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Pharmacy Pre-reg > Essentials > Flashcards

Essentials Flashcards

1
Q

CYP3A4 inhibitors

A

SEV =
Azole antifungals (ketoconazole, itraconazole SEV, fluconazole MOD), Macrolides (Clarythromycin, Erythromycin), Protease inhibitors (Ritonavir, Nirmatrelvir-Ritonavir aka Paxlovid)

MOD = Amiodarone, rlCCBs, Ciprofloxacin, Cimetidine, Ciclosporin, Grapefruit juice

WEAK = Buprenorphine, Cimetidine, Omeprazole, Ranolazine, Tacrolimus, Ticagrelor, Valproic acid, Amlodipine, Azithromycin

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2
Q

CYP3A4 inducers

A

SEV = Rifampicin, Phenytoin, Carbamazepine

MOD = St. John’s Wort, Glucocorticoids, Topiramate, Primidone, Barbiturates, Clobazam

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3
Q

CYP3A4 substrates

A

Sensitive = Statins, Losartan, CCBs (rlCCBs, Amlodipine, Felodipine, Nifedipine)

TCAs, Z-drugs, Warfarin, Amiodarone, Domperidone, Ondansetron, Propranolol, Chlorphenamine, Donepezil

Sex steroids (Finas, Estra, Ethin, Prog, Test)
BZDs (Dia, Mida, Clona)
Steroids (Dex, Hydro, Flutic, Bude)
Antidepressants (Sert, Cital, Mirtaz, Venla, Traz)
Antipsychotics (Halo, Aripip, Risp, Quet)
Opioids (Al/Fent, Bupr, Code, Methadone, Tram)

Montelukast, Salmeterol, Lidocaine, Eplerenone, Sildenafil, Tadalafil

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4
Q

Paracetamol doses

A

All q4-6h
Calpol infant 2m-6y 120mg/5mL
2-3m >4kg >37w 2.5mL (60mg)
3-6m 2.5mL (60mg)
6-24m 5mL (120mg)
2-4y 7.5mL (180mg)
4-6y 10mL (240mg)

Calpol 6+ 250mg/5mL
6-8y 5mL (250mg)
8-10y 7.5mL (375mg)
10-12y 10mL (500mg)
12-16y 10-15mL (500-750mg)
16+ 10-20mL (500-1000mg)

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5
Q

Paracetamol dose reductions

A

<50kg = 500mg max dose
Renal (<30mL/min) + IV = 1g q6h
Hepatic = 1g TDS (500mg TDS I’d also <50kg)

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6
Q

How much stronger is sublingual fentanyl than oral morphine

A

PO Morphine 10mg : SL Fentanyl 100mcg

100 X Stronger

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7
Q

Dose conversion between PO Morpine and SC/IV

A

PO Morphine 10mg : SC/IV Morphine 5mg

2 X Stronger

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8
Q

Converting PO Morphine to Codeine / Dihydrocodeine / Tramadol

A

PO Morphine 10mg : 100mg of each

10 X Stronger

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9
Q

Morphine to Codeine / Dihydrocodeine / Tramadol

A

PO Morphine 10mg : 100mg of each

10 X Stronger

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10
Q

Morphine to Oxycodone

A

PO Morphine 10mg : PO Oxycodone 6.6mg

1.5 X Stronger

To SC/IV Oxycodone 5mg so 2 X Stronger

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11
Q

Safest opioid in pregnancy and breastfeeding

A

Dihydrocodeine

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12
Q

Opioid affecting seizures

A

Tramadol

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13
Q

Ibuprofen dosing

A

100mg/5mL
1-2m 5mg/kg TDS-QDS
3-5m 2.5mL (50mg) >5kg TDS only use for 24h
6-12m 2.5mL (50mg) TDS-QDS only use for 72h
1-3y 5mL (100mg) TDS
4-6y 7.5mL (150mg)
7-9y 10mL (200mg)
10-11y 15mL (300mg)
12+ 15-20mL (300-400mg) TDS-QDS

