ERYTHROPOIETIN Flashcards
(25 cards)
What is erythropoietin primarily responsible for?
Stimulating red blood cell production.
What type of receptor does erythropoietin bind to?
Erythropoietin receptor (EPO-R).
True or False: Erythropoietin is produced mainly in the liver.
False, it is primarily produced in the kidneys.
Fill in the blank: Erythropoietin is a _______ hormone.
glycoprotein.
What physiological effect does erythropoietin have on the bone marrow?
It promotes the proliferation and differentiation of erythroid progenitor cells.
Multiple Choice: Which of the following conditions can erythropoietin be used to treat? A) Anemia B) Hypertension C) Diabetes
A) Anemia.
True or False: Erythropoietin has no role in the immune response.
True.
What is the primary adverse reaction associated with erythropoietin therapy?
Increased risk of thromboembolic events.
What is the mechanism of action of erythropoietin?
It activates erythropoietin receptors, leading to increased red blood cell production.
Fill in the blank: Erythropoietin can stimulate the production of _______ in the bone marrow.
erythrocytes.
What is a common clinical use of erythropoietin?
To treat anemia in patients with chronic kidney disease.
Multiple Choice: Erythropoietin is primarily released in response to which condition? A) High oxygen levels B) Low oxygen levels C) Normal oxygen levels
B) Low oxygen levels.
True or False: Erythropoietin is involved in the regulation of iron metabolism.
False.
What is the effect of erythropoietin on reticulocyte count?
It increases reticulocyte count.
Fill in the blank: Erythropoietin is often administered to patients undergoing _______ treatment.
chemotherapy.
What is the role of erythropoietin in fetal development?
It supports erythropoiesis during fetal life.
Multiple Choice: Which of the following is NOT a side effect of erythropoietin? A) Hypertension B) Headache C) Hair loss
C) Hair loss.
True or False: Erythropoietin can be synthesized for therapeutic use.
True.
What is the effect of erythropoietin on hemoglobin levels?
It increases hemoglobin levels.
Fill in the blank: The erythropoietin receptor is a member of the _______ receptor family.
cytokine.
What is the half-life of erythropoietin in circulation?
Approximately 4 to 13 hours.
Multiple Choice: Erythropoietin acts on which type of cells? A) Neutrophils B) Erythroid progenitor cells C) Platelets
B) Erythroid progenitor cells.
True or False: Erythropoietin levels are inversely related to blood oxygen levels.
True.
What is the primary site of erythropoietin production in adults?
Kidneys.
