Everything Flashcards

(58 cards)

1
Q

Presentation of Hypercalcaemia

A

STONES, BONES, GROANS, MOANS
Bone pain
Kidney stones
Constipation, nausea vomiting
Fatigue, depression, psychosis

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2
Q

Management of Hypercalcaemia

A

IV fluids

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3
Q

Presentation of Hypocalcaemia

A

CATs go numb
Convulsions
Arrythmia
Tetany and carpopedal spasm
Paraesthesia- Tingling
Muscle cramps
Seizure
Teeth deformity

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4
Q

Management of Hypocalcaemia

A

A-E
10ml IV calcium gluconate
Oral calcium + vit D

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5
Q

Causes of Hypocalcaemia

A

Low PTH
- parathyroid destruction by surgery, metastases or amyloidosis
-autoimmune

High PTH
- vit D deficiency
- PTH resistance

Hyperventilation
Acute Pancreatitis

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6
Q

Risk factors for hypocalcaemia

A

Lack of vitamin D & magnesium
IBD
CKD

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7
Q

Causes of hypercalcaemia

A

Norm/eleeaved PTH
Primary/tertiary hyperparathyroidism
Lithium induced hyperparathyroidism
Familial hypocalciuric hypercalcaemia
Low PTH
Malignancy
Vit d intoxication
Thyrotoxicosis
Adrenal insufficiency

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8
Q

What is chronic bronchitis

A

An infection of the bronchi, causing inflammation and irritation. This causes more mucus production and therefore coughing. Chronic- daily productive cough >3/12 for 2 years in a row.
1 of 2 conditions of COPD

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9
Q

risk factors for chronic bronchitis

A

Smoking
Exposure to irritants- grain dust, textiles, ammonia, strong acids.
Reduced immune system

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10
Q

risk factors for chronic bronchitis

A

Smoking
Exposure to irritants- grain dust, textiles, ammonia, strong acids.
Reduced immune system

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11
Q

What is the difference between Gastric and Duodenal ulcers

A

Gastric ulcer- pain worsened by food/eating, may have vomiting/haematemesis, melena, epigastric pain
Duodenal ulcer- pain improved by food/eating, pain few hours after eating.

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12
Q

What is erythema infectiousum

A

Parvovirus B19, slapped cheek, fifths disease

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13
Q

What is erythema infectiousum management

A

Fade over 1-2 weeks
Fluids, rest analgesia
Not infectious once they have the rash.

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14
Q

What is a fibroadenoma

A

The most common benign growth in the breast (neoplasia). They are proliferations of stromal and epithelial tissue of the duct lobules. They have a low malignant potential.
Commonly called breast mice because they move around so much.

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15
Q

presentation of fibroadenoma

A

Highly mobile lesions
Well-defined and rubbery on palpation
Often <5cm diameter
Can be multiple and bilateral
Change in size during pregnancy or premenstrual.

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16
Q

What is a pneumothorax

A

Occurs when air gets into the pleural space, separating the lung from the chest wall. It can occur spontaneously, secondary to trauma, iatrogenically or due to lung pathology. The typical patient is a tall, thin, young man presenting with sudden SOB and pleuritic chest pain when playing sport.

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17
Q

Where is the triangle of safety for a chest drain

A

The5th intercostal space(or the inferior nipple line)
Themidaxillary line(or the lateral edge of thelatissimus dorsi)
Theanterior axillary line(or the lateral edge of thepectoralis major

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18
Q

signs of a tension pneumothorax

A

Tracheal deviation
Reduced air entry on affected side
Increased resonance to precussion
Tachycardia
hypotension

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19
Q

what is strabismus

A

Also called a squint, is there the eyes point in different directions

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20
Q

causes of strabismus

A

Idiopathic
Hydrocephalus
Cerebral palsy
Space occupying lesions- retinoblastoma
trauma

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21
Q

management of strabismus

A

Refer (surgery for the muscles before the age of 7). Medial and laterus rectus for esotropia and exotropia (free lateral, tighten medial).
Corrective glasses
Occlusion therapy for lazy eye- use patch or classes part time.
penalization therapy (deliberately blur good eye using atropine drops to force child to use other eye- 2nd choice to occlusion)
Botulinum toxin – injection can cause paralysis for 3 months and correct a squint