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14
Q

Drugs that make your urine blue or green

A

Amitriptyline
Cimetidine
Indometacin
Promethazine

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15
Q

Drugs that turn your urine brown

A

Metronidazole
Nitrofurantoin
Phenytoin

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16
Q

Drugs that turn your urine orange

A

Rifampicin
Sulfasalazine

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17
Q

Drugs that turn your urine pink

A

Doxorubicin
Daunorubicin
Nefopam
Phenytoin

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18
Q

Drugs that turn your urine yellow

A

Nitrofurantoin
Senna
Sulfasalazine
Tolcapone
Vitamin B

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19
Q

Drugs that turn your urine red

A

Co-danthramer
Chlorpromazine
Doxorubicin
Daunorubicin
Entacapone
Levodopa
Rifampicin
Rifaximin
Senna

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20
Q

Adrenaline dosing in anaphylaxis

A

<6m 100-150mcg
6m-5y 150mcg
6-11y 300mcg
12-17y 500mcg (300mcg if pre-puberty)
Adult 500mcg

Into the upper thigh

Repeat dose 5mins later, call 999 after 10mins and keep giving doses until requirement met

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21
Q

Ultra rapid insulins

A

Fiasp (Aspart) flextouch
Lyumjev (Lispro) Kwikpen

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22
Q

Rapid acting insulins

A

Novorapid (Aspart) flexpen
Humalog (Lispro) Kwikpen 100/200
Apidra (Glulisine) solostar

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23
Q

Short acting insulin

A

Soluble human insulins:
Actrapid flex pen/ vial
Humulin S vial

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24
Q

Intermediate acting insulin

A

Isophane insulins:
Innolet (Insulatard)
Humulin I Kwikpen

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25
Q

Long acting insulins

A

Levemir (Detemir) flexpen
Lantus (Glargine) solostar
Abasaglar (Glargine) kwikpen
Tresiba (Degludec) flextouch 100/200
Toujeo (Glargine) solostar 300

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26
Q

Biphasic insulins

A

Novomix 30 (isophane 30/aspart 70) Flexpen
Humalog mix 25 (lispro 25/ protamine lispro 75) Kwikpen
Humalog mix 50 (lispro 50/ protamine lispro 50) Kwikpen

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27
Q

Opioids reversal agent

A

Naloxone

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28
Q

Benzodiazepines reversal agent

A

Flumenazil

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29
Q

Heparin reversal agent

A

Protamine sulfate

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30
Q

Aspirin reversal agent

A

Platelet concentrate infusion
Or desmopressin

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31
Q

Warfarin reversal agent

A

Vitamin k aka phytomenadione

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32
Q

DOACs reversal agent

A

Adexanet alfa for Apixaban Edoxaban and Rivaroxaban
Idarucizumab for Dabigatran

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33
Q

Paracetamol reversal agent

A

N-Acetylcysteine

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34
Q

N-Acetylcysteine dosing for paracetamol overdose

A

150mg/kg 1h then 50mg/kg 4h then 100mg/kg 16h

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35
Q

What is the licensed minimum age for Pseudoephedrine

A

12+

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36
Q

What is the licensed minimum age for Guaifenisin

A

2+

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37
Q

What is the licensed minimum age for
Benzocaine ear drops

A

2+

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38
Q

What is the licensed minimum age for Otrivine (Xylometolazine) for nasal congestion

A

6+

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39
Q

What is the licensed minimum age for sodium bicarbonate ear drops for ear wax

A

5+

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40
Q

What is the licensed minimum age for sodium cromoglicate eye drops for allergic conjunctivitis

