Epidemiology Flashcards
(15 cards)
SUD
- ALL SUD 22%
- EtOH 18% (10% lifetime risk)
- Cannabis 7%
- 4%: Cocaine > Opioids (1%), etc. Substance use in genpop.:
Caffeine > EtOH (>90%) > Nicotine (13%; 65% in SCZ) > Cannabis > others
*Note: EtOH + BZD use peaks at 65-74 yo
Anxiety
- ALL anxiety D/O/: 31% (most common D/O) … 20% in peripartum women
- Separation anxiety: (most common in < 12yo)
- Specific phobia: 13% (most common anxiety D/O)
- Social anxiety: 12%
- Selective mutism
- Panic disorder: 6% (vs PA in 40% in genpop)
- Agoraphobia: (50% in panic D/O)
- Generalized anxiety: 6%
- Obsessive compulsive D/O: 3% (tic-related 30%)
- Post-traumatic stress D/O: 9% (vs trauma in 75% in genpop)
- Acute stress D/O: (50% of PTSD had ASD)
Bipolar
~1% ; 1/3 have their 1st mood episode <18 yo
Dx can be delayed > 10 yr; misdiagnosis (28% MDD > BAD); over diagnosed in BPD, ADHD, SUD
Depression
~ 12% lifetime risk (~12% peripartum onset period as well)
2nd cause of global disability
Suicide risk increases by 5x in 1mo before initiating, after initiating and after D/C of AD
- 50% of people who die of suicide have MDD
~ 30% of MDD > PDD, which has a slower response rate and is less likely to remit
Comorbidity: ADHD, SUD, Anxiety D/O ~ 60%, GMC (RF for CAD, CVA, epilepsy, DM, cancer, HIV)
Cannabis-use: ~6-50% in MDD -> Associated w/ worsening course and Sx
Late-onset MDD: Worse prognosis, more chronic, higher relapse, higher comorbidity, cognitive impairment and mortality. *vascular, ?prodrome dementia, executive dysfunction, not responsive to AD
ID
ASD
ADHD
SLD
- ID: ~1%
- ASD: ~1% 4M:F
- ADHD: ~5-9% children, ~3-5% adults; M>F
>60% on children will have ADHD as adults (not related to response to Tx) - SLD: 10%; 3M:F
ODD
Conduct d/o
- ODD: 3.3%; M>F in childhood, then M=F
- Conduct D/O: 4%
Somatic d/o
Illness anxiety
functional neurological d/o
somatic: ~5-7% F=M
Illness anxiety: ~4-6% F=M
F>M
Comorbid neuro condition common (1/3), panic d/o, MDD, SSD, ASPD, HPD
Psychotic disorders
~1% ; M: 24yo, W: 28yo
Course:
Antipsychotics Responsive: 50% adequate; 30% partial
Suicide: Lifetime death by suicide ~10% (50% SA); annual 1%; SA
- Highest risk: early onset, early recovery phase
Prognosis:
Total recovery: 14%; Employed at some point: <30%; Marriage: <30%
Sx remission within 1 yr of treatment: 90%
Relapse by 5 yr follow-up: 85% (5x higher risk if not treated)
High risk of relapse post FEP is medication stopped within 2 yrs
- Substance-use: 47% comorbidity with SUD (excluding nicotine (60-90%), caffeine)
Most common SUD: Alcohol, Cannabis
- LAI reduces relapse (6x in 1 yr follow-up ; 1/3 re-hospitalization over 7 yrs)
Insomnia
13.5%
Breathing related sleep d/o
1-2% C&A
2-15% adults
>20% elderly
Circadian rhythm sleep-wake D/O
Delay (teens); Adanced (elders); Irreg. (MNCD); Non-24hr (VI); Shift-work
Delayed: 7%
Advanced: 1%
Irregular: MNCD
Non-24hr: 50% blind
Shift-work: 5-10%
MCI
10-20% above 65
10% convert per year
Anorexia
Anorexia nervosa 1% ; subthreshold 0.5%
Bulimia
Bulimia nervosa 1-4% , later onset than AN