Epithelium Flashcards

1
Q

What is the difference between Parenchyma and Stroma?

A

The parenchyma contains cells responsible for the function attributed to an organ. The stroma consists of cells that have a supporting role in maintenance of the structure (and thus, function) of an organ. Stroma is always connective tissue. Parenchyma and stroma interact on a basic biological level.

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2
Q

Is epithelium classified as parenchyma or stroma?

A

Parenchyma

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3
Q

What is the stroma that underlies the epithelium of the respiratory, digestive, and urinary systems called?

A

Lamina Propria

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4
Q

What does the basement membrane regulate?

A

-Cell adhesion -Cell polarity -Cell differentiaion -Barrier function of the epithelial layer

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5
Q

What are the two layers of the basement membrane?

A

-Basal Lamina (epithelium) -Reticular Lamina (stroma)

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6
Q

What are junctional complexes used for?

A

-Cell-cell adhesion -adhesion to the basal lamina -communication

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7
Q

What is the purpose of tight/occluding junctions?

A

to form seals between adjacent cells

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8
Q

What is the purpose of Adherent/anchoring junctions?

A

-to permit cells to adhere to one another to resist abrasion -To permit cells to anchor to the basal lamina

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9
Q

What is the purpose of Gap Junctions?

A

-channels to provide communication between neighboring cells

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10
Q

What is the fancy word for tight junctions?

A

Zonulae Occludens

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11
Q

What two transmembrane proteins interact to form tight junctions?

A

-claudin -occludin

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12
Q

What is the fancy word for Adherent junctions which form a belt-like adhesion?

A

Zonula Adherens

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13
Q

What is the fancy name for adherent junctions that form a spot weld-like adhesion?

A

Maculae Adherens

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14
Q

Where is the Zonula Adherens located in relation to the Zonulae Occludens?

A

It is located just below the Zonulae Occludens

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15
Q

What proteins mediate the anchoring of cells together via the zona adherens?

A

-Cadherins -Catenin

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16
Q

What proteins mediate the anchoring of cells together via the Maculae Adherens?

A

-Desmoglein and Desmocollin (Cadherins) -Anchor to Plakoglobin and Desmoplakin

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17
Q

What do hemidesmosomes do?

A

lock down an epithelial cell to the basal lamina of the basement membrane

18
Q

What do hemidesmosomes bind to in the basal membrane?

A

-laminin -Type IV collagen

19
Q

Functions of microtubules:

A

-a component of the mitotic apparatus -important for cilia and flagella functions -important for intracellular transport of vesicles and organelles

20
Q

Functions of Microfilaments:

A

-Cellular movement -cell contractile activity -movement of vesicles (cytoplasmic streaming)

21
Q

Functions of Intermediate Filaments:

A

-More stable and intermediate in size -important for differentiated cell function and shape

22
Q

What structure directs the polymerization of microtubules?

A

Microtubule Organizing Centers (MTOCs) =Centrosomes

23
Q

Brush Border

A

Microvilli on gut epithelial cells

24
Q

What microfilament is contained in microvilli?

A

Actin

25
Q

Where are stereocilia observed?

A

The absorptive cells of The epididymis and ductus deferens-Sensory hair cells

26
Q

What is the microtubule arrangement in cilia?

A

-9:2-9 microtubule doublets and two central microtubules

27
Q

What is the 9+2 microtubule arrangement in cilia called?

A

an axoneme

28
Q

What lies at the base of cilia?What structure is it similar to?

A

-Basal body -Centriole

29
Q

What is stratified epithelium?

A

epithelium that has two or more layers of cells

30
Q

What is simple epithelium?

A

epithelium that has only one layer of cells

31
Q

What kind of cells are in thin epithelium?

A

squamous

32
Q

What kind of cells are in cube shaped epithelium?

A

cuboidal

33
Q

What type of cells are in tall epithelium?

A

columnar

34
Q

Where would I find stratified squamous keratinized epithelium?

A

Skin

35
Q

What type of epithelium permits expansion of the surface?What feature allows for this expansion?

A

-Transitional Epithelium -The presence of umbrella cells, which can stretch or distend

36
Q

What is the defining feature of Pseudostratified epithelium?Where would I find it?

A

-Tall and irregular cells which are all attached to The basement membrane. Nuclei are at different levels .-The lining of The upper respiratory tract

37
Q

What is a Merocrine gland?

A

A gland that releases product via exocytosis from membrane bound vesicles

38
Q

What is a Holocrine gland?

A

A gland that releases product when cells disrupt and lyse

39
Q

What is an Apocrine gland?

A

A gland in which the apical end of the cell partitions off and is extruded into the duct, releasing products

40
Q

What is an example of a holocrine gland?

A

Sebaceous glands

41
Q

What is an example of an apocrine gland?

A

Mammary gland

42
Q

What tissue performs merocrine secretion?

A

Pancreas Acinar Cells