epithelium and renal

Question 1

tight junctions-

Answer 1

connect plasma membrane of two adjacent cells- they do not connect the cytosol of these cells
selective barrier with varying permeability

Question 2

Apical membrane faces the____ side
it contains ____ on its surface
____ contain Na/K ATPase

Answer 2

faces luminal side
contains microvilli on its surface
doesnt contain Na/K ATPase

Question 3

what are the three driving forces for the solute/ion movement across epithelia?

Answer 3

chemical
electrical
osmotic

Question 4

function of desmosomes in epithelia?

Answer 4

hold two cells together
theyre an anchor point for intermediate filaments
important for maintaining physical structure of the epithelium so it doesnt collapse

Question 5

how does the permability of water compare in the apical vs the basolateral membrane?

Answer 5

apical has variable water permeability
basolateral has a consistent water and potassium permeability

Question 6

what is absorption and what is it driven by

Answer 6

movement from apical (mucosal) side to basolateral (serosal) side- driven by sodium transport

Question 7

what is secretion and what is it driven by?

Answer 7

movement from serosal to muscosal side
secretion driven by the Cl- transport

Question 8

true or false
hormonal control impacts leaky epithelia

Answer 8

false- no hormonal control in leaky epithelia
bulk reabsorption

Question 9

in the nephron where does bulk reabsorption occur?

Answer 9

in the proximal tubule due to its leaky epithelia

Question 10

where does fine regulation occur in the nephron?

Answer 10

distal tubule and collecting duct
under hormonal control so for the fine tuning of what the body requires