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22
Q

What is vasovagal syncope

A

It is a benign condition caused by activation of the PNS in response to certain emotional or environmental triggers. Typically they occur after standing for a prolonged period of time, by fasting, dehydration, being in crowded or excessively warm environments or following stressful events, like seeing blood and needles. These trigger a vasovagal reaction that consists of bradycardia, vasolidation of peripheral blood vessels- hypotension, which reduces the brains oxygen supply resulting in cerebral hypoperfusion and loss of consciousness

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23
Q

what is orthostatic hypotension

A

when they drop BP when changing from lying to standing. This occurs due to a delay in constriction of the lower body veins, which is needed to maintain adequate blood pressure when changing to the standing position. When the delay occurs, it is due to blood pooling in the veins of the leg, resulting in less blood returning to the heard- causing a drop in cardiac output and blood pressure.

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24
Q

what is eisenmenger syndrome?

A

in Atrial septal defect. A complication where pulmonary pressure > systemic pressure, resulting in a right to left shunt- cyanotic

25
management of atrial septal defect
If small and asymptomatic, monitoring may be appropriate Closed through transvenous catheter closure or open heart surgery. Anticoagulants (aspirin, warfarin and NOACs- used to reduce stroke risk in ADULTS).
26
signs of atrial septal defect
SOB Difficulty feeding Poor weight gain Lower respiratory tract infections Mid-systolic, crescendo decrescendo murmur, splitting S2 sound.
27
complications of atrial septal defect
Paradoxical embolism (doesn’t go to lungs, goes through defect to brain) AF/ atrial flutter Pulmonary hypertension Eisenmenger syndrome- where pulmonary pressure > systemic pressure, resulting in a right to left shunt- cyanotic
28
what is atrial septal defect
A hole in the membrane that separates the atria. It is a congenital condition. The foramen ovale is present in fetal circulation and allows for unidirectional blood flow (which should shut and fuse at birth). Causes a left to right shunt (pressure). The pressure is higher on the left, which overloads the right with blood and if large can cause damage to the heart if left untreated.
29
risk factors for atrial septal defect
Associated with foetal alcohol syndrome More common in down syndrome children
30
what are haemorrhoids
Distended/abnormally swollen blood vessels within the anal canal. They either present above the dentate line (internal) or below (external). The line is 2cm above the anal verge. 1st degree-4th degree piles internal Do not prolapse Prolapse on straining/reduce spontaneously Prolapse on straining /reduce manually Permanently prolapsed/ cannot be reduced. External- lie under perianal skin. Have sensory innervation so may be painful, may be visible
31
risk factor for haemorrhoids
Constipation Prolonged straining Heavy lifting Increased abdo pressure, e.g. pregnancy ascites, pelvic mass Chronic cough Age Exercise
32
management of haemorrhoids
Prevent and manage constipation- increase fluids, fibre intake and laxatives Analgesia, topic anaesthetic, anusol, topical corticosteroid to reduce inflammation, Rubber band ligation, infrared coagulation, injection sclerotherapy Surgical- haemorrhoidectomy, stapled haemorrohoidectomy REFER & admit Extreme pain, external present within 72hr onset Internal haemorrhoids which have prolapsed and become swollen, thrombosed perianal sepsis Refer non urgent assessment if: 3rd or 4th degree which are too large for non operative measures Perianal haematoma if <24hrs Combined internal and external H’s with severe symptoms Thrombosed haemorrhoids when bleeding is problematic or chronic irritation/lead Large skin tags
33
What murmur would you hear for tricuspid stenosis
mid/late diastolic at the left sternal edge, heard best during inspiraiton
34
what is tricuspid stenosis
Narrowing of the tricuspid valve (right atrium to right ventricle (deoxygenated blood flow)). It commonly occurs as a late complication of acute rheumatic aortic /mitral disease
35
management of an animal bite?
Irrigate wound Consider tetanus immunization Abx prophylaxis- co-amoxiclav x5d (doxycycline + metronidazole for those with penicillin allergy) Cat, human <3 day old human bites, dog bites to face foot or genitals. Involve ortho or plastics if surgical debridement is required If human- blood tests for Hep B/C/ HIV
