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Eukaryotes > Endoplasmic Reticulum > Flashcards

Endoplasmic Reticulum Flashcards

1
Q

ER was discovered by

A

Porter and Thompson

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2
Q

ER term was given by

A

Porter

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3
Q

Define ER.

A

It s a network of membrane bound tubes and sheets scattered in the cytoplasm.

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4
Q

What is ER connected to?

A

At one side, it is connected to the nuclear membrane ( outer membrane of nucleus).
The other end is present near PM ( may or may not be connected with PM)

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5
Q

What are the three forms of ER

A
  1. Cisternae
  2. Tubules
  3. Vesicles
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6
Q

Which form is ER is
Long, flattened sac like structure and actively involved in protein synthesis?

A

Cisternae
Eg: in brain and pancreas

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7
Q

Which form of ER is
Tube like structure, which could be branched or unbranched and involved in synthesis of lipid and sterol?

A

Tubules

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8
Q

Which form of ER is membrane bound sac like structure?

A

Vesicles
Eg : in spermatocytes

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9
Q

What is luminal compartment?

A

Space present inside ER

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10
Q

What is extra luminal compartment?

A

Space present outside ER

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11
Q

What are the types of ER

A
  1. Rough Endoplasmic Reticulum
  2. Smooth Endoplasmic Reticulum
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12
Q

Why is RER called granular ER?

A

Because of presence of Ribosomes

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13
Q

Larger subunit in the 80s ribosome is connected with the help of

A

Ribophorin

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14
Q

Which type of ER is proximal to nuclear membrane?

A

RER

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15
Q

Which type of ER is distal to nuclear membrane

A

SER

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16
Q

Which ER is involved in synthesis of protein?

A

Rough ER

17
Q

What are secretory proteins?

A

They are transported out of cell.

18
Q

What are membrane proteins?

A

The proteins that are used inside the cell.

19
Q

Which ER is involved in synthesis of lipids and sterol?

A

Smooth ER.

20
Q

Which ER is involved in detoxification of foreign compounds?

A

Smooth ER

21
Q

What are foreign compounds called as?

A

Xenobiotics
For eg:- drugs, medicines etc.

22
Q

What does cytochrome P450 do?

A

It converts lipid solubles into water solubles.

23
Q

How is contraction of muscles by SER caused?

A

By release and upstake of calcium ions

24
Q

What is involved in the synthesis of sphaerosomes and glyoxysomes?

A

Smooth ER

25
Q

RER associated with nerve cells

A

Nissl’s granules

26
Q

SER associated with retina

A

Myeloid bodies

27
Q

SER associated with muscle cells

A

Sarcoplasmic Reticulum

28
Q

ER associated with plasmodesmata

A

Desmotubules

29
Q

What is membrane biogenesis

A

Regeneration of Plasma Membrane

Eukaryotes (7 decks)

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