Enzymes III: Enzyme Inhibitions and Regulations

Question 1

Define what is an inhibitor

Answer 1

Molecule which acts directly on an enzyme to lower its catalytic rate

Question 2

State the main types of enzyme inhibition

Answer 2

1) Reversible inhibition
- can be overcome by removing the inhibitor from the enzyme (eq: by dialysis)
2) Irreversible inhibition
- can’t be overcome since the inhibitors will permanently bounded to the enzyme

Question 3

Explain how does enzyme being regulated?

Answer 3

Enzymes are regulated by either increasing or reducing their activity by the addition of activators or inhibitors

Question 4

State the 4 mechanism types of enzyme regulation

Answer 4

a) Feedback Regulation
b) Allosteric Regulation
c) Reversible Covalent Modification
d) Proteolytic Activation