36
types of bowel ischaemia
Decreased blood flow to the gastrointestinal tract. It can be acute or chronic mesenteric ischaemia or colonic ischaemia. Acute mesenteric ischaemia can be divided into embolic, thrombotic and venous. Colonic is most common and has the best prognosis.
37
explain the main blood supply to the stomach
Foregut (stomach, duodenum, biliary system, liver, pancreas, spleen) – coeliac artery Midgut- distal duodenum to frist ½ transverse colon- superior mesenteric artery Hindgut- second ½ of colon to recum- inferior mesenteric artery
38
what is chronic mesenteric ischaemia, its presentation and management
AKA intestinal angina- is the result of narrowing of mesenteric blood vessles by atherosclerosis. Results in intermittent abdo pain when the blood supply cannot keep up with demand. central colicky abdo pain after eating (30 mins post, 1-2hr duration), weight loss (due to food avoidance), abdominal bruits. CT Angiography Reduce risk factors- smoking, diet Secondary prevention- statin, antiplatelet Revascularisation to improve blood flow- endovascular procedure (percutaneous mesenteric artery stenting) or open surgery
39
what is acute mesenteric ischaemia, its presentation and management
Typically cause by rapid blockage in blood flow through the superior mesenteric artery. This is caused usually by a throbus in the arty blocking blood flow. AF is a risk factor as the thrombus from the LA mobiliszes down the aorta to the superior mesenteric artery where it becomes stuck and cuts of the blood supply. Over time ischaemia to the bowel will result in nectosis of bowel tissue and perforation. non-specific abdo pain- can go into shock, peritonitis and sepsis Contrast CT, bloods- raised lactate & metabolic acidosis Remove or bypass thrombus- endovascular or open surgery
40
what assessed ulcerative colitis severity and what markers are needed
Truelove and witts severity score - #bowel movements per day - blood in stool - temperature - pulse >90 - anaemia - ESR
41
70% of patients with Primary sclerosing cholangitis have which other condition?
Ulcerative colitis
42
what is ulcerative colitis
the colon and rectum. NEVER goes to anus or past caecum. Caused by environmental triggers in genetically susceptible people. Most common form of IBD (UC or Crohn’s). It is relapsing-remitting. A severe exacerbation may be life threatening- worry about toxic megacolon.
43
presentation of ulcerative colitis
Diarrhoea- often bloody PR bleed Increased faecal frequency and urgency Tenesmus Abdominal Pain- left lower quadrant Weight loss Pallor, clubbing Abdominal distention, tenderness or mass Extra-intestinal manifestations Aphthous ulcers, erythema nodosum, VTE, metabolic bone disease, episcleritis
44
Investigations for ulcerative colitis
Truelove & witt severity Bloods- FBC, CRP/ESR, TFT, kidney & LFT, U&E, ferritin, vit d, b12, TTGT, TPMT Faecal calprotectin (<59 is normal) Stool saple MC&S Endoscopy- OGD and colonoscopy (pseudopolyp) w possibly biopsy. Abdo XR- mural thickening CT if toxic megacolon concern
45
Management of ulcerative colitis?
Mild-mod – 1st line mesalazine, 2nd line corticosteroids Severe – IV hydrocortisone, 2nd line –surgery- colectomy Conservative- assess disease impact, annual bloods, assess osteoporosis risk, raise awareness for colorectal cancer surveillance Remission- mesalazine, thiopurine
46
complications of ulcerative colitis
Psychological impact Toxic megacolon Bowel obstruction Bowel perforation Intestinal stricture Fistula Anaemia Malnutrition Colorectal cancer- surveillance screening pouchitis
47
what is crohn's
A form of IBD that can affect anywhere from the mouth to the anus in a discontinuous pattern (skip lesions). Inflammation is transmural, producing deep ulcers and fissures (cobblestone). It is not continuous, forming skip lesions. Relapsing-remitting.
48
signs of crohn's
Abdominal pain (colicky) Diarrhoea Fever RIF pain Weight loss Clubbing Apthous mouth ulcer Strictures Fistula Anaemia Erythema nodosum,anterior uveitis
49
Investigation & management of crohn's
Bloods (FBC (low HB., high platelet, high WCC) , U&E, LFT (low alb), high ESR, CRP Stool MC&S (exclude infective colitis) Faecal calprotectin AXR- Endoscopy (colonoscopy) and biopsy for definitive diagnosis – cobblestone appearance Stress, stop nsaids Induce remission Steroid for acute exacerbations – oral prednisolone 40mg x7 days (then reduce) Severe Flare- iv hydrocortisone 5-asa analogue- decrease the frequency of relapse in mild to moderate disease Immunosupressants- azathioprine, methotrexate Anti-TNFa agents – infliximab, adalimubab
50
management of stable angina
