Epithelial Tissue Flashcards Preview

Module 1: Lecture > Epithelial Tissue > Flashcards

Flashcards in Epithelial Tissue Deck (27):
1

Describe the functions of epithelia

line cavities and cover surfaces, separate 2 distinct domains while interacting with the contents of each domain

2

Describe the characteristics of epithelial cells

tightly packed together, form avascular sheets, attached to a basement membrane, sit on underlying connective tissue, have polarity (apical and basal regions)

3

Name the two kinds of apical surface modifications

microvilli, cilia

4

Function of microvilli?

to increase surface area of hte cell

5

Microvilli have what kind of filaments to give them structure and anchor?

Actin filaments

6

Function of cilia?

move fluid and particles along epithelial surfaces

7

Cilia have what to give them structure?

Microtubules

8

What anchors cilium to the cytoskeleton?

Basal body

9

3 kinds of lateral surface modifications?

occluding junctions, anchoring junctions, communicating junctions

10

Describe occluding junctions

tight junctions, seal membranes together

11

Occluding junctions are formed by what two transmembrane proteins

occluding, claudin

12

Describe anchoring junctions

zonula adherens provide lateral adhesion (hold cells together); macula adherens = desmosome, spotlike junction

13

Zonula adherens consist of what 2 proteins? that link to?

Cadherins, integrins; actin filaments of cytoskeleton

14

Describe communicating junctions?

Gap junctions permit passage of molecules

15

gap junctions are made of what protein family?

Connexin proteins - make connexons (pores that can be open or closed)

16

Name the 2 areas of the basement membrane

Basal lamina (directly below epithelial cells); reticular lamina below basal lamina

17

Name the 2 anchoring junctions on the basal surface

Hemidesmosome and focal adhesions

18

Describe focal adhesions on the basal surface

anchor the cell's internal actin to basal lamina; use integrins (transmembrane proteins) to detect/transduce signals

19

Transitional epithelium has what special cells on the apical surface

dome cells (or umbrella cells)

20

Simple squamous function

thin barrier for exchange, frictionless movement of fluids and/or organs

21

Simple cuboidal function

line a conduit, can absorb and/or secrete materials

22

Simple columnar function

absorption and/or secretion

23

Stratified squamous keratinized function

protection of dry areas

24

Stratified squamous nonkeratinized function

protection of moist areas

25

Stratified columnar function

barrier, conduit

26

Pseudostratified columnar function

secretion, conduit in resp. tract and epididymis; move mucus, absorption,

27

Transitional function

barrier in chambers and tubes that distend