
failure of the pituitary gland to secrete ADH **a.True Diabetes Insipidus** b. Nephrogenic Diabetes Insipidus
57
failure of the kidneys to respond to normal or elevated ADH levels a.True Diabetes Insipidus b. Nephrogenic Diabetes Insipidus
failure of the kidneys to respond to normal or elevated ADH levels a.True Diabetes Insipidus **b. Nephrogenic Diabetes Insipidus**
58
- occurs in cases of SIADH secretion - ADH is released despite low serum osmolality in association with normal or increased blood volume A. Relative B. Absolute
- occurs in cases of SIADH secretion - ADH is released despite low serum osmolality in association with normal or increased blood volume A. Relative **B. Absolute**
59
Laboratory test and specimen for ADH
RIA EDTA Plasma
60
- An indirect measure of ADH content - Water is withheld from the patient for 8 hours
Overnight water deprivation test
61
Serum osmolality in ADH ref range a. 265 – 290mOsm/kg b. 240 – 280mOsm/kg b. 275 – 295mOsm/kg
Serum osmolality in ADH ref range a. 265 – 290mOsm/kg b. 240 – 280mOsm/kg **b. 275 – 295mOsm/kg**