Modify risk factors- stop smoking , exercise, weight loss, HTN control, statins. Immediate symptomatic relief GTN – glyceril trinitrate causes vasolidation and helps to relieve symptoms. GTN can be repeated after 5 minutes. Beta blocker- bisoprolol 5,g OD or CCB (amlodipine 5mg) Aspirin 75mg OD Atorvastain 80mg PCI with coronary angioplast is offered to patients with proximal or extensive disease on CT coronary angiography. This involves putting a catheter into patients brachial or femoral artery, feeding up to coronary artery under xray and injecting contrast. Treated with balloon dilation and stent. CABG with severe stenosis
51
what is stable angina
A narrowing of the coronary arteries reduces blood flow to the myocardium. During exercise there is higher demand and therefore insufficient supply of blood to meet it. This causes angina. It is stable when relieved by rest of GTN.
52
stress incontinence presentation and management
The loss of control of urination. Can be stress or urge predominant Stress- weakens of the pelvic floor and sphincter muscles. Allows urine to leak at times of increased pressure on the bladder leakage When laughing, coughing or surprised Investigations Hx- caffeine, ETOH, med, BMI (ask frequency, nighttime urination and use of pads/clothes change Bimanual Examine- prolapse, vaginitis, masses, urethral diverticulum Bladder diary Urine dipstick Post-void residual bladder volume Management Avoid caffeine, diuretic, excessive fluid, kg loss 1st line – pelvic floor exercise (8 contractions TD for 3 months) 2nd- surgical- retropubic- mid urethral tape (TVT tension-free vaginal tape) 3rd- dulpxetine (if not surgical candidate)
53
urge incontinence presentation and management
The loss of control of urination. Can be stress or urge predominant Urge- is caused by overactivity of the detrusor muscle of the bladder. Sudden urge to pass urine Not reaching bathroom in time Conscious about having access to a toilet and may avoid places without access (QoL) Investigations Hx- caffeine, ETOH, med, BMI (ask frequency, nighttime urination and use of pads/clothes change Bimanual Examine- prolapse, vaginitis, masses, urethral diverticulum Bladder diary Urine dipstick Post-void residual bladder volume Management Bladder retraining 6w Bladder stabilizing drugs; 1- antimuscarinic (Oxybutynin, tolterodine, darifenacin)
54
FBO in eye management
high velocity then refer for slit lamp assessment- risk of penetration If low velocity/ no risky hx then attempt removal if confident Else refer use topical anaesthetic and the tip of a sterile needle at an oblique angle DONT USE COTTON BUD Topical prophylactic antibiotic (chloramphenicol) Oral analgesia
55
pericarditis diagnosis and management
Inflammation of the pericardium. Can be idiopathic or secondary to viruses, bacteria, fungi, MI, drugs or other reasons. Central chest pain Worse on inspiration or lying flat SOB Possible pericardial rub: due to friction between the pericardial layers, typically loudest at the left lower sternal border, best heard with the patient leaning forward ECG- tachycardia, saddle ST bloods NSAID’s (with PPI)- paracetamol Antibiotics- if caused by bacterial infection. Pericardial window surgery if symptoms persist.
56
what is polyarteritis nodosa
A rare disorder characterized by widespread inflammation, weakening and damage to small and medium-sized arteries. It can affect vessels in any organ or system including kidneys, heart, intestines, muscles. This can result in hypertension, aneurysms, thrombus or necrosis. Cause unknown but an attack can be triggered by drugs, vaccines or reaction to infection e.g. strep, stap, hep b.
57
breast abscess & management
A collection of pus within the breast lined with granulation tissue, most commonly developing from acute mastitis. Hx of recent mastitis or prior breast abscess Fever &/or general malaise A painful, swollen lump in the breast with redness and erythema Management Urgent referral to secondary care for confirmation of the diagnosis and management Drainage of the abscess (USS guided needle aspiration or surgical drainage) Culture of fluid from the abscess (which will guide the choice of antibiotic) Women can still breastfeed. If painful or infant refuses they can express milk by hand or pump until able to resume as normal.
58
management of OA
Conservative exercise, weight loss if relevant, heat or cold packs, joint supports, physio or occupational therapists Medical Analgesia- paracetamol, topical NSAIDs/capsaicin (if ineffective codine or oral NSAID + PPI (omepreazole). Steroid injections Surgical Joint replacement/fusion if severe.