Epilepsy + Seizures Flashcards

1
Q

What is Epilepsy definition?

A

Umbrella term for a collection of seizures where there are episodes of abnormal electrical activity

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2
Q

What are the 2 main investigations with px with Epilepsy

A

MRI

Electroencephalography (EEG)

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3
Q

what are 2 types of Epilepsy’s that occur in adults

A

Generalised Tonic-Clonic seizure

Focal Seizure (“temporal”)

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4
Q

What are the 3 types of Epilepsy that occur in children

A

Absence Seizure (“Blank”)

Atonic Seizure (“Drop Attacks”)

Myoclonic Seizure (“Jump”)

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5
Q

What are the 3 stages in a Generalised Tonic-Clonic Seizure

A

Muscle Tensing (Tonic)

Muscle Jerking (Clonic)

Postictal Period (drowsiness after seizure)

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6
Q

What 4 symptoms can arise with a generalised tonic-clonic seizure that doesn’t include the tonic/clonic part

A

Tongue Biting

Incontinence

Groaning

Irregular Breathing

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7
Q

what is the 1st and 2nd line treatment in a Generalised Tonic-Clonic Seizure

A

1st ==> Sodium Valproate

2nd ==> Carbamazepine

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8
Q

Where does focal seizures affect in the head?

What can this lead to (4)

A

Temporal Lobes

==> Memory affected
==> Speech affected

==> Hallucinations
==> Deja Vu

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9
Q

What is the 1st and 2nd line treatment in a focal seizure (temporal)

A

1st ==> Carbamazepine

2nd ==> Sodium Valproate

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10
Q

In an absence seizure, how long does the child typically stare into space for?

A

10-30s

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11
Q

Treatment for Absence seizures?

A

Sodium Valproate

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12
Q

Atonic Seizure in Children is caused by what?

A

Brief lapses in muscle tone => randomly falling over

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13
Q

What are Atonic Seizures potentially indicative of (syndrome)?

A

Lennox-Gastaut Syndrome

==> Brain injury that results in children having seizures

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14
Q

Myoclonic Seizures leads to what happening in children?

A

Brief muscle contraction ==> Randomly jump up

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15
Q

Myoclonic seizures is potentially indicative of what (Syndrome)

A

Juvenile Myoclonic Epilepsy

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16
Q

What are the 1st + 2nd line treatments for Myoclonic Seizures + Atonic Seizures

A

1st ===> Sodium Valproate

2nd ===> Lamotrigine

17
Q

How does Sodium Valproate work/

A

Increases GABA by reducing GABA metabolism

More GABA => relaxes brain as it inhibits neuronal activity

18
Q

Which type of people is Sodium Valproate avoided in?

Why?

A

Pregnant Women

Highly Teratogenic

19
Q

Status Epilepticus is what?

A

Medical emergency that can lead to permanent brain injury / death

20
Q

Status Epilepticus is defined as having what (2)

A

Seizure >5mins

> 3 seizures in 1hour

21
Q

What is given in Status Epilepticus?

A

IV Lorazepam