enzyme table Flashcards

(134 cards)

1
Q

what is the enzyme group of this enzyme: Salivary α-amylase

A

Glycosidase
Endoglycosidase

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2
Q

what is the specific activator of this enzyme: Salivary α-amylase

A

Cl-

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3
Q

what is the substrate of this enzyme: Salivary α-amylase

A

Starch, glycogen

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4
Q

what is the action mechanism of this enzyme: Salivary α-amylase

A

Hydrolysis of internal
α 1,4 glycosidic bonds

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5
Q

potential products of this enzyme: Salivary α-amylase

A

Dextrins, maltotriose, maltose,
isomaltose

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6
Q

what is the pH of saliva?

A

6.8 – 7.2

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7
Q

where do we find this enzyme? Salivary α-amylase

A

Salivary/lingual
glands

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8
Q

what is the enzyme group of this enzyme: Lingual lipase (characteristic for newborns,
infants)

A

Esterase

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9
Q

what is the specific activator of this enzyme: Lingual lipase

A

none

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10
Q

what is the substrate of this enzyme: Lingual lipase

A

Triacylglycerides

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11
Q

what is the action mechanism of this enzyme: Lingual lipase

A

Hydrolysis of ester bonds

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12
Q

potential products of this enzyme: Lingual lipase

A

Fatty acids, 1,2-diacylglycerols,
rarely monoacylglycerols

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13
Q

where do we find this enzyme? lingual lipase

A

in Salivary/lingual glands

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14
Q

what is the pH of gastric juice?

A

1-2 (acidic)

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15
Q

what is the enzyme group for pepsin?

A

peptidase, endopeptidase

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16
Q

what is the specific activator for pepsin?

A

HCl, autocatalysis

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17
Q

what is the substrate for pepsin?

A

proteins

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18
Q

what is the action mechanism for pepsin?

A

Hydrolysis of peptide
bonds after aromatic AA
(Phe, Tyr, Trp)

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19
Q

potential products of pepsin?

A

Polypeptides, oligopeptides,
tripeptides, dipeptides

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20
Q

what is the optimum pH for Gastric lipase?

A

4-6

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21
Q

what is the enzyme group for Gastric lipase?

A

esterase

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22
Q

specific activator for Gastric lipase?

A

none

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23
Q

substrate for Gastric lipase?