A

2+

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41
Q

What is the licensed minimum age for carbomer eye gel for dry eyes

A

2+

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42
Q

What is the licensed minimum age for Anbesol and EMLA formulations of Lidocaine

A

Anbesol 5months +
EMLA 3months +

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43
Q

What is the licensed minimum age for bonjela

A

16+

choline salicylate

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44
Q

What is the licensed minimum age for aciclovir aka zovirax

A

All ages

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45
Q

What is the licensed minimum age for gaviscon adult

A

12+

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46
Q

What is the licensed minimum age for peptac

A

6+

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47
Q

What is the licensed minimum age for stimulant laxatives

A

12+

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48
Q

What is the maximum pack size of stimulant laxatives OTC

A

20

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49
Q

What is the licensed minimum age for peppermint oil

A

15+

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50
Q

What is the licensed minimum age for mebeverine

A

18+

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51
Q

What is the licensed minimum age for canesten and what drugs can be in canesten

A

16+
Fluconazole or clotrimazole

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52
Q

What is the licensed minimum age for daktarin and daktarin gold

A

Daktarin contains miconazole all ages
Daktarin gold is Ketoconazole 18+

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53
Q

What advice would you give OTC regarding steroid creams

A

Don’t use on face

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54
Q

What warning comes with emollients

A

Flammable

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55
Q

What is the licensed minimum age for hydrocortisone cream and ointment otc

A

Ointment is POM
Cream 10+
Dermacort

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56
Q

What is the licensed minimum age for eumovate cream

A

Clobetasone 12+

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57
Q

What is the licensed minimum age for mepyramine

A

Anthisan bite and sting 2+

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58
Q

What is the licensed minimum age for benzoyl peroxide

A

Acnecide 12+

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59
Q

What strength of ibuprofen gel is available otc and at what age

A

5% 12+ P med
10% POM

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60
Q

What is the licensed minimum age for hyoscine hydro bromide

A

Kwells 4+

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61
Q

What is the licensed minimum age for loperamide otc

A

Imodium 12+

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62
Q

What is the licensed minimum age for germaloids

A

12+
Zinc oxide and lidocaine

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63
Q

What is the licensed minimum age for anusol and HC

A

18+
Zinc oxide, bismuth oxide, balsam peru
HC also contains hydrocortisone and benzyl benzoate

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64
Q

What is the difference between the different benylins

A

Benylin (Diphenhydramine + Levomenthol) 6+
Benylin infant (glycerol) 3months+
Benylin chesty cough (Guaifenasin) 6+
Benylin dry cough and sore throat (Glycerol + Sucrose) 1+
Benylin dry cough (Dextromethorphan) 12+

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65
Q

What is the licensed minimum age for Solpadeine plus and max

A

Solpadeine plus (Paracetamol, Codeine, Caffeine) 12+
Solpadeine max (Paracetamol, Codeine) 12+

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66
Q

What is the licensed minimum age for nurofen

A

Ibuprofen 3months+

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67
Q

What is the licensed minimum age for stugeron

A

Cinnarazine 5+

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68
Q

What is the licensed minimum age for avomine

A

Promethazine 5+

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69
Q

What is the licensed minimum age for migraleve

A

12+
Paracetamol, Codeine, Buclizine

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70
Q

What is the licensed minimum age for Beconase nasal spray

A

18+
Beclometasone

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71
Q

What is the licensed minimum age for piriton

A

Chlorphenamine 1+

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72
Q

What is the licensed minimum age for piriteze

A

Cetirizine 6+

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73
Q

What is the licensed minimum age for clarityn

A

Loratadine 2+

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74
Q

What is the licensed minimum age for Sudafed

A

Pseudoephedrine 12+

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75
Q

Max Sudafed purchase otc

A

720mg

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76
Q

What is the licensed minimum age for difflam rinse, spray and lozenge

A

Benzydamine
12+ rise
6+ spray
6+ lozenge

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77
Q

What is the licensed minimum age for lemsip

A

Paracetamol, caffeine, phenylephrine
16+

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78
Q

What is the licensed minimum age for night nurse

A

Paracetamol, promethazine, dextromethorphan

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79
Q

What is carbocysteine contraindicated in

A

Active peptic ulceration

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80
Q

What laxative should be avoided in IBS

A

Lactulose as it causes bloating

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81
Q

What must be administered with isoniazid and why

A

Pyridixine B vitamin to reduce peripheral neuropathy

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82
Q

Which antibiotic requires visual function monitoring if treatment will last longer than 28 days

A

Linezolid can cause severe optic neuropathy

83
Q

Docusate max dose

A

500mg daily in divided doses
Low dose is 100mg BD
High dose is 200mg BD
Never seen more than 400mg given

84
Q

What laxative colours the urine pink

A

Co-danthramer

85
Q

What Parkinson’s medicine can colour the urine a reddish-brown

A

Entacapone

Levodopa is just red not brown

86
Q

Treatment with what drug can delay the need for Levodopa in parkinson’s

A

Selegiline

87
Q

What Parkinson’s med is cautioned in heart failure and why

A

Amantadine exacerbates oedema

88
Q

What Parkinson’s med can cause alopecia

A

Selegiline

89
Q

Fat soluble vitamins

A

ADEK

90
Q

Drugs that can cause Neutropenia

A

Aminosalicylates, phenothiazines, clozapine, valproate, carbamazepine, Ethosuximide, phenytoin, atovaquone, cefalosporins, chloramphenicol, chloroquine, ciprofloxacin, metronidazole, Sulfasalazine, carbimazole, ibuprofen, allopurinol, colchicine, methotrexate, penicillins

