Enzyme Inducers/inhibitors Flashcards

(45 cards)

1
Q

Carbamazepine

A

Induces Pgp, CYP 1A2/2C/3A, UGTs

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2
Q

Phenytoin

A

Induces Pgp, CYP 1A2/2C/3A, UGTs

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3
Q

Rifampin

A

Induces Pgp, CYP 1A2/2C/3A, UGTs

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4
Q

St. John’s Wort

A

Induces Pgp, CYP 3A

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5
Q

Ritonavir

A

Induces Pgp

Inhibits CYP 2D6/3A4

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6
Q

Tipanavir

A

Induces Pgp

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7
Q

Avasimbe

A

Induces Pgp

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8
Q

Phenobarbital

A

Induces CYP 1A2/2C/3A, UGTs

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9
Q

Felbamate

A

Induces CYP3A

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10
Q

Topiramate

A

Induces CYP3A

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11
Q

Oxcarbazepine

A

Induces CYP3A, UGTs

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12
Q

Griseofulvin

A

Induces CYP3A

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13
Q

Nevirapine

A

Induces CYP3A

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14
Q

Smoking

A

Induces CYP1A2

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15
Q

Alcohol

A

Induces CYP2E1

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16
Q

Lamotrigine

A

Induces UGTs

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17
Q

Oral contraceptives

A

Induces UGTs

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18
Q

Cyclosporin

A

Inhibits Pgp

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19
Q

Quinidine

A

Inhibits Pgp, CYP2D6

20
Q

Verapamil

21
Q

Amiodarone

A

Inhibits Pgp, CYP 1A2/2C9/2D6/3A4

22
Q

Erythromycin

A

Inhibits Pgp, CYP3A4

23
Q

Clarithromycin

A

Inhibits Pgp, CYP3A4

24
Q

Azithromycin

25
Diltiazem
Inhibits Pgp, CYP3A4
26
Ciproflaxacin
Inhibits CYP1A2
27
Cimetidine
Inhibits CYP 1A2/2D6
28
Ticlopidine
Inhibits CYP1A2
29
Fluvoxamine
Inhibits CYP 1A2/3A4
30
Fluconazole
Inhibits CYP 2C9/3A4
31
Ketoconazole
Inhibits CYP 2C9/3A4
32
Sulfamethoxazol
Inhibits CYP2C9
33
Isoniazid
Inhibits CYP2C9
34
Paroxetine
Inhibits CYP2D6
35
Sertraline
Inhibits CYP2D6
36
Fluoxetine
Inhibits CYP 2D6/3A4
37
Methadone
Inhibits CYP2D6
38
Indinavir nelfinavir
Inhibits CYP3A4
39
Amprenavir
Inhibits CYP3A4
40
Atazanavir
Inhibits CYP3A4
41
Saquinavir
Inhibits CYP3A4
42
Delavirdine
Inhibits CYP3A4
43
Nefazodone
Inhibits CYP3A4
44
Grapefruit juice
Inhibits CYP3A4
45
Seville orange juice
Inhibits CYP3A4