A

Triacylglycerides

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24
Q

action mechanism for gastric lipase

A

Hydrolysis of ester bonds

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25
potential products for gastric lipase:
Fatty acids, 1,2-diacylglycerols, rarely monoacylglycerols
26
which kind of cells do we have in the stomach?
chief cells
27
which kind of cells do we have pancreas?
acinar cells
28
where do we find the enzyme pepsin?
in stomach
29
where do we find the enzyme gastric lipase?
in stomach
30
what is the enzyme group for Pancreatic α-amylase?
Glycosidase Endoglycosidase
31
what is the specific activator for Pancreatic α-amylase?
Cl-, Ca2+ (for stabilization of active site)
32
what is the substrate for Pancreatic α-amylase?
Starch, glycogen
33
action mechanism for Pancreatic α-amylase?
Hydrolysis of internal α 1,4 glycosidic bonds
34
potential products for Pancreatic α-amylase?
Dextrins, maltotriose, maltose, isomaltose
35
what is the specific activator for Trypsin?
Enterokinase (enteropeptidase) and trypsin
36
what is the enzyme group for trypsin?
peptidase, endopeptidase
37
substrate for trypsin?
Proteins, peptides
38
action mechanism for trypsin?
Hydrolysis of internal peptide bonds after basic AA (Arg, Lys, but NOT His)
39
potential products for trypsin?
Shorter polypeptides, peptides
40
where do we find trypsin?
in the pancreas
41
where do we find Pancreatic α-amylase?
in pancreas
42
where do we find chymotrypsin?
in pancreas
43
what is the pH of pancreatic juice?
7.6-8.3
44
what is the enzyme group of chymotrypsin?
peptidase, endopeptidase
45
specific activator for chymotrypsin?
Trypsin – proteolytical cleavage
46
substrate for chymotrypsin
Proteins, peptides
47
action mechanism for chymotrypsin
Hydrolysis of internal peptide bonds after aromatic AA (Phe, Tyr, Trp)
48
potential products for chymotrypsin
Shorter polypeptides, peptides
49
where do we find elastase?
in pancreas
50
what is the enzyme group for elastase?
peptidase, endopeptidase
51
specific activator of elastase
Trypsin – proteolytical cleavage
51
substrate of elastase
Proteins (polypeptides), peptides
52
action mechanism of elastase
Hydrolysis of internal peptide bonds after short AA (Ser, Thr, Ala, Gly, Cys)
53
potential products of elastase
Shorter polypeptides, peptides
54
enzyme group of Carboxypeptidase A
Peptidase, Exopeptidase
55
specific activator of Carboxypeptidase A
Trypsin – proteolytical cleavage
56
substrate of Carboxypeptidase A
Proteins (polypeptides), peptides (smallest tripeptide)
57
where do we find Pancreatic lipase?
in pancreas
58
what is the enzyme group of Pancreatic lipase?
esterase
59
what is the substrate of pancreatic lipase?
Triacylglycerides
60
what is the action mechanism of pancreatic lipase?
Hydrolysis of ester bonds
61
what is the potential products of pancreatic lipase?
Fatty acids, monoglycerols glycerol
62
what is the enzyme group for Pancreatic lipase related protein-2?
esterase
63
what is the substrate for pancreatic lipase?
Triacylglycerides, galactolipids, phospholipids
64
what is the action mechanism for pancreatic lipase?
Hydrolysis of ester bonds
65
what is the potential products of pancreatic lipase?
Fatty acids, monoacylglycerols, monoacylgalactosylglycerol, monoacylphosphoglycerol
66
what is the enzyme group for Carboxyl ester lipase?
esterase
67
what is the substrate for carboxyl ester lipase?
Triglycerides, galactolipids, phospholipids, cholesterol esters
68
what is the action mechanism for carboxyl ester lipase?
Hydrolysis of ester bonds
69
what is the potential products of carboxyl ester lipase?
Fatty acids, monoacylglycerols, monoacylgalactosylglycerol, monoacylphosphoglycerol cholesterol
70
what is the enzyme group for Phospholipase A2?
Esterase
71
what is the substrate for phospholipase A2?
Phospholipids
72
what is the action mechanism for phospholipase A2?
Hydrolysis of ester bonds
73
potential products for phospholipase A2?
Fatty acids, monophosphoglycerol
74
the enzyme group for Polynucleotidase: Ribonuclease Deoxyribonuclease?
Esterase
75
substrate for Polynucleotidase: Ribonuclease Deoxyribonuclease
RNA - polynucleotides DNA - polynucleotides
76
action mechanism for Polynucleotidase: Ribonuclease Deoxyribonuclease?
Hydrolysis of phosphodiester bonds between nucleotides
77
potential products for Polynucleotidase: Ribonuclease Deoxyribonuclease?
Oligonucleotides, mononucleotides
78
which kind of cells do we find in the intestinal mucose?
absorptive cells
79
enzyme group for Glucoamylase?
Glycosidase, Exoglycosidase
80
substrate for glucoamylase
Oligosaccharides, dextrins, maltotriose, maltose
81
action mechanism for glucoamylase
Hydrolysis of terminal α-1,4- glycosidic bonds at nonreducing end
82
potential products for glucoamylase
Shorter oligosaccharide, Glucose
83
enzyme group for β – glycosidase complex?
Glycosidase, Exoglycosidase
84
substrate for β – glycosidase complex
Lactose, cellobiose, glycosyl-β-ceramides
85
action mechanism for β – glycosidase complex
Hydrolysis of β 1,4 glycosidic bond
86
potential products for β – glycosidase complex
Glucose and galactose
87
enzyme group for Sucrase-isomaltase complex
Glycosidase, Exoglycosidase
88
substrate for Sucrase-isomaltase complex
Dextrins, maltose, maltotriose, isomaltose, sucrose
89
action mechanism for Sucrase-isomaltase complex
Hydrolysis of α 1,2; both α-1,4- and α-1,6-glycosidic bonds
90
potential products for Sucrase-isomaltase complex
Glucose; fructose, shorter oligoscahharides
91
enzyme group for Trehalase
glycosidase, exoglycosidase
92
substrate for trehalase
trehalose
93
action mechanism for trehalase
Hydrolysis of α 1,1-glycosidic bonds
94
potential products for trehalase
Glucose
95
enzyme group for nucleosidase
glycosidase
96
substrate for nucleosidase
nucleoside
97
action mechanism for nucleosidase
hydrolysis of N-glycosidic bond
98
potential products for nucleosidase
Pentose (ribose or deoxyribose); purine or pyrimidine base
99
enzyme group for aminopeptidase
peptidase, exopeptidase
100
substrate for aminopeptidase
peptide (smallest tripeptide)
101
action mechanism for aminopeptidase
hydrolysis of any AA from N terminal
102
potential products of aminopeptidase
shorter peptide and amino acid
103
enzyme group of dipeptidase
peptidase, exopeptidase
104
substrate for dipeptidase
dipeptides
105
action mechanism for dipeptidase
Hydrolysis of any dipeptide
106
potential products of dipeptidase
amino acids
107
enzyme group of nucleotidase
esterase
108
substrate of nucleotidase
nucleotide
109
action mechanism for nucleotidase
hydrolysis of ester bonds in nucleotide
110
potential products of nucleotidase
nucleoside and phosphate
111
enzyme group of Carboxypeptidase B
Peptidase, Exopeptidase
112
specific activator of Carboxypeptidase B
Trypsin – proteolytical cleavage
113
substrate of Carboxypeptidase B
Proteins (polypeptides), peptides (smallest tripeptide)
114
action mechanism of Carboxypeptidase B
Hydrolysis of basic (Arg, Lys, but NOT His) from carboxy-terminal end
115
potential products of Carboxypeptidase B
Shorter peptide (smallest dipeptide) AND amino acid
116
where do we find nucleotidase?
intestinal mucosa
117
where do we find dipeptidase
intestinal mucose
118
where do we find aminopeptidase
intestinal mucosa
119
where do we find nucleosidase
intestinal mucosa
120
where do we find trehalase
intestinal mucosa
121
where do we find ssucrase-isomaltase complex
intestinal mucosa
122
where do we find β – glycosidase complex?
intestinal mucosa
123
where do we find glucoamylase?
intestinal mucosa
124
where do we find Polynucleotidase: Ribonuclease Deoxyribonuclease?
in pancreas
125
where do we find Phospholipase A2
in pancreas
126
where do we find Carboxyl ester lipase?
in pancreas
127
where do we find Pancreatic lipase related protein-2?
in pancreas
128
where do we find Pancreatic lipase?
in pancreas
129
where do we find Carboxypeptidase B?
in pnacreas
130
where do we find Carboxypeptidase A?
in pancreas
131
where do we find Elastase?
in pancreas
132
action mechanism of Carboxypeptidase A
Hydrolysis of aromatic AA (Phe, Tyr, Trp) from carboxy-terminal end
133
potential products of Carboxypeptidase A
Shorter peptide (smallest product dipeptide) AND amino acid