Epithelia Flashcards

(28 cards)

1
Q

What are the 2 types of epithelia?

A
  1. Covering epithelia

2. Glandular epithelia

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2
Q

What is the difference between endocrine and exocrine glands?

A

Exocrine glands have ducts. Endocrine glands don’t have ducts but secrete hormones directly into the bloodstream

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3
Q

Example of exocrine gland

A

Sweat gland, salivary gland

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4
Q

In the classification of epithelia, what is one layer of cells called?

A

Simple epithelium

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5
Q

What are multiple layers of cells called?

A

Stratified epithelium

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6
Q

What is benefit of stratified epithelium?

A

Protective: the higher the number of layers the more protective it is at withstanding abrasion

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7
Q

What is pseudo-stratified?

A

Single layer of cells but the nuclei are at different heights, so it looks like more than one layer

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8
Q

What are transitional epithelia?

A

The cells can alter their shape

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9
Q

How do squamous cells look?

A

Cells are flat: width is much greater than the height

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10
Q

How do cuboidal cells look?

A

Cells appear approx square

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11
Q

How do columnar cells look?

A

Cells are tall: height is greater than width

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12
Q

What is shape and structure of epithelia involved in gas exchange? Why?

A

Single layer of squamous cells i.e. simple. squamous

Minimal distance for gaseous diffusion

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13
Q

Some cells have specialisations. What is purpose of microvilli?

A

Increase the surface area of epithelium available for absorption.

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14
Q

Where are microvilli most developed?

A

In cells specialised for absorption e.g. intestinal cells

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15
Q

What is purpose of keratin?

A

In the skin, basal cells start to divide and move out into layers above where they start to lose their nuclei and degenerate. These cells finally flake off from apical surface

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16
Q

Where is keratin mostly found?

A

In areas susceptible to abrasion and water loss (skin). Layers of the immediate protein keratin are found on the apical surface

17
Q

What is classification of cells found in oesophagus?

A

Non-keratinised stratified squamous epithelium

  • Does not need layer of keratin for protection against drying out
  • Many layers: protective
18
Q

What is purpose of cilia and where are they found?

A

Beat synchronously. Found on cells lining upper respiratory tract, rhythmic beating moves mucus upwards

19
Q

What are the 3 methods of secretion of exocrine secretion?

A

Merocrine, Holocrine, Apocrine

20
Q

What happens during holocrine?

A

Secretory product accumulates in cytoplasm. Whole cell ruptures to release product

21
Q

What is example of holocrine secretion?

A

Sebum in sebaceous glands

22
Q

What happens during merocrine secretion?

A

Most common form of secretion

  1. Product produced inside intra-cellular vesicle which travels up to surface
  2. Fusing with cell membrane. 3. Product released by exocytosis
  3. Fused plasma membrane recycled by endocytosis
23
Q

What is example of merocrine secretion?

A

Most sweat glands, pancreas

24
Q

What happens during apocrine?

A
  1. Product in vesicle

2. Vesicle approaches apical membrane which pinches off with some loss of apical membrane

25
What is Cystic Fibrosis caused by?
Defective chloride channel on apical surface of epithelial cells
26
What is result of this defect?
Affects lungs and exocrine glands Mucus that epithelial layers secrete doesn't have enough water - thickened up so builds up and cannot be expelled
27
What is Epidermolysis Bullosa caused by?
Gene mutation of adhesion molecules that stick epithelium to basement membrane
28
What is result of this mutation?
Abnormal anchoring of epidermis to dermis: blistering skin disorder