Epithelial Ovarian Tumors Flashcards

1
Q

Epithelial ovarian tumors are the most common type. At what age do they present?

A

20+

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2
Q

What are the 5 subtypes of Epithelial Ovarian tumors?

A
  • Serous
  • Mucinous
  • Endometrioid
  • Clear cell
  • Transitional cell
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3
Q

What are the 5 subtypes of Epithelial Ovarian tumors?

A
  • Serous
  • Mucinous
  • Endometrioid
  • Clear cell
  • Transitional cell
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4
Q

What are the 3 classifications of Epithelial Ovarian tumors?

A

Benign
Borderline
Malignant

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5
Q

A cystic benign epithelial tumor

A

Cystadenoma

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6
Q

A cystic and fibrous benign epithelial tumor

A

Cystadenofibroma

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7
Q

A fibrous benign epithelial tumor

A

Adenofibroma

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8
Q

Serous Epithelial tumors can be what 2 grades?

A

Low grade

High grade

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9
Q

Low grade serous epithelial tumor

A

Cystic with tubal epithelium and papillary growth

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10
Q

High grade serous epithelial tumor

A

Solid tumor with atypia

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11
Q

A High grade serous epithelial tumor is associated with what mutations?

A

TP53

BRCA1 and 2

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12
Q

What type of epithelium do Mucinous Epithelial tumors have?

A

Columnar

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13
Q

Mucinous Epithelial tumors are unilateral or bilateral?

A

Unilateral

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14
Q

What mutation is associated with Mucinous Epithelial tumors?

A

KRAS

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15
Q

Unilateral cystic lesion with columnar epithelium

A

Mucinous tumor

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16
Q

What is often a precursor for an Endometrioid Epithelial tumor?

A

Endometriosis

17
Q

Most Endometrioid and Clear cell Epithelial tumors are _____

A

Carcinomas

18
Q

What histo attributes are present with Clear Cell Epithelial tumors?

A

Large epithelial cells with clear cytoplasm

19
Q

Transitional cell tumor alternate name

A

Brenner tumor

20
Q

What type of epithelium is present with a Brenner tumor?

A

Urothelial type transitional epithelium

21
Q

Brenner tumors are usually malignant or benign?

A

Benign

22
Q

Urothelial type transitional epithelium

A

Brenner tumor

23
Q

Large cells with clear cytoplasm

A

Clear cell tumor

24
Q

KRAS mutations

A

Mucinous tumor

25
Q

P53, BRCA 1 and 2 mutations

A

Serous tumor (high grade solid tumor)