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ClinPhar II Lec > Epilepsy table > Flashcards

Epilepsy table Flashcards

1
Q

First-Line Drugs for Newly Diagnosed
(Adults and Adolescents)

A

Carbamazepine
Gabapentin
Oxcarbazepine
Phenobarbital
Topiramate
Valproic Acid

(CarGO - PTV)

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2
Q

Alternative Drugs (FDA-Approved) for Newly Diagnosed (Adults and Adolescents)

A

Carbamazepine
Lacosamide
Phenobarbital
Phenytoin
Topiramate

(CarLa, PhePhe To?)

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3
Q

1st line: Refractory Monotherapy

A

Lamotrigine
Oxcarbazepine
Topiramate

(LOT)

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4
Q

Alternative: Refractory Monotherapy

A

Carbamazepine
Lamotrigine
Oxcarbazepine
Phenobarbital
Phenytoin
Topiramate
Valproic Acid

(CarLa, PhePhe Va TO)

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5
Q

1st line: Refractory Adjunct

A

Gabapentin
Lamotrigine
Levetiracetam
Oxcarbazepine
Tiagabine
Topiramate
Zonisamide

(GaLa Tia LeO ToZ)

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6
Q

Alternative: Refractory Adjunct

A

Carbamazepine
Gabapentin
Lamotrigine
Levetiracetam
Oxcarbazepine
Phenobarbital
Phenytoin

(CarGa LaLeO PhePhe)

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7
Q

1st line: Children

A

Gabapentin
Lamotrigine
Oxcarbazepine
Topiramate

(GaLa TO)

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8
Q

Alternative: Children

A

Pregabalin
Tiagabine
Valproic
Vigabatrine
Zonisamide

(Pre, Tia Val VigaZ)

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9
Q

1st line: Generalized seizures absence (newly diagnosed)

A

Lamotrigine

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10
Q

Alternative: Generalized seizures absence (newly diagnosed)

A

Ethosuximide, Valproic
Acid

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11
Q

1st line: Primary generalized (tonic clonic)

A

topiramate

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12
Q

Alternative: Primary generalized (tonic clonic)

A

Lamotrigine, Levetiracetam

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13
Q

Alternative: Juvenile myoclonic epilepsy

A

Levetiracetam
(myoclonic seizures)

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14
Q

Cause fewer cognitive impairments

A

Gabapentin and
Lamotrigine

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15
Q

May cause substantial cognitive
impairments especially at high
doses or in rapid-dose escalation

A

Topiramate

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16
Q

Most widely used AEDs

A

Carbamazepine,
Phenobarbital,
Phenytoin,
Valproic Acid

17
Q

uperior to valproic acid for efficacy
in the treatment of partial seizures

A

Carbamazepine

18
Q

Newer generation agents
● Received FDA approval for use as
monotherapy in patients with partial
seizures

A

Lamotrigine,
Oxcarbazepine,
Topiramate

19
Q

traditional treatment

A

Phenytoin

20
Q

increasingly used due to lower
incidences of side effects

A

Carbamazepine and Valproic acid

21
Q

Tonic-Clonic
Seizures

A

Carbamazepine and Valproic acid and Phenytoin

22
Q

Generally considered the drug of
first choice for atonic seizures and
for juvenile myoclonic epilepsy
(JME)

A

Valproic acid

23
Q

Alternative agents

A

Lamotrigine,
Topiramate,
Zonisamide

24
Q

FDA-approved as adjunctive
treatment of myoclonic seizures in
patients with JME

A

Levetiracetam

ClinPhar II Lec (6 decks)

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