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Pharmacology > Epilepsy /anticonvulsant > Flashcards

Epilepsy /anticonvulsant Flashcards

1
Q

Epilepsy is a condition that results from

A

Too much excitatory amines at the cns

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2
Q

Mechanism of anticonvulsant include

A

Increase of gaba at
Increase outward movement of K+ efflux
Decrease in glutamate
Inhibiting na+ and ca+ channel

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3
Q

Major excitatory protein of the cns is

A

Glutamate

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4
Q

GABA a receptor does

A

Influx of chlorine

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5
Q

Barbiturate mechanism of action is

A

Acting upon GABA a receptor inducing an influx of chlorine cl-

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6
Q

Barbiturates and benzodiazepines mechanism of action is

A

Attaching to GABA A and causing an influx of chlorine into the cell

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7
Q

What are barbiturates

A

They are cns depressants that cause drowsiness

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8
Q

Longest acting barbiturates is

A

Phenobarbital

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9
Q

Immediate/ partial long acting barbiturates is

A

Pentobarbital

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10
Q

Short acting barbiturates is

A

Secobarbital

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11
Q

Benzodiazepines are what type of cns drug

A

Anxiolytics (anti anxiety drugs

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12
Q

Effect of barbiturates to REM

A

Barbiturates increases REM 2 phase and
Decreases REM 3,4&5

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13
Q

Benzodiazepines drugs end in
( LAM & PAM)

A

Eg dizepam, Midazolam, lorazepam

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14
Q

Short acting benzodiazepines is

A

Midazolam
Triazolam

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15
Q

Long acting benzodiazepines is

A

Diazepam
Flurazepam

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16
Q

Intermediate acting benzodiazepines is

A

Lorazepam
Alfrazolam
Temazepam

17
Q

Flumazenil is an antitode for overdose of benzodiazepines

A
18
Q

What drug is sued to treat overdose ofbenzodiazepines

A

flumazenil

Pharmacology (24 decks)

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