ENZYME INHIBITION

Question 1

is a molecule that sufficiently resembles an enzyme substrate in shape and charge distribution that it can
compete with the substrate for occupancy of the enzyme’s active site

Answer 1

competitive enzyme inhibitor

Question 2

is a substance that slows or stops the normal catalytic
function of an enzyme by binding to it

Answer 2

enzyme inhibitor

Question 3

is a molecule that decreases enzyme activity by
binding to a site on an enzyme other than the active site

Answer 3

noncompetitive enzyme inhibitor

Question 4

is a molecule that inactivates enzymes by forming a
strong covalent bond to an amino acid side-chain group at the enzyme’s active site

Answer 4

irreversible enzyme inhibitor

Question 5

A molecule closely resembling the substrate. Binds to the active site and temporarily prevents substrates from
occupying it, thus blocking the reaction.

Answer 5

Competitive Enzyme Inhibitor

Question 6

A molecule that binds to a site on an enzyme that is not the active site. The normal substrate still occupies the active site but the enzyme cannot catalyze the
reaction due to the presence of the inhibitor

Answer 6

Noncompetitive Enzyme Inhibitor

Question 7

A molecule that forms a covalent bond to
a part of the active site, permanently
preventing substrates from occupying it

Answer 7

Irreversible Enzyme Inhibitor