Epidemiology Flashcards

1
Q

What is epidemiology?

A
  • The study of populations in order to determine the frequency and distribution of disease
  • (it helps in identifying risk factors for disease and determining optimal treatment approaches to clinical practice and preventative medicine)
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2
Q

What are the major roles of epidemiology? (7 points)

A
  • Monitor infectious and non-infectious diseases
  • Study natural history of diseases
  • Investigation of disease risk factors
  • Health care needs assessment
  • Development of preventative programmes
  • Evaluation of interventions
  • Health service planning
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3
Q

One major role of epidemiology is to study the natural history of diseases. What are the groupings of these? (4 points)

A
  • Self-limiting
  • Chronic
  • Fatal
  • Unknown
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4
Q

One major role of epidemiology is for health needs assessment. This is what care services are required by particular groups. What is this dependent on?

A
  • The health status and demographics of the population
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5
Q

One major role of epidemiology is the development of preventative programmes. What is this based on?

A

Knowing risk factors of diseases and attempting to prevent exposure to these factors

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6
Q

What are the 3 main types of epidemiological study?

A
  • Descriptive (observational)
  • Analytic (observational - case control or cohort)
  • Intervention/experimental
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7
Q

What are 2 terms that are a measure of disease frequency?

A
  • Prevalence

- Incidence

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8
Q

What is meant by the term ‘prevalence’?

A
  • A measurement of ALL individuals affected by the disease within a particular period of time or point in time
  • It is the number of existing cases in a population
  • Number of affected individuals (cases) divided by the total number of persons in the population
  • Prevalence estimates are obtained from cross-sectional studies or derived from registers
  • It is used as an estimate of how common a condition is within a population over a certain period of time or point in time
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9
Q

What is meant by the term ‘incidence’?

A
  • A measurement of the number of NEW individuals who contract a disease during a particular period of time
  • Number of new cases or events during a specific period of time in a defined population
  • Incidence estimates obtained from longitudinal studies or derived from registers
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10
Q

Why might a chronic incurable disease like diabetes have a low incidence but a high prevalence?

A

Because the prevalence in the cumulative sum of the past year incidence rates

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11
Q

Why might a short duration curable condition such as the common cold have a high incidence but a low prevalence?

A

Because many people get a cold each year, but few people actually have a cold at any given time (so prevalence is low)

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12
Q

In descriptive studies the main variables broadly fall into 3 categories. What are these categories?

A
  • Time
  • Place
  • Person

OR

  • Where
  • When
  • Who
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13
Q

When sampling a population for a survey, is it necessary to study the whole population to obtain valid information about that population?

A
  • No
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14
Q

What are the advantages of sampling as a survey method? (4 points)

A
  • Reduces no. of individuals to be sampled
  • Reduces cost
  • Higher response rate
  • Higher quality of information collected
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15
Q

Why must a sample be representative of the population being investigated?

A
  • As this aims to avoid bias
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16
Q

What are 5 sampling techniques?

A
  • Simple random sample
  • Systematic sample
  • Stratified sample
  • Cluster sample
  • Multi-stage sampling
17
Q

What is the ‘simple random sampling’ technique?

A

For example - use of a table of random numbers

18
Q

What is the ‘systematic sample’ technique?

A
  • individuals selected at regular intervals from a population list
19
Q

What is the ‘Stratified sample’ technique?

A
  • Ensure small sub-groups are adequately represented
20
Q

What is the ‘cluster sample’ technique?

A
  • Use of groups as sampling units e.g. school classes
21
Q

What is the ‘multi-stage sampling’ technique?

A
  • Combines all of the other sampling techniques (simple random sample, systematic sample, stratified sample, cluster sample)
22
Q

What are possible forms of error or bias in survey methodology? (5 points)

A
  • Sampling bias/selection bias
  • Response bias/information bias
  • Measurement error
  • Observer variation (intra- or inter-)
  • Loss to follow up
23
Q

What are the properties of an ideal index? (9 points)

A
  • Clear, unambiguous, non subjective
  • Ideally correspond with clinically important stages of the disease
  • Indicate treatment need
  • Within the ability of examiners
  • Reproducible
  • Not time-consuming
  • Acceptable to patient
  • Amendable to statistical analysis
  • Allow comparison with other studies
24
Q

What are the limitations of the DMF (decayed, missing and filled teeth) index? (6 points)

A
  • Teeth extracted for reasons other than caries
  • Influenced by access e.g. interproximal surface
  • Difficulty in differentiating fissure-sealant from restorations - underestimate caries
  • Influenced y past disease activity
  • Threshold criteria of disease can vary (must specify)
  • Cannot be used for root caries