Evolution, Viruses, and Prokaryotes Flashcards

(54 cards)

1
Q

Prion

A

Misfolded protein which causes a chain reaction leading to more misfolding. Examples: Mad cow, Kuru, Creutzfeldt-Jakob, Chronic Wasting Disease, Scrapie, Feline Spongiform Encephalopathy, Zoo animal encephalopathy, etc

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2
Q

Nucleoid

A

Complex of RNA, DNA and proteins in prokaryotes that forms a structure visible under light microscope

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3
Q

Virulent Virus

A

Virus capable of causing disease

Virus in lytic cycle

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4
Q



viral envelope

A

A membrane that encloses the capsids of some viruses. Normally includes specialized proteins that attach to host-cell surfaces.

Enveloped viruses form envelopes from the host cell which protect against detection by the immune system.

Host cell may not die from lysis, but will die from degrading cellular membrane

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5
Q

Kingdoms in Eukarya

A

Protista, Fungi, Animalae, Plantae

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6
Q

Phylogeny refers to

A

evolutionary relationships that are based on shared characteristics including physical traits, genetics, and behavior

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7
Q

Speciation

A

Members from a single species have evolved into different groups that can no longer produce fertile offspring

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8
Q

Gene pool

A

Total of all alleles in a population

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9
Q

Bacteriophage

A

a virus that infects and replicates within bacteria
Bacteriophage are composed of proteins that encapsulate a DNA or RNA genome, and may have relatively simple or elaborate structures.

many of the most complex capsids

Injects nuclei acids into host cell through tail

Viral enzymes digest hole in cell wall

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10
Q

Host cell in viral infection

A

Cell that is being infected

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11
Q

Lysogenic infection:

In a lysogenic infection, the viral DNA is incorporated into the host genome, or, if the virus is an RNA virus and it possesses the enzyme reverse transcriptase, DNA is actually reverse-transcribed from RNA and then incorporated into the host cell genome. When the host cell replicates its DNA, the viral DNA is replicated as well. A virus in a lysogenic cycle is called a temperate virus.

A

A host cell infected with a temperate virus may show no symptoms of infection. While the viral DNA remains incorporated in the host DNA, the virus is said to be dormant or latent, and is called a provirus (a prohage if the host cell is in a bacterium). the dormant virus may become active when the host cell is under some type of stress. ultaviolent light or carcinogens also may activate virus. When the virus becomes active, it becomes virulent.

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12
Q

Provirus or Prophage

A

Virus incorporated into host DNA

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13
Q

RNA-dependent RNA polymerase (RdRP)

A

Enzyme that can synthesize new RNA from template RNA. Makes either RNA+ from RNA- or vice versa

RNA+ encodes for proteins
RNA- complimentary strand that cannot encode for protein

Viruses preferentially carry either RNA+ or RNA-

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14
Q

Ontogeny recapitulates phylogeny?

A

Embryonic development retraces the steps of evolutionary history

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15
Q

Latent period with viral infection

A

Period from infection to lysis

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16
Q

Retrovirus

A

ssRNA virus that transcribe RNA into dsDNA by using reverse transcriptase (carried by retrovirus)

Example: HIV

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17
Q

Virus

A

Tiny infectious agents that usually lack cellular machinery to reproduce and leverage the transfer of genetic information to cells to reproduce. Not considered living. Can contain DNA or RNA

Known as viral particle or virion as mature virus outside of host

Can be thought of as a eukaryotic nucleus

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18
Q

Natural selection

A

Genes that are advantageous in environment are preferentially passed down from generation to generation

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19
Q

Random Mating

A

Organisms are equally likely to mate with each other regardless of their phenotype

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20
Q

Taxonomical Classification System

A

Domain, Kingdom, Phylum, Class, Order, Family, Genus, Species

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21
Q

Prokaryotes

A

single-celled organism that lacks a membrane-bound nucleus (karyon),mitochondria, or any other membrane-bound organelle.

Two domains- Archaea and Bacteria

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22
Q

Differential Reproduction

A

Animals within a species having different amount of reproduction to allow success of the organism to live on

23
Q

Mutational Equilibrium

A

Rate of forward mutations exactly equals rate of backward mutations.
Rare in real populations.

Evolutionary time can be measured by gradual changes in the genome.

