Erythema

Question 1

eruthema palmare kr lerisstent palmar erythema js usually most marked on the __ area

Answer 1

hypethenar area and is assoc w elev lebel of estrogen

Question 2

In Erythema toxicum neonatorum, when the rash is atypical, smears of pustules demonstrating what is adequate to confirm dx.

Answer 2

Eosinophils.

Question 3

is a recurrent self limited disease usually kf young adults, occ in spring and fall. each episode lasting 1-4 weeks.
lesions behin as sharply marginated, erythematous macules which become raised edematous papules over 24-48 hours. may reach several cm in diameter. a ring of erythema forms around the periphery and centrally the lesions become flatter and more pruritic and dusky. “target or iris” lesion.

Answer 3

HAEM ( erythema multiforme minor)

Question 4

Three zones if HAEM OR Herpes simplex associated EM.

Answer 4

Three zones3 central dusky purpura, elevated edematous pale ring, surrounding macular erythema.
central area may be bullous.

lesions appear symmetrically and acrally.
palms and soles.

Question 5

erythema multiforme major manif.

Answer 5

Freq accompanied w febrile prodome and sometimes arthralgua. all ages.
centered on the extremities and face. but more often than em minor may include truncal lesions wc are papular and erythematous to dusky in color.
mucous membrane diaease is prominent and iften severly involved mucosa and lips w hemorrhagic sloughing.

Question 6

Etiologic factors.

Em major and minor are assoc w what infections?

Answer 6

EM minor- HSV infection

Major- Mycoplasma infection.

Question 7

Histo EM:

Answer 7

All lesions characterized by cellular necrosis.
Activated T lymphocytes present in lesions of EM. W cytototic or suppressor cells more in epidermis. and Helper T cells in dermis.

Question 8

tx w EM.

Answer 8

EM minor- Viral.
valacyclovir 500 mg to 1 g/day,
famciclovir. prevent recurrence in upto 90% of HSV related cases.

symptoms related to oras lesions often respond to “swish and spit” mixtures containing lidocaine, diphenhydramine (benadryl) and kaolin.

Question 9

Tx for oral erythema multiforme

Answer 9

Topical steroid may be helpful )fluocinonide gel 0.05%)

swish and spit cont lidocaine, diphen, kaolin. for symptomatic relief a

Question 10

the most common gyrate erythema

Answer 10

Erythema annulare centrifugum.

Question 11

EAC us characterized by

Answer 11

Asymptomatic annular or polycyclic lesions that grow slowly (2-3mm) /day) rarely reaching more than 10 cm in diameter. trailing scale at inner border of annular erythema. surface is devoid of crusts or vesicles.
usually occur on the trunk and proximal extremities.

Question 12

EAC HISTO.

Answer 12

EAC- SP
spongiosis and parakeratosis.

Within superficial dermis and at times the deep dermis, lymphocytes are organized tightly around the blood vessels jn apattern described as “coat sleeve” areangement.

Question 13

tx EAC

Answer 13

Topical calcipotriol.

Topical steroid.

Question 14

Erythema gyrstum repens manif

Answer 14

lesions consist of undulating wavy bands of slightly elevated erythema w trailing scale over the entire body. lesions migrate rapidly upto 1 cm/ day and are concetrix “wood grain” appearance.
pruritus severe and blood eosinophilia is often found. in more than 70% of pxs; an underlying malignancy is found. Lung CA Is most commin assoc malignancy.

Question 15

EGR (erythema gyratum repens) tx

Answer 15

Resistant to tx.

cetirizine and topical steroid.

Question 16

eosinophillic annular eruthema

lesions where? gender. Histo. tx.

Answer 16

Trunk and often symmetric. 
Females. 
Histo: Dense perivascular and interstitial lymphocytic infiltrate  w eosinophils without flame figures. 
Tx: spontaneous resoution may occur. 
Hydroxychloroquine; prednisone.

Question 17

another word for eosinophilic cellulitis

Answer 17

wells syndrome