Evaluating prognosis Flashcards
1
Q
Kaplan-Meier curves
A
-used to plot time to event
2
Q
Right Censored
A
-observation was terminated before all events could be observed (missed future events)
3
Q
Left censored
A
-observations began well after some events have occurred (missed past events)
4
Q
Log-rank test
A
- comparison of survival rates of two samples
- non-parametric test
- analyses the difference between the survival curves of two groups
- cannot be used to account or adjust for effects of confounders as it is a univariate test
5
Q
Cox regression analysis
A
- multiple variables taken into account
- proportional hazard as it assumes that teh effects of multiple variables are constant over a period of time
- semi-parametric method
6
Q
Hazard ratio
A
-gives size of differences between survival curves (log rank test only informs if there is a difference)
7
Q
Mantel-Haenszel test
A
-can be used to study the effect of two binary independent variables (e.g male vs female and treatment vs placebo) on the outcome
8
Q
1 categorical independent variable=
A
Kaplan-Meier curve with log rank test
9
Q
> 1 multivariate independent variables (categorical)
A
Cox’s proportional hazard
10
Q
2 independent variables (categorical)
A
Mantel-Haenszel test