91
Q

Drugs that damage the lungs

A

Amiodarone, ACEi, beta blockers, protamine, ergot D2 agonists, NSAIDs, methotrexate, nitrofurantoin, infliximab

92
Q

Drugs that cause C.diff

A

Clindamycin, Ciprofloxacin, Co-amoxiclav, Cefalosporins, PPIs

93
Q

Max dose of loperamide

A

16mg in 2 divided doses

High output stoma can be 16mg BD

94
Q

Max dose lorazepam

A

2mg/24h

95
Q

What are the risks associated with potassium permanganate tablets

A

For dilution then external use only in the treatment of cleansing eczematous wounds and reactions

Risk of fatal ingestion

96
Q

What schedule is midazolam

A

3

97
Q

What schedule is temazepam

A

3

98
Q

What schedule is buprenorphine

A

3

99
Q

What schedule is secobarbital

A

2

100
Q

What schedule is phenobarbital

A

3

101
Q

What schedule is primidone

A

3

102
Q

Counselling point for latanoprost

A

Can change eye colour and reduce orbital fat making eyes look sunken in

103
Q

Vitamin D deficiency symptoms

A

Thick painful joints
Bowed legs
Soft weak bones

104
Q

What are the two stages of scalp psoriasis topical treatments

A

1st coal tar shampoo (T-gel, Caporsal, Alphosyl)
2nd Ketoconazole shampoo (Nizoral)

105
Q

Which antihistamine has multiple daily dosing

A

Acrivastine

106
Q

Carbocysteine contraindications

A

Active peptic ulcer disease

107
Q

Carbocysteine contraindications

A

Active peptic ulcer disease

108
Q

What does an inspiratory wheeze indicate

A

Bronchospasm
SABA / LABA

109
Q

What does an expiratory wheeze indicate

A

Secretions/ mucous
Saline nebules/ carbocysteine/ acetylcysteine

110
Q

What vaccine would a patient with Asplenia get

A

Pneumococcal

111
Q

Food poisoning symptoms

A

Vomit, diarrhoea, malaise, intermittent recurrent GI irritation or pain

112
Q

Cystitis symptoms

A

Painful urination (burning/stinging) aka Dysuria
Frequent urination polyuria for frequency not amount
Small amounts of urine aka oliguria
Dark urine
Smelly urine

113
Q

What non-drugs does warfarin interact with

A

Green leafy vegetables that contain vitamin K, this includes green tea, not mint tea
Cranberry
Grapefruit
Garlic
Alcohol
Black licorice
Ginger
Ginkgo biloba
St. John’s wort
Turmeric
Omega 3 supplements

114
Q

What dose would warrant slower steroid withdrawal

A

Equivalent or more than 40 mg prednisolone for longer than 1 week

115
Q

Methotrexate supply restrictions

A

Only 2.5mg tablets
Dose and frequency must be on dispensing label and counselled to the patient
Extra meds like folic acid and patient counselling on them
No MDU
Counsel patient on blood disorders (sore throat, bruising, mouth ulcers), liver toxicity (N&V, Abdo discomfort, dark urine), respiratory effects (SoB)

116
Q

Which antidepressants can lower the seizure threshold

A

SSRIs, TCAs, MAOi

117
Q

Patient has bleeding gums what action to take

A

Do they take Amlodipine or Phenytoin known to cause gingivinal hyperplasia

If not recommend flossing to reduce bleeding

118
Q

Drugs unsafe in Porphyria

A

Anabolics, Antidepressants, Barbiturates, Contraceptives, HRT, azole antifungals, NNRTIs and Protease inhibitor HIV treatments, Progestogens, Sulfonylureas, Taxanes, AEPs apart from gabas and L drugs, All non-cef UTI treatments, rlCCBs