24
Q

Mammals belong to class __ and Phylum ___

A

Mammalia, Chordata

25
Reasons organisms cannot produce fertile offspring
Geographic isolation, temporal isolation, genetic incompatibility
26
 | How does a viral infection happen?
* Begins when a virus adsorbs to a specific chemical receptor (usually glycoprotein) site on the host's cell membrane .
27
hardy weinberg equilibrium equations
p^2+2pq+q^2=1 | p+q=1
28
Hardy Weinberg equilibrium
1. Mutational equilibrium 2. Large population 3. Random Mating 4. Immigration or Emmigration must not change gene pool 5. No selection for fittest organism Conditions under which no evolution occurs. Idealization and not exactly possible
29
Polymorphism
Gene that has multiple alleles, corresponding to distinct forms of a phenotype
30
 | Archaea
Domain consisting of unicellular prokaryotes that have cell walls lacking peptidoglycan (MAIN DIFFERENCE FROM BACTERIA); corresponding to the kingdom Archaebacteria
31
Bacteria shapes
Cocci (spherical) Bacilli (rod-shaped) Spirilla (spiral-shaped) Spirochete (spiral shaped, but longer usually than spirilla) Filamentous (long and thin string-like) Vibrio (Slightly bent rod)
32
Describe the process of viral infection
Virus attaches to cell receptor, and either gets endocytosed/exocytosed by cell or injects it’s genetic material through cel membrane/wall Viral DNA then translocates to the nucleus, to hijack cellular machinery for DNA replication and transcription
33
Persistent versus Latent Viral Infection
Latent viruses have alternating periods of replication and asymptomaticness. Herpes B is persistent, herpes simplex is latent
34
No selection for fittest organism
No members of population exploit environment more efficiently than others
35
Genetic Drift
random change in allele and genotype frequencies as a result of a sampling error - the chances of a genetic drift increases with decrease in population size - small population size and genetic drift are associated with bottleneck effect     -- the result of unselective elimination of most members of a population - many alleles can be lost by the random loss of individuals from the populations (when the population recovers, genetic variability is reduced)
36
Lack of immigration and emmigration
New alleles not introduced and old alleles not eliminated due to movement of individuals in population
37
Allele
An allele is an alternative form of a gene (one member of a pair) that is located at a specific position on a specific
38
Three domains of life
1) Bacteria (prokaryotic) 2) Archaea (prokaryotic) 3) Eucarya (eukaryotic) CARL WOESE (1928-) classified them Viruses do not fall under any of these classifications because they are not prokaryotic or eukaryotic
39
Viroid
naked circular, highly complementary, single stranded RNA that is infectious with NO PROTEIN COAT. Does not encode genes (USES plants RNA-dependent RNA polymerase to replicate
40
Phylogeny
- The study of how living and extinct species are related | - the study of evolutionary history of different groups of organisms
41
Lytic infection
Virus commandeers host cell’s synthetic machinery to replicate viral Proteins RNA -> Proteins Cell may lyse with viruses or viruses may be released one at a time
42
Specialization
Organism tailors to specific niche in environment through behavior or resources, usually refers to subset of species rather than whole species
43
Nonenvelopes Viruses
Viruses not surrounded by cell membranes. | Typically cause cells to lyse in the lytic stage
44
Parasitic relationships
Relationships which only benefit one organism | Pathogenic bacteria are parasitic
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Species
All organisms that can reproduce fertile offspring with one another
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Types of genetic material viruses can hold
Single stranded DNA (ssDNA): Translocates to nucleus and DNA polymerase replicates complimentary strand Double stranded RNA (dsRNA): Strands separate to form RNA- and RNA+
47
Genetic Material in Prokaryotes
Typically a single circular double-stranded molecule of DNA. Molecule is twisted into supercoils Archaea- have histones Bacteria- have proteins distinct from histones
48
Constituents of a Virus
Capsid- protein coat Genetic material- DNA or RNA No organelles or nuclei Usually an envelope- lipid rich
49
Non random mating
Any mating system in which males are not randomly assigned to females. -females choose out of visual appeal or those who live nearby, etc.
50
Symbiotic relationships
Relationship beneficial to two organisms E.g., bacteria in intestinal tract help humans digest food efficiently and benefit by receiving nutrients
51
Adaptation
Genetic or behavioral changes that are advantageous in given environment
52
How can we measure success of gene?
Percent increase in representation in gene pool of next generation
53
Bacteriophage
A virus that infects bacteria Injects nuclei acids into host cell through tail Viral enzymes digest hole in cell wall
54
Causes of speciation
Polymorphisms make speciation possible. Inbreeding (mating of relatives) increases num of homozygous individuals in population and w/ geographic separation can cause speciation. Random events can cause a bottleneck. Specialization and adaptation