ETC-Ox Phos Flashcards
(10 cards)
ATP synthase
uses H+ gradient (chemiosmosis)
uses H+ to make ATP (3H+ for each one)
ATP synthase inhibitor
oligomyocin: blocks Fo channel
ATP synthase uncoupler
2,4 DNP (dinitrophenol)=makes heat but no ATP
pt dies of hyperthermia
Cyanide
inhibits ATP synthesis by binding Fe3+ in complex IV
Carbon monoxide poisoning
inhibts ATP synthesis by binding Fe2+, no ei flow to O2
Complex I
NADH dehydrogenase; pumps 4 H+, takes 2e from NADH to CoQ
CoQ
mobile electron carrier; from I to III
Complex III
ubiquinone-cytochomr C oxidoreductase-4H+, take Es from CoQ and loads them onto cytochrome c
Cytochrome C
mobile electron carrier that carries only one electron each to IV
Complex IV
cytochrome c oxidase pumps 2H+ and O2 is reduced to H2O