Alcohol, Amiodarone, Artemether with lumefantrine, Chloramphenicol, Clindamycin, Erythromycin, Indapamide, Oxybutynjn, Risperidone, Spironolactone, Tamoxifen

119
Q

Drugs that can cause lupus

A

Isoniazid, Hydralazine, Infliximab, Adalimumab, Etanercept, Quinidine, AEPs, Chlorpromazine, Methyldopa, Sulfasalazine,

120
Q

Drugs that can induce migraines

A

Contraceptives
Heart medications
NSAIDs
Paracetamol
Analgesia
Caffeine
Triptans
Sleep aids

121
Q

What does a cobalt allergy contraindicate

A

Vitamin B12 formulations made with it

122
Q

What age are erectile dysfunction medications licensed in

A

All ages

123
Q

Hypothyroidism symptoms

A

Fatigue, weight gain, constipation, menstrual irregularities, depression, dry skin, cold intolerance, widespread hair loss

124
Q

Hyperthyroidism symptoms

A

Sweating, Goitre, hyperactivity, sleep disturbance, fatigue, palpitations, anxiety, heat intolerance, increased appetite, unintentional weight loss, diarrhoea

125
Q

Naproxen otc age range

A

15-50

126
Q

Colchicine interactions

A

If taking a CYP3A4 inhibitor 1/2 colchicine dose

127
Q

From what age can threadworm be treated otc

A

2y

128
Q

Which inhalers have extra fine particles

A

Some Beclometasone pMDI inhalers
Qvar, Kelhale
Combined Beclometasone and formoterol
Luforbec, Fostair

129
Q

Which inhalers are good for the environment

A

DPIs (turbohaler, accuhaler, breezhaler, easyhaler, ellipta, genuair, handihaler, NEXThaler, spiromax)

Soft mist inhalers (Spiriva respimat)

Breath actuated (autohaler, easibreathe)

130
Q

Lidocaine for teething otc age

A

5-6m brand dependent

131
Q

Teething treatment pathway

A

1st self care (rub gum with clean finger, bite cool object, cuddle, reassure, remove excess saliva to avoid infection and rash)
2nd OTC paracetamol/ ibuprofen
3rd lidocaine if 6m+

132
Q

What does Hutchinson’s sign indicate

A

Shingles

133
Q

Can NSAIDs be used in preganancy

A

Avoid from week 20

134
Q

Can benzydamine (Corsodyl) be used in pregame y

A

Avoid throughout

135
Q

Drugs that cause Steven johnson syndrome

A

AEPs (category 1 and Lamotrigine)
AntiPsych (Haloperidol, Quetiapine, Risperidone)
Abx (Penicillins, Cefs, Quinn’s, Aminoglycosides)
Allopurinol
Sulfonamides (Sulfasalazine, Co-trimoxazole)
Paracetamol
NSAIDs
Contrast media

136
Q

Differentials between Scarlet fever, chickenpox, oral thrush, hand foot and mouth disease, shingles, HSV

A

Chickenpox rash is disseminated (widespread) and itchy

Shingles is unilateral and confined to a dermatome aka along a nerve in a line from spine

Hand foot and mouth is only located here with low fever and oral lesions
Oral thrush can be scraped off and covers tongue like a rug

Scarlet fever is usually patches or a strawberry tongue with sandpaper disseminated rash and fever and flushing

HSV confined to small patch +/- fever

137
Q

Licensed age for chloramphenicol otc

A

2y+

138
Q

What should be monitoried with pseudoephedrine

A

CI <6y
CI if uncontrolled HTN, SEV Renal disease
Can cause PRES, RCVS, SJS, MI
Seek attention if SEV headache, N&V, Confusion, Seizures, Vision

139
Q

Chlorphenamine age range

A

6y+

140
Q

Medicine licensed for PCOS and Diabetes

A

Metformin

141
Q

Which chemotherapy not myelosuppressive

A

Vinka alkaloids

142
Q

Which chemotherapy worst for N&V

A

Cisplatin

143
Q

BMI ranges

A

Underweight <18.5
Healthy 18.5-24.9
Overweight 25-29.9
Obese 30-39.9
Morbidly obese >40

144
Q

What conditions does the NMS cover

A

Asthma, COPD
T2DM
HTN, High cholesterol, HF, ACS, AF, VTE, Stroke/TIA, Coronary heart disease
OP, Gout
Glaucoma
Epilepsy, PD
Urinary incontinence/ retention

