Epithelium Flashcards
Characteristics to classify epithleium
- number of layers
- cell shape’-presence of specializations
simple epithelium
squamous
cuboidal
columnar
stratified
squamous nonkeratinized
cuboidal
columnar
keratinized
psuedostratified
columnar
transitional
transitional relaxed
transitional distended
simple squamous
function-blood brain barrier, filtration, exchange
simple cuboidal
locations-thyroid, renal tubules, ducts of glands
functions-absorption, secretion, barrier, conduit
simple columnar non cilated
locations-stomach, intestine
functions- absorption, secretion, barrier
simple columnar ciliated
locations-uterine tubes
functions- absorption, secretion, barrier
pseudostratified columnar ciliated
locations-trachea, bronchi, ducts of male reprod sys
functions- secretion, absorption, barrier, transport
stratified squamous nonkeratinized
locations-esophagus, distal anal canal, vagina
functions- barrier, protection
stratified squamous keratinized
locations-epidermis
function-barrier, protection
transitional urothelium
locations-ureter, urinary bladder, urethra
functions-barrier, protection, distension
primary monocilium nonmotile
chemosensors, osmoreceptors, mechanoreceptors, mediate light, taste, sound perception, pivitol role in normal tissue morphogenesis
general blueprint for junctional complex
cytoskeletal elements
Intracellular anchor proteins
CAMs [transmembrane adhesion proteins]
zonula occludens
Gene encoding for a specific claudin in renal
epithelial cells results in excessive loss of
magnesium ions in urine.
Brain cancers – loss of claudin 5
Deafness – loss of claudin 9
heliobacter pylori
disrupts tight junctions causing a breach in the eputhelial lining of the stomach, causes internalization of occludins
degree of permeability
dictated by mixture of claudins to occludins
functional polarity
established by tight junctions
pemphigus
due to autoantibodies against desmogleins
bullous penphigoid
autoantibodies develop against type XVII collagen
integrin represents
a cell adhesion molecule [link protein]
problems with nexus/gap junctions
female infertility neuropathy deafness congenital cataracts cardiac arrhythmias
