enoxaparin/lovenox Flashcards
(24 cards)
What is the classification of enoxaparin?
Enoxaparin is classified as a low molecular weight heparin (LMWH).
What is the usual adult dosage of enoxaparin for prophylaxis of deep vein thrombosis (DVT)?
The usual adult dosage for prophylaxis of DVT is 40 mg subcutaneously once daily.
How does enoxaparin work in the body?
Enoxaparin works by inhibiting factor Xa and to a lesser extent factor IIa in the coagulation cascade.
What is one primary indication for using enoxaparin?
One primary indication for enoxaparin is the prevention of thromboembolic disorders in patients undergoing surgery.
True or False: Enoxaparin can be used for both treatment and prevention of DVT.
True.
What is a common adverse effect of enoxaparin?
A common adverse effect of enoxaparin is bleeding.
Fill in the blank: Enoxaparin should be used with caution in patients with __________.
renal impairment.
What should be monitored regularly during enoxaparin therapy?
Anti-factor Xa levels should be monitored regularly during enoxaparin therapy.
What is the brand name of enoxaparin?
The brand name of enoxaparin is Lovenox.
What is the usual dosage of enoxaparin for the treatment of acute coronary syndrome?
The usual dosage for the treatment of acute coronary syndrome is 1 mg/kg subcutaneously every 12 hours.
True or False: Enoxaparin can be given intramuscularly.
False.
What is a significant drug interaction with enoxaparin?
A significant drug interaction with enoxaparin is with other anticoagulants, which can increase the risk of bleeding.
What is the route of administration for enoxaparin?
Enoxaparin is administered subcutaneously.
Fill in the blank: Patients receiving enoxaparin should be educated on signs of __________.
bleeding.
What laboratory test is often used to assess the effect of enoxaparin?
The anti-factor Xa assay is often used to assess the effect of enoxaparin.
What is the mechanism of action of enoxaparin?
Enoxaparin inhibits thrombin and factor Xa, leading to anticoagulation.
What is a contraindication for the use of enoxaparin?
A contraindication for the use of enoxaparin is active major bleeding.
True or False: Enoxaparin can be used during pregnancy.
True, but it should be used with caution and under medical supervision.
What is the half-life of enoxaparin compared to unfractionated heparin?
Enoxaparin has a longer half-life than unfractionated heparin.
What special population may require dosage adjustment of enoxaparin?
Patients with renal impairment may require dosage adjustment of enoxaparin.
What is the primary method of elimination for enoxaparin?
Enoxaparin is primarily eliminated by the kidneys.
Fill in the blank: Enoxaparin is often preferred over unfractionated heparin due to its __________.
predictable pharmacokinetics.
What should be done if a patient misses a dose of enoxaparin?
The patient should take the missed dose as soon as they remember, unless it is almost time for the next dose.
What is the primary goal of enoxaparin therapy?
The primary goal of enoxaparin therapy is to prevent thromboembolic events.
