endometrial pathology Flashcards

(43 cards)

1
Q

causes PMB

A

vaginal atrophy // HRT // endometrial hyperpalsia // endometiral cancer // cervical, ovarian, vaginal cancer

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2
Q

most common cause PMB

A

vaginal atrophy

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3
Q

invx for all women over 55 + PMB

A

2 week USS for endometrial thickness

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4
Q

what endometrial thickness is worrying for cancer

A

5mm+

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5
Q

what are fibroids

A

benign smooth muscle tumours of uterus

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6
Q

who gets fibroids

A

black women, middle aged, in response to oestrogen

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7
Q

features fibroids

A

heavy periods (iron def) // lower abdo pain, painful periods, bloating // urinary if big // POLYCYTHAEMIA from EPO (rare)

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8
Q

invx fibroids

A

transvag USS

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9
Q

types of fibroid

A

submucosa (into uterine cavity) // subserosal (grow into abdomen on edge of uterus) // intramural (in myometrium)

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10
Q

mx asymptomatic fibroids

A

none needed - review

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11
Q

mx of menorrhagia from fibroids

A

levonestrogel IUS // mefenamic acid (NSAID) or tranexamic acid // COCP, POP, injection

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12
Q

medical mx fibroids

A

GnRH agonist to shrink (before surgery)

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13
Q

SE fibroid medical mx

A

menopausal symtpoms eg flushes, vaginal dryness // loss of bone mineral density

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14
Q

surgical mx fibroids

A

fibroid ablation // myomectomy (for childbearing) // hysterectomy // uterine artery embolism

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15
Q

complications fibroids

A

subfertility, iron def, red degeneration , torsion

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16
Q

when does fibroid degeneration tend to occur

A

in pregnancy (grows with oestroegen) –> baby outstrips their blood supply –> degeneration

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17
Q

symptoms fibroid degeneration

A

low fever, pain, vomiting

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18
Q

mx fibroid degeneration

A

bed rest and analgesia 4-7 days

19
Q

what is endometriosis

A

growth of endometrial tissue outside uterus

20
Q

symptoms endometriosis

A

pevic pain // secondary dysmennorhea (pain before period) // deep dyspareunia // subfertile // urinary symptoms // painful bowel

21
Q

invx endometriosis

A

(USS not v useful) // laparoscopy = gold

22
Q

1st line mx endometriosis

A

NSAIDs +/- paracetamol

23
Q

2nd line mx endometriosis

A

COCP or progesterones

24
Q

3rd line mx endometriosis

A

GnRh analogues (eg goserelin, danazol)

25
surgical mx endometriosis
lap excision or ablation + adhesiolysis (good for conception also)
26
only curative mx endometriosus
total hysterctomy
27
what is adenomyosis
endometrial tissue in myometrium
28
symptoms adenomyosis
dysmenorrhoea // menorrhagia // large, boggy uterus
29
invx adenomyosis
MRI
30
who usually gets adenomyosis
women with children in their 40s
31
mx adenomyosis
tranexamic acid // GnRH // uterine artery embolism // hysterectomy (definitive mx)
32
features endometrial hyperplasia
abnormal bleeding eg intermenstrual, post menopausal
33
mx simple endometrial hyperplasia w/o atypia
high dose progesterone (or IUS) --> repeat 3-4 months
34
mx endometrial hyperplasia + atypia
hysterectomy
35
types of endometrial hyperplasia
simple, complex, atypical
36
hormonal RF endometrial cancer
increased oestrogen - no kids, early menarche, late menopause,
37
meds RF endometrial cancer
unopposed oestrogen (eg HRT without progesterone) , tamoxifen
38
metabolic RF endometrial cancer
obesity // DM // PCOS
39
protective factors endometrial cancer
kids // COCP // smoking
40
symptoms endometrial cancer
PMB!!! // premenopausal = menorrhagia or intermentrual bleeding
41
invx for endometrial cancer
TVUS endometrial thickness (<4mm) // hysteroscopy with endometrial biopsy
42
mx endometrial cancer
TAH + BSO +/- post-op radio
43
complications hysterectomy
acute urianry retention // enterocele or vaginal vault prolapse