145
Q

Hypothyroid bloods

A

High TSH
Low T3/4

146
Q

Hyperglycaemia symptoms

A

Excess urine polyuria
Excess thirst polydipsia
Unexplained weight loss
Excess Fatigue
Blurred vision
Nausea
Headache
Regular genital thrush infections due to glucose in urine

147
Q

Hypoglycaemia symptoms

A

Excess hunger
Clamminess
Shaking
Sweating
Confusion
Coma

Nocturnal hypoglycaemia warrants dose adjustments
Sleep disturbance
Night sweats
Fatigue in morning

148
Q

What supplements should be avoided in pregnancy

A

Cod liver oil has A in
Vitamin A - Retinol teratogenic

149
Q

Patient takes methotrexate how long before conception, how long stay on contraception

A

6m

150
Q

What electrolytes does bendroflumethiazide affect

A

Hypocalcaemia
Hyponatraemia
Hypokakaelmia

151
Q

Long term risks of PPIs

A

C.diff
Fractures
Hypomagnesaemia
CAP

152
Q

Which PPI GSL

A

Esomeorazole 20mg GR tabs as Nexium Control
Omeprazole 10-20mg GR caps

153
Q

Paracetamol dose for a 4 month old child

A

2.5mL QDS of 120mg/5mL

154
Q

Paracetamol dose for an 18 month old child

A

5mL QDS of 120mg/5mL

155
Q

Paracetamol dose for a 1 year old child

A

5mL QDS of 120mg/5mL

156
Q

Paracetamol dose for a 3.5y old child

A

7.5mL QDS of 120mg/5mL

157
Q

Paracetamol dose for a child that turns 4 in a week

A

7.5mL QDS of 120mg/5mL

158
Q

Paracetamol dose for a 4 year old child

A

10mL QDS of 120mg/5mL

159
Q

Paracetamol dose for a 5 year old child

A

10mL QDS of 120mg/5mL

160
Q

Paracetamol dose for a 6 year old child

A

5mL QDS of 250mg/5mL

161
Q

Paracetamol dose for an 8 year old child

A

7.5mL QDS of 250mg/5mL

162
Q

Paracetamol dose for a 9 year old child

A

7.5mL QDS of 250mg/5mL

163
Q

Paracetamol dose for a 10 year old child

A

10mL QDS of 250mg/5mL

164
Q

Paracetamol dose for a 12 year old child

A

10-15mL QDS of 250mg/5mL

165
Q

Paracetamol dose for a 13 year old child

A

10-15mL QDS of 250mg/5mL

166
Q

Paracetamol dose for a 14 year old child

A

10-15mL QDS of 250mg/5mL

167
Q

Paracetamol dose for a 15 year old child that weighs 38kg

A

10mL QDS of 250mg/5mL

168
Q

Paracetamol dose for a 15 year old child that weighs 50kg

A

10-15mL QDS of 250mg/5mL

169
Q

Paracetamol dose for a 15 year old child that weighs 42kg

A

10-15mL QDS of 250mg/5mL

170
Q

Paracetamol dose for a 16 year old child

A

10-20mL QDS of 250mg/5mL

171
Q

Paracetamol dose for a 16 year old child that weighs 39kg

A

10mL QDS of 250mg/5mL

172
Q

Paracetamol dose for a 17 year old child

A

10-20mL QDS of 250mg/5mL

173
Q

Paracetamol dose for an 18 year old

A

10-20mL QDS of 250mg/5mL

174
Q

Paracetamol dose for a 19 year old that weighs 38kg

A

10mL QDS of 250mg/5mL

175
Q

Paracetamol dose for a 17 year old that weighs 50kg with a renal function of 22mL/min

