Esophageal Diseases Flashcards
(30 cards)
Achalasia MOA?
Failure of relaxation of LES due to loss of myenteric (Auerbach) plexus
What does Achalasia lead to?
progressive dysphagia to solids and liquids
Patient only has dysphagia to solids what do you think of?
obstruction—solids only
Patient only has dysphagia to solids and liquids what do you think of?
Achalasia
Achalasia increases risk for?
squamous cell carcinoma
MC 2º cause of Achalasia?
Chagas Disease
What is associated with lye ingestion?
Esophageal strictures
Dilated submucosal veins   in lower 1 ⁄3 of esophagus 2° to portal hypertension
Esophageal varices
Esophagitis is seen in 3 bugs where?
Candida: white pseudomembrane;
HSV-1: punched-out ulcers;
CMV: linear ulcers
nocturnal cough and dyspnea, adult-onset asthma?
GERD
GERD MOA?
Decrease in LES tone
Mucosal lacerations at the gastroesophageal junction due to severe vomiting?
Mallory-Weiss syndrome
Dysphagia, Iron deficiency anemia, and Esophageal webs and glossitis?
Plummer-Vinson syndrome
Plumbers” DIE
Plummer-Vinson syndrome will lead to an increased risk of?
esophageal squamous cell carcinoma
A patient with acid reflux and dysphagia that has no wrinkling hands and feet
Sclerodermal esophageal dysmotility
Sclerodermal esophageal dysmotility MOA?
Esophageal smooth muscle atrophy=>LES pressure and dysmotility
What is the problem in barrett’s esophagus
Metaplasia=>nonkeratinized stratified squamous epithelium with intestinal epithelium=> nonciliated columnar with goblet cells in distal esophagus
What is the long term problem with barrett’s esophagus?
esophageal adenocarcinoma.
Progressive dysphagia (first solids, then liquids) and weight loss?
Esophageal cancer
Most Common Esophageal cancer is America?
Adenocarcinoma
Adenocarcinoma happens more along which part of the esophagus
Distal 1/3=> ass side 1/3
Which causes cause adenocarcinoma?
Acid Reflux, Ass side, A Fat person
Which causes cause both adenocarcinoma and squamous ?
cigarette
Upper 1/3 esophagus drains to?
cervical nodes