A

10-20mL q6h of 250mg/5mL

176
Q

Ibuprofen dose for a 12 week old child weighing 6kg

A

2.5mL TDS of 100mg/5mL for max 24h

177
Q

Ibuprofen dose for a 26 week old child

A

2.5mL TDS-QDS of 100mg/5mL for max 72h

178
Q

Ibuprofen dose for a 50 week old child

A

2.5mL TDS-QDS of 100mg/5mL for max 72h

179
Q

Ibuprofen dose for a 9 month old child

A

2.5mL TDS-QDS of 100mg/5mL for max 72h

180
Q

Ibuprofen dose for a 1 year old child

A

5mL TDS of 100mg/5mL

181
Q

Ibuprofen dose for a 52 week old child

A

5mL TDS of 100mg/5mL

182
Q

Ibuprofen dose for an 18 month old child

A

5mL TDS of 100mg/5mL

183
Q

Ibuprofen dose for a 3.5 year old child

A

5mL TDS of 100mg/5mL

184
Q

Ibuprofen dose for a 4 year old child

A

7.5mL TDS of 100mg/5mL

185
Q

Ibuprofen dose for a 5 year old child

A

7.5mL TDS of 100mg/5mL

186
Q

Ibuprofen dose for a 6 year old child

A

7.5mL TDS of 100mg/5mL

187
Q

Ibuprofen dose for a 7 year old child

A

10mL TDS of 100mg/5mL

188
Q

Ibuprofen dose for an 8 year old child

A

10mL TDS of 100mg/5mL

189
Q

Ibuprofen dose for a 9 year old child

A

10mL TDS of 100mg/5mL

190
Q

Ibuprofen dose for a 10 year old child

A

15mL TDS of 100mg/5mL

191
Q

Ibuprofen dose for an 11.5 year old child

A

15mL TDS of 100mg/5mL

192
Q

Ibuprofen dose for a 12 year old child

A

15-20mL TDS-QDS of 100mg/5mL

193
Q

Ibuprofen dose for a 14 year old child

A

15-20mL TDS-QDS of 100mg/5mL

194
Q

Ibuprofen dose for a 13 year old that weighs 35kg

A

15-20mL TDS-QDS of 100mg/5mL

195
Q

Ibuprofen dose for a 15 year old

A

15-20mL TDS-QDS of 100mg/5mL

196
Q

Ibuprofen dose for a 16 year old

A

15-20mL TDS-QDS of 100mg/5mL

197
Q

A patient with AF and a mechanical valve taking Warfarin with a target INR of 3-4 has their INR checked in clinic it’s 5.5 what do you do

A

Hold 1-2 doses of warfarin and reduce the patients maintenance dose

198
Q

A patient with AF and a mechanical valve taking Warfarin with a target INR of 3-4 has their INR checked in clinic it’s 7 what do you do

A

Hold 1-2 doses of Warfarin and reduce their maintenance dose

199
Q

A patient with AF and a mechanical valve taking Warfarin with a target INR of 3-4 has their INR checked in clinic it’s 4.5 what do you do

A

Reduce maintenance dose and recheck INR

200
Q

A patient with AF and a mechanical valve taking Warfarin with a target INR of 3-4 has their INR checked in clinic it’s 10 what do you do

A

Stop warfarin
Give vitamin K IV preparation Orally off label and repeat vitamin K if INR still high in 24h
Restart warfarin when INR <5

201
Q

A patient with AF and a mechanical valve taking Warfarin with a target INR of 3-4 presents to hospital with heartburn and coffee ground vomit. They have their INR checked it’s 8 what do you do

A

Stop warfarin
Give IV Vit K, repeat dose in 24h if INR still high
Restart warfarin when INR <5

202
Q

A patient with AF and a mechanical valve taking Warfarin with a target INR of 3-4 presents to hospital with heartburn and coffee ground vomit. They have their INR checked it’s 6 what do you do

A

Stop warfarin
Give IV Vit K STAT
Restart warfarin when INR <5

203
Q

Warfarin loading regimen

A

10mg OD 2d or 5mg BD 2d
5mg OD if frail, old, low weight, liver impairment, cardiac failure, high bleed risk
AF 1-2mg OD starting slow loading over 3-4w

Once 2 INR in range 24h apart maintenance dose is 3-9mg unless AF

204
Q

Drugs that cause Steven Johnson syndrome

A

Allopurinol in high doses
Antipsychotics - halo, quet, risp
Carbamazepine
Lamotrigine
Oxicam NSAIDs
Barbiturates
Sulfasalazine
Co- Trimoxazole
Paracetamol
Penicillins, Cefs, Quins, Aminoglycosides

Pharmacy Pre-reg (5 decks)

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